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Items: 1 to 20 of 114

1.

Proline substitution of dimer interface β-strand residues as a strategy for the design of functional monomeric proteins.

Joseph PR, Poluri KM, Gangavarapu P, Rajagopalan L, Raghuwanshi S, Richardson RM, Garofalo RP, Rajarathnam K.

Biophys J. 2013 Sep 17;105(6):1491-501. doi: 10.1016/j.bpj.2013.08.008.

2.

Structural basis for differential binding of the interleukin-8 monomer and dimer to the CXCR1 N-domain: role of coupled interactions and dynamics.

Ravindran A, Joseph PR, Rajarathnam K.

Biochemistry. 2009 Sep 22;48(37):8795-805. doi: 10.1021/bi901194p.

3.

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions.

Joseph PR, Mosier PD, Desai UR, Rajarathnam K.

Biochem J. 2015 Nov 15;472(1):121-33. doi: 10.1042/BJ20150059. Epub 2015 Sep 14.

4.

Role of intramolecular disulfides in stability and structure of a noncovalent homodimer.

Rajagopalan L, Chin CC, Rajarathnam K.

Biophys J. 2007 Sep 15;93(6):2129-34. Epub 2007 May 18.

5.

Role of the amino acid sequence in domain swapping of the B1 domain of protein G.

Sirota FL, Héry-Huynh S, Maurer-Stroh S, Wodak SJ.

Proteins. 2008 Jul;72(1):88-104. doi: 10.1002/prot.21901.

PMID:
18186476
6.
7.

Control activity of yeast geranylgeranyl diphosphate synthase from dimer interface through H-bonds and hydrophobic interaction.

Chang CK, Teng KH, Lin SW, Chang TH, Liang PH.

Biochemistry. 2013 Apr 23;52(16):2783-92. doi: 10.1021/bi4001276. Epub 2013 Apr 11.

PMID:
23534508
8.

Probing receptor binding activity of interleukin-8 dimer using a disulfide trap.

Rajarathnam K, Prado GN, Fernando H, Clark-Lewis I, Navarro J.

Biochemistry. 2006 Jun 27;45(25):7882-8.

9.

Dynamics simulation of soybean agglutinin (SBA) dimer reveals the impact of glycosylation on its enhanced structural stability.

Halder S, Surolia A, Mukhopadhyay C.

Carbohydr Res. 2016 Jun 16;428:8-17. doi: 10.1016/j.carres.2016.04.009. Epub 2016 Apr 12.

PMID:
27108103
10.

Biochemical, mutational and in silico structural evidence for a functional dimeric form of the ornithine decarboxylase from Entamoeba histolytica.

Preeti, Tapas S, Kumar P, Madhubala R, Tomar S.

PLoS Negl Trop Dis. 2012;6(2):e1559. doi: 10.1371/journal.pntd.0001559. Epub 2012 Feb 28.

11.

Sequence conservation provides the best prediction of the role of proline residues in p13suc1.

Schymkowitz JW, Rousseau F, Itzhaki LS.

J Mol Biol. 2000 Aug 4;301(1):199-204.

PMID:
10926502
12.

The solution structure of melanoma growth stimulating activity.

Fairbrother WJ, Reilly D, Colby TJ, Hesselgesser J, Horuk R.

J Mol Biol. 1994 Sep 23;242(3):252-70.

PMID:
8089846
13.

Dynamics and thermodynamic properties of CXCL7 chemokine.

Herring CA, Singer CM, Ermakova EA, Khairutdinov BI, Zuev YF, Jacobs DJ, Nesmelova IV.

Proteins. 2015 Nov;83(11):1987-2007. doi: 10.1002/prot.24913. Epub 2015 Sep 2.

PMID:
26297927
14.

Manipulating monomer-dimer equilibrium of bovine Beta -lactoglobulin by amino acid substitution.

Sakurai K, Goto Y.

J Biol Chem. 2002 Jul 12;277(28):25735-40. Epub 2002 May 2.

15.

Three-dimensional domain swapping in p13suc1 occurs in the unfolded state and is controlled by conserved proline residues.

Rousseau F, Schymkowitz JW, Wilkinson HR, Itzhaki LS.

Proc Natl Acad Sci U S A. 2001 May 8;98(10):5596-601.

16.

Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase.

Reboul CF, Porebski BT, Griffin MD, Dobson RC, Perugini MA, Gerrard JA, Buckle AM.

PLoS Comput Biol. 2012;8(6):e1002537. doi: 10.1371/journal.pcbi.1002537. Epub 2012 Jun 7.

17.

The structure of a monomeric mutant Cks protein reveals multiple functions for a conserved hinge-region proline.

Balog ER, Saetern OC, Finch W, Hoeft CO, Thai V, Harvey SL, Kellogg DR, Rubin SM.

J Mol Biol. 2011 Aug 19;411(3):520-8. doi: 10.1016/j.jmb.2011.05.045. Epub 2011 Jun 17.

PMID:
21704044
19.
20.

Non-equivalent role of inter- and intramolecular hydrogen bonds in the insulin dimer interface.

Antolíková E, Žáková L, Turkenburg JP, Watson CJ, Hančlová I, Šanda M, Cooper A, Kraus T, Brzozowski AM, Jiráček J.

J Biol Chem. 2011 Oct 21;286(42):36968-77. doi: 10.1074/jbc.M111.265249. Epub 2011 Aug 31.

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