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Items: 1 to 20 of 210

1.

Nur77 suppresses pulmonary artery smooth muscle cell proliferation through inhibition of the STAT3/Pim-1/NFAT pathway.

Liu Y, Zhang J, Yi B, Chen M, Qi J, Yin Y, Lu X, Jasmin JF, Sun J.

Am J Respir Cell Mol Biol. 2014 Feb;50(2):379-88. doi: 10.1165/rcmb.2013-0198OC.

2.

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension.

Paulin R, Meloche J, Jacob MH, Bisserier M, Courboulin A, Bonnet S.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1798-809. doi: 10.1152/ajpheart.00654.2011.

3.

MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells.

Kang K, Peng X, Zhang X, Wang Y, Zhang L, Gao L, Weng T, Zhang H, Ramchandran R, Raj JU, Gou D, Liu L.

J Biol Chem. 2013 Aug 30;288(35):25414-27. doi: 10.1074/jbc.M113.460287.

4.

Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.

Meloche J, Courchesne A, Barrier M, Carter S, Bisserier M, Paulin R, Lauzon-Joset JF, Breuils-Bonnet S, Tremblay É, Biardel S, Racine C, Courture C, Bonnet P, Majka SM, Deshaies Y, Picard F, Provencher S, Bonnet S.

J Am Heart Assoc. 2013 Jan 16;2(1):e005157. doi: 10.1161/JAHA.112.005157.

5.

Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells.

Wang C, Li JF, Zhao L, Liu J, Wan J, Wang YX, Wang J, Wang C.

Respir Res. 2009 Dec 11;10:123. doi: 10.1186/1465-9921-10-123.

6.

Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension.

Yamanaka R, Otsuka F, Nakamura K, Yamashita M, Otani H, Takeda M, Matsumoto Y, Kusano KF, Ito H, Makino H.

Hypertens Res. 2010 May;33(5):435-45. doi: 10.1038/hr.2010.16.

PMID:
20186146
7.

miRNA-34a promotes proliferation of human pulmonary artery smooth muscle cells by targeting PDGFRA.

Wang P, Xu J, Hou Z, Wang F, Song Y, Wang J, Zhu H, Jin H.

Cell Prolif. 2016 Aug;49(4):484-93. doi: 10.1111/cpr.12265.

PMID:
27302634
8.

Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.

Kishimoto Y, Kato T, Ito M, Azuma Y, Fukasawa Y, Ohno K, Kojima S.

J Thorac Cardiovasc Surg. 2015 Sep;150(3):645-54.e3. doi: 10.1016/j.jtcvs.2015.05.052.

PMID:
26095621
9.

Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension.

Paulin R, Courboulin A, Meloche J, Mainguy V, Dumas de la Roque E, Saksouk N, Côté J, Provencher S, Sussman MA, Bonnet S.

Circulation. 2011 Mar 22;123(11):1205-15. doi: 10.1161/CIRCULATIONAHA.110.963314.

10.

Nur77 downregulation triggers pulmonary artery smooth muscle cell proliferation and migration in mice with hypoxic pulmonary hypertension via the Axin2-β-catenin signaling pathway.

Nie X, Tan J, Dai Y, Mao W, Chen Y, Qin G, Li G, Shen C, Zhao J, Chen J.

Vascul Pharmacol. 2016 Dec;87:230-241. doi: 10.1016/j.vph.2016.11.002.

PMID:
27871853
11.

Role of Src tyrosine kinases in experimental pulmonary hypertension.

Pullamsetti SS, Berghausen EM, Dabral S, Tretyn A, Butrous E, Savai R, Butrous G, Dahal BK, Brandes RP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Rosenkranz S, Schermuly RT.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1354-65. doi: 10.1161/ATVBAHA.112.248500.

12.

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

Biasin V, Chwalek K, Wilhelm J, Best J, Marsh LM, Ghanim B, Klepetko W, Fink L, Schermuly RT, Weissmann N, Olschewski A, Kwapiszewska G.

Int J Biochem Cell Biol. 2014 Sep;54:137-48. doi: 10.1016/j.biocel.2014.06.020.

PMID:
25016214
13.

Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension.

Courboulin A, Tremblay VL, Barrier M, Meloche J, Jacob MH, Chapolard M, Bisserier M, Paulin R, Lambert C, Provencher S, Bonnet S.

Respir Res. 2011 Sep 27;12:128. doi: 10.1186/1465-9921-12-128.

14.

PAR-2 inhibition reverses experimental pulmonary hypertension.

Kwapiszewska G, Markart P, Dahal BK, Kojonazarov B, Marsh LM, Schermuly RT, Taube C, Meinhardt A, Ghofrani HA, Steinhoff M, Seeger W, Preissner KT, Olschewski A, Weissmann N, Wygrecka M.

Circ Res. 2012 Apr 27;110(9):1179-91. doi: 10.1161/CIRCRESAHA.111.257568.

15.

STARS knockout attenuates hypoxia-induced pulmonary arterial hypertension by suppressing pulmonary arterial smooth muscle cell proliferation.

Shi Z, Wu H, Luo J, Sun X.

Biomed Pharmacother. 2017 Mar;87:397-404. doi: 10.1016/j.biopha.2016.12.126.

PMID:
28068629
16.

Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension.

Yang J, Li X, Al-Lamki RS, Wu C, Weiss A, Berk J, Schermuly RT, Morrell NW.

Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):34-42. doi: 10.1161/ATVBAHA.112.300121.

17.

Inhibition of CXCL12/CXCR4 suppresses pulmonary arterial smooth muscle cell proliferation and cell cycle progression via PI3K/Akt pathway under hypoxia.

Wei L, Zhang B, Cao W, Xing H, Yu X, Zhu D.

J Recept Signal Transduct Res. 2015;35(4):329-39. doi: 10.3109/10799893.2014.984308.

PMID:
25421526
18.

Role for DNA damage signaling in pulmonary arterial hypertension.

Meloche J, Pflieger A, Vaillancourt M, Paulin R, Potus F, Zervopoulos S, Graydon C, Courboulin A, Breuils-Bonnet S, Tremblay E, Couture C, Michelakis ED, Provencher S, Bonnet S.

Circulation. 2014 Feb 18;129(7):786-97. doi: 10.1161/CIRCULATIONAHA.113.006167.

19.

Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH.

Courboulin A, Barrier M, Perreault T, Bonnet P, Tremblay VL, Paulin R, Tremblay E, Lambert C, Jacob MH, Bonnet SN, Provencher S, Bonnet S.

Eur Respir J. 2012 Sep;40(3):618-29. doi: 10.1183/09031936.00084211.

20.

Involvement of Gax gene in hypoxia-induced pulmonary hypertension, proliferation, and apoptosis of arterial smooth muscle cells.

Xia S, Tai X, Wang Y, An X, Qian G, Dong J, Wang X, Sha B, Wang D, Murthi P, Kalionis B, Wang X, Bai C.

Am J Respir Cell Mol Biol. 2011 Jan;44(1):66-73. doi: 10.1165/rcmb.2008-0442OC.

PMID:
20160044
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