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Items: 1 to 20 of 103

1.

Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.

Kleber ME, Seppälä I, Pilz S, Hoffmann MM, Tomaschitz A, Oksala N, Raitoharju E, Lyytikäinen LP, Mäkelä KM, Laaksonen R, Kähönen M, Raitakari OT, Huang J, Kienreich K, Fahrleitner-Pammer A, Drechsler C, Krane V, Boehm BO, Koenig W, Wanner C, Lehtimäki T, März W, Meinitzer A.

Circ Cardiovasc Genet. 2013 Oct;6(5):505-13. doi: 10.1161/CIRCGENETICS.113.000108. Epub 2013 Sep 18.

2.

Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies.

Choe CU, Atzler D, Wild PS, Carter AM, Böger RH, Ojeda F, Simova O, Stockebrand M, Lackner K, Nabuurs C, Marescau B, Streichert T, Müller C, Lüneburg N, De Deyn PP, Benndorf RA, Baldus S, Gerloff C, Blankenberg S, Heerschap A, Grant PJ, Magnus T, Zeller T, Isbrandt D, Schwedhelm E.

Circulation. 2013 Sep 24;128(13):1451-61. doi: 10.1161/CIRCULATIONAHA.112.000580. Epub 2013 Sep 4.

3.

Homoarginine, cardiovascular risk, and mortality.

März W, Meinitzer A, Drechsler C, Pilz S, Krane V, Kleber ME, Fischer J, Winkelmann BR, Böhm BO, Ritz E, Wanner C.

Circulation. 2010 Sep 7;122(10):967-75. doi: 10.1161/CIRCULATIONAHA.109.908988. Epub 2010 Aug 23.

4.

[Genetic factors in myocardial infarction--Results from a candidate gene and a genome-wide approach between beta blockers].

Hengstenberg C, Bröckel U, Holmer S, Mayer B, Fischer M, Baessler A, Erdmann J, Lieb W, Löwel H, Riegger G, Schunkert H.

Herz. 2002 Nov;27(7):649-61. German. Erratum in: Herz. 2003 May;28(3):266.

PMID:
12439636
5.

A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.

Julià A, Domènech E, Ricart E, Tortosa R, García-Sánchez V, Gisbert JP, Nos Mateu P, Gutiérrez A, Gomollón F, Mendoza JL, Garcia-Planella E, Barreiro-de Acosta M, Muñoz F, Vera M, Saro C, Esteve M, Andreu M, Alonso A, López-Lasanta M, Codó L, Gelpí JL, García-Montero AC, Bertranpetit J, Absher D, Panés J, Marsal S.

Gut. 2013 Oct;62(10):1440-5. doi: 10.1136/gutjnl-2012-302865. Epub 2012 Aug 30.

PMID:
22936669
6.

Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study.

Athanasiu L, Brown AA, Birkenaes AB, Mattingsdal M, Agartz I, Melle I, Steen VM, Andreassen OA, Djurovic S.

Psychiatry Res. 2012 May 30;197(3):327-36. doi: 10.1016/j.psychres.2011.12.036. Epub 2012 Mar 13.

PMID:
22417934
7.

Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.

Lin X, Lu D, Gao Y, Tao S, Yang X, Feng J, Tan A, Zhang H, Hu Y, Qin X, Kim ST, Peng T, Li L, Mo L, Zhang S, Trent JM, Mo Z, Zheng SL, Xu J, Sun J.

Hum Mol Genet. 2012 Jun 1;21(11):2610-7. doi: 10.1093/hmg/dds062. Epub 2012 Feb 24.

PMID:
22367966
8.

Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.

Mäkelä KM, Seppälä I, Hernesniemi JA, Lyytikäinen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kähönen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjärvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JS, Kähönen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, März W, Lehtimäki T.

Circ Cardiovasc Genet. 2013 Feb;6(1):73-81. doi: 10.1161/CIRCGENETICS.112.964965. Epub 2012 Dec 17.

9.

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

Hazra A, Kraft P, Lazarus R, Chen C, Chanock SJ, Jacques P, Selhub J, Hunter DJ.

Hum Mol Genet. 2009 Dec 1;18(23):4677-87. doi: 10.1093/hmg/ddp428. Epub 2009 Sep 10.

10.

A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study.

Panicker V, Wilson SG, Walsh JP, Richards JB, Brown SJ, Beilby JP, Bremner AP, Surdulescu GL, Qweitin E, Gillham-Nasenya I, Soranzo N, Lim EM, Fletcher SJ, Spector TD.

Am J Hum Genet. 2010 Sep 10;87(3):430-5. doi: 10.1016/j.ajhg.2010.08.005.

11.

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.

Erdmann J, Willenborg C, Nahrstaedt J, Preuss M, König IR, Baumert J, Linsel-Nitschke P, Gieger C, Tennstedt S, Belcredi P, Aherrahrou Z, Klopp N, Loley C, Stark K, Hengstenberg C, Bruse P, Freyer J, Wagner AK, Medack A, Lieb W, Grosshennig A, Sager HB, Reinhardt A, Schäfer A, Schreiber S, El Mokhtari NE, Raaz-Schrauder D, Illig T, Garlichs CD, Ekici AB, Reis A, Schrezenmeir J, Rubin D, Ziegler A, Wichmann HE, Doering A, Meisinger C, Meitinger T, Peters A, Schunkert H.

Eur Heart J. 2011 Jan;32(2):158-68. doi: 10.1093/eurheartj/ehq405. Epub 2010 Nov 18.

PMID:
21088011
12.

A variant in the ABO gene explains the variation in soluble E-selectin levels-results from dense genotyping in two independent populations.

Karakas M, Baumert J, Kleber ME, Thorand B, Dallmeier D, Silbernagel G, Grammer TB, Rottbauer W, Meisinger C, Illig T, März W, Koenig W.

PLoS One. 2012;7(12):e51441. doi: 10.1371/journal.pone.0051441. Epub 2012 Dec 28.

13.

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.

Ikram MK, Sim X, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, Wang JJ, Klein R, Klein BE, Breteler MM, Cheung N, Liew G, Mitchell P, Uitterlinden AG, Rivadeneira F, Hofman A, de Jong PT, van Duijn CM, Kao L, Cheng CY, Smith AV, Glazer NL, Lumley T, McKnight B, Psaty BM, Jonasson F, Eiriksdottir G, Aspelund T; Global BPgen Consortium, Harris TB, Launer LJ, Taylor KD, Li X, Iyengar SK, Xi Q, Sivakumaran TA, Mackey DA, Macgregor S, Martin NG, Young TL, Bis JC, Wiggins KL, Heckbert SR, Hammond CJ, Andrew T, Fahy S, Attia J, Holliday EG, Scott RJ, Islam FM, Rotter JI, McAuley AK, Boerwinkle E, Tai ES, Gudnason V, Siscovick DS, Vingerling JR, Wong TY.

PLoS Genet. 2010 Oct 28;6(10):e1001184. doi: 10.1371/journal.pgen.1001184. Erratum in: PLoS Genet. 2010;6(11). doi: 10.1371/annotation/841bfadf-85d1-4059-894f-2863d73fa963. Xueling, Sim [corrected to Sim, Xueling].

14.

Low homoarginine concentration is a novel risk factor for heart disease.

Pilz S, Meinitzer A, Tomaschitz A, Drechsler C, Ritz E, Krane V, Wanner C, Boehm BO, März W.

Heart. 2011 Aug;97(15):1222-7. doi: 10.1136/hrt.2010.220731. Epub 2011 May 10.

PMID:
21558479
15.

Genome-wide association study of serum albumin:globulin ratio in Korean populations.

Hong KW, Jin HS, Song D, Kwak HK, Kim SS, Kim Y.

J Hum Genet. 2013 Mar;58(3):174-7. doi: 10.1038/jhg.2012.130. Epub 2013 Jan 10.

PMID:
23303382
16.

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

Seppälä I, Kleber ME, Lyytikäinen LP, Hernesniemi JA, Mäkelä KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kähönen N, Alfthan G, Viikari JS, Kähonen M, Raitakari OT, März W, Meinitzer A, Lehtimäki T; AtheroRemo Consortium.

Eur Heart J. 2014 Feb;35(8):524-31. doi: 10.1093/eurheartj/eht447. Epub 2013 Oct 24.

17.

Promiscuous activity of arginine:glycine amidinotransferase is responsible for the synthesis of the novel cardiovascular risk factor homoarginine.

Davids M, Ndika JD, Salomons GS, Blom HJ, Teerlink T.

FEBS Lett. 2012 Oct 19;586(20):3653-7. doi: 10.1016/j.febslet.2012.08.020. Epub 2012 Aug 29.

18.

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.

Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, Morizono T, Hosono N, Kawaguchi T, Takazoe M, Yamada T, Suzuki Y, Tanaka H, Motoya S, Hosokawa M, Arimura Y, Shinomura Y, Matsui T, Matsumoto T, Iida M, Tsunoda T, Nakamura Y, Kamatani N, Kubo M.

Gastroenterology. 2013 Apr;144(4):781-8. doi: 10.1053/j.gastro.2012.12.021. Epub 2012 Dec 22.

PMID:
23266558
19.

Opposite associations of plasma homoarginine and ornithine with arginine in healthy children and adolescents.

Jaźwińska-Kozuba A, Martens-Lobenhoffer J, Kruszelnicka O, Rycaj J, Chyrchel B, Surdacki A, Bode-Böger SM.

Int J Mol Sci. 2013 Nov 4;14(11):21819-32. doi: 10.3390/ijms141121819.

20.

A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2.

Rodionov RN, Oppici E, Martens-Lobenhoffer J, Jarzebska N, Brilloff S, Burdin D, Demyanov A, Kolouschek A, Leiper J, Maas R, Cellini B, Weiss N, Bode-Böger SM.

Sci Rep. 2016 Oct 18;6:35277. doi: 10.1038/srep35277.

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