Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 127

1.

Development of a bio-relevant dissolution test device simulating mechanical aspects present in the fed stomach.

Koziolek M, Görke K, Neumann M, Garbacz G, Weitschies W.

Eur J Pharm Sci. 2014 Jun 16;57:250-6. doi: 10.1016/j.ejps.2013.09.004. Epub 2013 Sep 16.

PMID:
24051217
2.

Simulating the postprandial stomach: physiological considerations for dissolution and release testing.

Koziolek M, Garbacz G, Neumann M, Weitschies W.

Mol Pharm. 2013 May 6;10(5):1610-22. doi: 10.1021/mp300604u. Epub 2013 Apr 1. Review.

PMID:
23506381
3.

Understanding the in vivo performance of enteric coated tablets using an in vitro-in silico-in vivo approach: case example diclofenac.

Kambayashi A, Blume H, Dressman J.

Eur J Pharm Biopharm. 2013 Nov;85(3 Pt B):1337-47. doi: 10.1016/j.ejpb.2013.09.009. Epub 2013 Sep 18.

PMID:
24056057
4.

Bio-relevant dissolution testing of hard capsules prepared from different shell materials using the dynamic open flow through test apparatus.

Garbacz G, Cadé D, Benameur H, Weitschies W.

Eur J Pharm Sci. 2014 Jun 16;57:264-72. doi: 10.1016/j.ejps.2013.08.039. Epub 2013 Sep 8.

PMID:
24021609
5.

Predicting the oral pharmacokinetic profiles of multiple-unit (pellet) dosage forms using a modeling and simulation approach coupled with biorelevant dissolution testing: case example diclofenac sodium.

Kambayashi A, Blume H, Dressman JB.

Eur J Pharm Biopharm. 2014 Jul;87(2):236-43. doi: 10.1016/j.ejpb.2014.01.007. Epub 2014 Jan 23.

PMID:
24462791
6.

Simulating the postprandial stomach: biorelevant test methods for the estimation of intragastric drug dissolution.

Koziolek M, Garbacz G, Neumann M, Weitschies W.

Mol Pharm. 2013 Jun 3;10(6):2211-21. doi: 10.1021/mp300607e. Epub 2013 May 8. Review.

PMID:
23654347
7.

Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses.

Garbacz G, Wedemeyer RS, Nagel S, Giessmann T, Mönnikes H, Wilson CG, Siegmund W, Weitschies W.

Eur J Pharm Biopharm. 2008 Oct;70(2):421-8. doi: 10.1016/j.ejpb.2008.05.029. Epub 2008 Jun 7.

PMID:
18582568
8.

Effect of surfactants, gastric emptying, and dosage form on supersaturation of dipyridamole in an in vitro model simulating the stomach and duodenum.

Mitra A, Fadda HM.

Mol Pharm. 2014 Aug 4;11(8):2835-44. doi: 10.1021/mp500196f. Epub 2014 Jul 15.

PMID:
25025699
9.

The delayed dissolution of paracetamol products in the canine fed stomach can be predicted in vitro but it does not affect the onset of plasma levels.

Kalantzi L, Polentarutti B, Albery T, Laitmer D, Abrahamsson B, Dressman J, Reppas C.

Int J Pharm. 2005 May 30;296(1-2):87-93. Epub 2005 Apr 7.

PMID:
15885459
10.

Impact of the intragastric location of extended release tablets on food interactions.

Weitschies W, Wedemeyer RS, Kosch O, Fach K, Nagel S, Söderlind E, Trahms L, Abrahamsson B, Mönnikes H.

J Control Release. 2005 Nov 28;108(2-3):375-85. Epub 2005 Oct 5.

PMID:
16213057
11.

A novel in vitro and numerical analysis of shear-induced drug release from extended-release tablets in the fed stomach.

Abrahamsson B, Pal A, Sjöberg M, Carlsson M, Laurell E, Brasseur JG.

Pharm Res. 2005 Aug;22(8):1215-26. Epub 2005 Aug 3.

PMID:
16078131
12.

The role of individual gastric emptying of pellets in the prediction of diclofenac in vivo dissolution.

Klein S, Garbacz G, Pišlar M, Locatelli I, Liu C, Weitschies W, Siegmund W, Mrhar A, Bogataj M.

J Control Release. 2013 Mar 28;166(3):286-93. doi: 10.1016/j.jconrel.2012.12.032. Epub 2013 Jan 8.

PMID:
23306025
13.

Application of the Dynamic Gastric Model to evaluate the effect of food on the drug release characteristics of a hydrophilic matrix formulation.

Chessa S, Huatan H, Levina M, Mehta RY, Ferrizzi D, Rajabi-Siahboomi AR.

Int J Pharm. 2014 May 15;466(1-2):359-67. doi: 10.1016/j.ijpharm.2014.03.031. Epub 2014 Mar 20.

PMID:
24657141
14.

Influence of the physiological variability of fasted gastric pH and tablet retention time on the variability of in vitro dissolution and simulated plasma profiles.

Kovačič NN, Pišlar M, Ilić I, Mrhar A, Bogataj M.

Int J Pharm. 2014 Oct 1;473(1-2):552-9. doi: 10.1016/j.ijpharm.2014.07.031. Epub 2014 Jul 24.

PMID:
25064726
15.

Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form.

Jantratid E, De Maio V, Ronda E, Mattavelli V, Vertzoni M, Dressman JB.

Eur J Pharm Sci. 2009 Jun 28;37(3-4):434-41. doi: 10.1016/j.ejps.2009.03.015. Epub 2009 Apr 5.

PMID:
19491035
16.

The effect of food on the pharmacokinetics of nifedipine in two slow release formulations: pronounced lag-time after a high fat breakfast.

Schug BS, Brendel E, Chantraine E, Wolf D, Martin W, Schall R, Blume HH.

Br J Clin Pharmacol. 2002 Jun;53(6):582-8.

17.

Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity.

Radwan A, Amidon GL, Langguth P.

Biopharm Drug Dispos. 2012 Oct;33(7):403-16. doi: 10.1002/bdd.1798. Epub 2012 Aug 11.

19.
20.

A biorelevant dissolution stress test device - background and experiences.

Garbacz G, Klein S, Weitschies W.

Expert Opin Drug Deliv. 2010 Nov;7(11):1251-61. doi: 10.1517/17425247.2010.527943. Review.

PMID:
20977290

Supplemental Content

Support Center