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Items: 1 to 20 of 109

1.

Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist.

Falck E, Begrow F, Verspohl E, Wünsch B.

J Pharm Biomed Anal. 2014 Jan;88:96-105. doi: 10.1016/j.jpba.2013.08.014. Epub 2013 Aug 21.

PMID:
24042122
2.

In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist.

Falck E, Begrow F, Verspohl EJ, Wünsch B.

J Pharm Biomed Anal. 2014 Jun;94:36-44. doi: 10.1016/j.jpba.2014.01.017. Epub 2014 Jan 24.

PMID:
24534302
4.

Metabolism, distribution and excretion of a selective N-methyl-D-aspartate receptor antagonist, traxoprodil, in rats and dogs.

Prakash C, Cui D, Potchoiba MJ, Butler T.

Drug Metab Dispos. 2007 Aug;35(8):1350-64. Epub 2007 May 11.

6.

Synthesis and in vitro characterisation of ifenprodil-based fluorescein conjugates as GluN1/GluN2B N-Methyl-D-aspartate receptor antagonists.

Dhilly M, Becerril-Ortega J, Colloc'h N, MacKenzie ET, Barré L, Buisson A, Nicole O, Perrio C.

Chembiochem. 2013 Apr 15;14(6):759-69. doi: 10.1002/cbic.201200675. Epub 2013 Mar 26.

PMID:
23532918
7.

Comparison of the ex vivo receptor occupancy profile of ketamine to several NMDA receptor antagonists in mouse hippocampus.

Lord B, Wintmolders C, Langlois X, Nguyen L, Lovenberg T, Bonaventure P.

Eur J Pharmacol. 2013 Sep 5;715(1-3):21-5. doi: 10.1016/j.ejphar.2013.06.028. Epub 2013 Jul 16.

PMID:
23872376
9.

Separation of alpha 1 adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds.

Chenard BL, Shalaby IA, Koe BK, Ronau RT, Butler TW, Prochniak MA, Schmidt AW, Fox CB.

J Med Chem. 1991 Oct;34(10):3085-90.

PMID:
1681106
10.

Mapping the high-affinity binding domain of 5-substituted benzimidazoles to the proximal N-terminus of the GluN2B subunit of the NMDA receptor.

Wee XK, Ng KS, Leung HW, Cheong YP, Kong KH, Ng FM, Soh W, Lam Y, Low CM.

Br J Pharmacol. 2010 Jan 1;159(2):449-61. doi: 10.1111/j.1476-5381.2009.00549.x. Epub 2010 Jan 15.

12.

Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.

Karakas E, Simorowski N, Furukawa H.

Nature. 2011 Jun 15;475(7355):249-53. doi: 10.1038/nature10180.

13.

Ifenprodil effects on GluN2B-containing glutamate receptors.

Amico-Ruvio SA, Paganelli MA, Myers JM, Popescu GK.

Mol Pharmacol. 2012 Dec;82(6):1074-81. doi: 10.1124/mol.112.078998. Epub 2012 Aug 30.

14.
15.

Enhancement of NMDA-induced current by the putative NR2B selective antagonist ifenprodil.

Zhang XX, Bunney BS, Shi WX.

Synapse. 2000 Jul;37(1):56-63.

PMID:
10842351
16.

[3H]ifenprodil binding to NMDA receptors in porcine hippocampal brain membranes.

Höfner G, Wanner KT.

Eur J Pharmacol. 2000 Apr 14;394(2-3):211-9.

PMID:
10771286
17.

Effect of ifenprodil on GluN1/GluN2B N-methyl-D-aspartate receptor gating.

Bhatt JM, Prakash A, Suryavanshi PS, Dravid SM.

Mol Pharmacol. 2013 Jan;83(1):9-21. doi: 10.1124/mol.112.080952. Epub 2012 Sep 24.

18.

In vitro and in vivo phase II metabolism of combretastatin A-4: evidence for the formation of a sulphate conjugate metabolite.

Aprile S, Del Grosso E, Grosa G.

Xenobiotica. 2009 Feb;39(2):148-61. doi: 10.1080/00498250802566976.

PMID:
19255941
19.

Synaptic NMDA receptors in basolateral amygdala principal neurons are triheteromeric proteins: physiological role of GluN2B subunits.

Delaney AJ, Sedlak PL, Autuori E, Power JM, Sah P.

J Neurophysiol. 2013 Mar;109(5):1391-402. doi: 10.1152/jn.00176.2012. Epub 2012 Dec 5.

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