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Items: 1 to 20 of 112

1.

Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation.

Chanda S, Marro S, Wernig M, Südhof TC.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16622-7. doi: 10.1073/pnas.1316240110. Epub 2013 Sep 17.

2.

An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.

Etherton MR, Tabuchi K, Sharma M, Ko J, Südhof TC.

EMBO J. 2011 Jun 3;30(14):2908-19. doi: 10.1038/emboj.2011.182.

3.

Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking.

Chanda S, Aoto J, Lee SJ, Wernig M, Südhof TC.

Mol Psychiatry. 2016 Feb;21(2):169-77. doi: 10.1038/mp.2015.20. Epub 2015 Mar 17.

4.

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function.

Etherton M, Földy C, Sharma M, Tabuchi K, Liu X, Shamloo M, Malenka RC, Südhof TC.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13764-9. doi: 10.1073/pnas.1111093108. Epub 2011 Aug 1.

5.

Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling.

Arons MH, Thynne CJ, Grabrucker AM, Li D, Schoen M, Cheyne JE, Boeckers TM, Montgomery JM, Garner CC.

J Neurosci. 2012 Oct 24;32(43):14966-78. doi: 10.1523/JNEUROSCI.2215-12.2012.

6.

Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling.

Speed HE, Masiulis I, Gibson JR, Powell CM.

PLoS One. 2015 Oct 15;10(10):e0140638. doi: 10.1371/journal.pone.0140638. eCollection 2015.

7.

Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.

Rothwell PE, Fuccillo MV, Maxeiner S, Hayton SJ, Gokce O, Lim BK, Fowler SC, Malenka RC, Südhof TC.

Cell. 2014 Jul 3;158(1):198-212. doi: 10.1016/j.cell.2014.04.045.

8.

[Synapse maturation and autism: learning from neuroligin model mice].

Tabuchi K, Chang W, Asgar NF, Pramanik G.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2014 Feb;34(1):1-4. Review. Japanese. Erratum in: Nihon Shinkei Seishin Yakurigaku Zasshi. 2015 Jun;35(3):79. Hang, WenHsin [corrected to Chang, WenHsin]; Asgar, Nur Farehan Mohamed [corrected to Asgar, Nur Farehan].

PMID:
25069265
9.

Altered synchrony and connectivity in neuronal networks expressing an autism-related mutation of neuroligin 3.

Gutierrez RC, Hung J, Zhang Y, Kertesz AC, Espina FJ, Colicos MA.

Neuroscience. 2009 Aug 4;162(1):208-21. doi: 10.1016/j.neuroscience.2009.04.062. Epub 2009 May 3.

PMID:
19406211
10.

Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling.

Földy C, Malenka RC, Südhof TC.

Neuron. 2013 May 8;78(3):498-509. doi: 10.1016/j.neuron.2013.02.036. Epub 2013 Apr 11.

11.

Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds.

Mondin M, Labrousse V, Hosy E, Heine M, Tessier B, Levet F, Poujol C, Blanchet C, Choquet D, Thoumine O.

J Neurosci. 2011 Sep 21;31(38):13500-15. doi: 10.1523/JNEUROSCI.6439-10.2011.

12.

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice.

Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Südhof TC.

Science. 2007 Oct 5;318(5847):71-6. Epub 2007 Sep 6.

13.

Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism.

Chubykin AA, Liu X, Comoletti D, Tsigelny I, Taylor P, Südhof TC.

J Biol Chem. 2005 Jun 10;280(23):22365-74. Epub 2005 Mar 29.

14.

Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1.

Pak C, Danko T, Zhang Y, Aoto J, Anderson G, Maxeiner S, Yi F, Wernig M, Südhof TC.

Cell Stem Cell. 2015 Sep 3;17(3):316-28. doi: 10.1016/j.stem.2015.07.017. Epub 2015 Aug 13.

15.

Homodimerization and isoform-specific heterodimerization of neuroligins.

Poulopoulos A, Soykan T, Tuffy LP, Hammer M, Varoqueaux F, Brose N.

Biochem J. 2012 Sep 1;446(2):321-30. doi: 10.1042/BJ20120808.

PMID:
22671294
16.

Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts.

Heine M, Thoumine O, Mondin M, Tessier B, Giannone G, Choquet D.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20947-52. doi: 10.1073/pnas.0804007106. Epub 2008 Dec 19.

17.

Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter.

Nam CI, Chen L.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6137-42. Epub 2005 Apr 18.

18.

The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo.

Soler-Llavina GJ, Fuccillo MV, Ko J, Südhof TC, Malenka RC.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16502-9. doi: 10.1073/pnas.1114028108. Epub 2011 Sep 27.

19.
20.

Investigating synapse formation and function using human pluripotent stem cell-derived neurons.

Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3005-10. doi: 10.1073/pnas.1007753108. Epub 2011 Jan 28.

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