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Items: 1 to 20 of 190

1.

Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells.

Chen C, Cano M, Wang JJ, Li J, Huang C, Yu Q, Herbert TP, Handa JT, Zhang SX.

Antioxid Redox Signal. 2014 May 10;20(14):2091-106. doi: 10.1089/ars.2013.5240. Epub 2013 Dec 17.

2.

Activation of the UPR protects against cigarette smoke-induced RPE apoptosis through up-regulation of Nrf2.

Huang C, Wang JJ, Ma JH, Jin C, Yu Q, Zhang SX.

J Biol Chem. 2015 Feb 27;290(9):5367-80. doi: 10.1074/jbc.M114.603738. Epub 2015 Jan 7.

3.

X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium.

Zhong Y, Li J, Wang JJ, Chen C, Tran JT, Saadi A, Yu Q, Le YZ, Mandal MN, Anderson RE, Zhang SX.

PLoS One. 2012;7(6):e38616. doi: 10.1371/journal.pone.0038616. Epub 2012 Jun 8.

4.

Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation.

Kunchithapautham K, Atkinson C, Rohrer B.

J Biol Chem. 2014 May 23;289(21):14534-46. doi: 10.1074/jbc.M114.564674. Epub 2014 Apr 7.

5.

Quinotrierixin inhibits proliferation of human retinal pigment epithelial cells.

Chen C, Wang JJ, Li J, Yu Q, Zhang SX.

Mol Vis. 2013;19:39-46. Epub 2013 Jan 7.

6.

Cigarette smoke-related hydroquinone dysregulates MCP-1, VEGF and PEDF expression in retinal pigment epithelium in vitro and in vivo.

Pons M, Marin-Castaño ME.

PLoS One. 2011 Feb 28;6(2):e16722. doi: 10.1371/journal.pone.0016722.

7.

The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.

Chan JY, Luzuriaga J, Maxwell EL, West PK, Bensellam M, Laybutt DR.

Mol Cell Endocrinol. 2015 Sep 15;413:189-201. doi: 10.1016/j.mce.2015.06.025. Epub 2015 Jun 30.

PMID:
26135354
8.

Expression of endoplasmic reticulum stress markers GRP78 and CHOP induced by oxidative stress in blue light-mediated damage of A2E-containing retinal pigment epithelium cells.

Feng J, Chen X, Sun X, Wang F, Sun X.

Ophthalmic Res. 2014;52(4):224-33. doi: 10.1159/000363387. Epub 2014 Nov 12.

PMID:
25402962
10.

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.

Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P.

Arch Toxicol. 2014 Jun;88(6):1267-80. doi: 10.1007/s00204-014-1240-8. Epub 2014 Apr 20.

PMID:
24748426
11.

Erp29 Attenuates Cigarette Smoke Extract-Induced Endoplasmic Reticulum Stress and Mitigates Tight Junction Damage in Retinal Pigment Epithelial Cells.

Huang C, Wang JJ, Jing G, Li J, Jin C, Yu Q, Falkowski MW, Zhang SX.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6196-207. doi: 10.1167/iovs.15-16795.

12.

Involvement of endoplasmic reticulum stress in all-trans-retinal-induced retinal pigment epithelium degeneration.

Li J, Cai X, Xia Q, Yao K, Chen J, Zhang Y, Naranmandura H, Liu X, Wu Y.

Toxicol Sci. 2015 Jan;143(1):196-208. doi: 10.1093/toxsci/kfu223. Epub 2014 Oct 20.

PMID:
25331497
13.

Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells.

Cano M, Wang L, Wan J, Barnett BP, Ebrahimi K, Qian J, Handa JT.

Free Radic Biol Med. 2014 Apr;69:1-14. doi: 10.1016/j.freeradbiomed.2014.01.004. Epub 2014 Jan 14.

14.

Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress.

Takayanagi S, Fukuda R, Takeuchi Y, Tsukada S, Yoshida K.

Cell Stress Chaperones. 2013 Jan;18(1):11-23. doi: 10.1007/s12192-012-0351-5. Epub 2012 Jul 18.

15.

Molecular regulation of cigarette smoke induced-oxidative stress in human retinal pigment epithelial cells: implications for age-related macular degeneration.

Bertram KM, Baglole CJ, Phipps RP, Libby RT.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1200-10. doi: 10.1152/ajpcell.00126.2009. Epub 2009 Sep 16.

16.

Role of ZnS Nanoparticles on Endoplasmic Reticulum Stress-mediated Apoptosis in Retinal Pigment Epithelial Cells.

Karthikeyan B, Arun A, Harini L, Sundar K, Kathiresan T.

Biol Trace Elem Res. 2016 Apr;170(2):390-400. doi: 10.1007/s12011-015-0493-2. Epub 2015 Sep 2.

PMID:
26329999
17.

Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage.

Lugea A, Tischler D, Nguyen J, Gong J, Gukovsky I, French SW, Gorelick FS, Pandol SJ.

Gastroenterology. 2011 Mar;140(3):987-97. doi: 10.1053/j.gastro.2010.11.038. Epub 2010 Nov 25.

18.

Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues.

Zhang H, Nakajima S, Kato H, Gu L, Yoshitomi T, Nagai K, Shinmori H, Kokubo S, Kitamura M.

Br J Pharmacol. 2013 Oct;170(4):822-34. doi: 10.1111/bph.12306.

19.

Hepatic Xbp1 Gene Deletion Promotes Endoplasmic Reticulum Stress-induced Liver Injury and Apoptosis.

Olivares S, Henkel AS.

J Biol Chem. 2015 Dec 11;290(50):30142-51. doi: 10.1074/jbc.M115.676239. Epub 2015 Oct 26.

20.

Inhibition of casein kinase 2 modulates XBP1-GRP78 arm of unfolded protein responses in cultured glial cells.

Hosoi T, Korematsu K, Horie N, Suezawa T, Okuma Y, Nomura Y, Ozawa K.

PLoS One. 2012;7(6):e40144. doi: 10.1371/journal.pone.0040144. Epub 2012 Jun 29.

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