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Items: 1 to 20 of 97

1.

Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways.

Suntharalingam K, Johnstone TC, Bruno PM, Lin W, Hemann MT, Lippard SJ.

J Am Chem Soc. 2013 Sep 25;135(38):14060-3. doi: 10.1021/ja4075375. Epub 2013 Sep 16.

2.

Synthesis, characterization, and antitumor activity of unusual pseudo five coordinate gold(III) complexes: distinct cytotoxic mechanism or expensive ligand delivery systems?

Olsen PM, Ruiz C, Lussier D, Le BK, Angel N, Smith M, Hwang CB, Khatib R, Jenkins J, Adams K, Getcher J, Tham F, Chen ZG, Wilson EH, Eichler JF.

J Inorg Biochem. 2014 Dec;141:121-131. doi: 10.1016/j.jinorgbio.2014.08.014. Epub 2014 Sep 6.

PMID:
25243390
3.

Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling.

Zhao Z, Luo Z, Wu Q, Zheng W, Feng Y, Chen T.

Dalton Trans. 2014 Dec 7;43(45):17017-28. doi: 10.1039/c4dt01392a.

PMID:
25087850
4.

Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands.

Tang Q, Ni WX, Leung CF, Man WL, Lau KK, Liang Y, Lam YW, Wong WY, Peng SM, Liu GJ, Lau TC.

Chem Commun (Camb). 2013 Nov 4;49(85):9980-2. doi: 10.1039/c3cc42250j.

PMID:
24042270
5.

A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex.

Suntharalingam K, Lin W, Johnstone TC, Bruno PM, Zheng YR, Hemann MT, Lippard SJ.

J Am Chem Soc. 2014 Oct 15;136(41):14413-6. doi: 10.1021/ja508808v. Epub 2014 Oct 6.

6.

Microwave synthesis of mixed ligand diimine-thiosemicarbazone complexes of ruthenium(II): biophysical reactivity and cytotoxicity.

Beckford FA, Shaloski M Jr, Leblanc G, Thessing J, Lewis-Alleyne LC, Holder AA, Li L, Seeram NP.

Dalton Trans. 2009 Dec 28;(48):10757-64. doi: 10.1039/b915081a. Epub 2009 Sep 28.

7.

Mixed ligand copper(II) complexes of N,N-bis(benzimidazol-2-ylmethyl)amine (BBA) with diimine co-ligands: efficient chemical nuclease and protease activities and cytotoxicity.

Loganathan R, Ramakrishnan S, Suresh E, Riyasdeen A, Akbarsha MA, Palaniandavar M.

Inorg Chem. 2012 May 21;51(10):5512-32. doi: 10.1021/ic2017177. Epub 2012 May 4.

PMID:
22559171
8.

Synthesis, Characterization, and in Vitro Antitumor Activity of Ruthenium(II) Polypyridyl Complexes Tethering EGFR-Inhibiting 4-Anilinoquinazolines.

Du J, Kang Y, Zhao Y, Zheng W, Zhang Y, Lin Y, Wang Z, Wang Y, Luo Q, Wu K, Wang F.

Inorg Chem. 2016 May 2;55(9):4595-605. doi: 10.1021/acs.inorgchem.6b00309. Epub 2016 Apr 19.

PMID:
27093574
9.

Luminescent ruthenium complexes for theranostic applications.

Cardoso CR, Lima MV, Cheleski J, Peterson EJ, Venâncio T, Farrell NP, Carlos RM.

J Med Chem. 2014 Jun 12;57(11):4906-15. doi: 10.1021/jm5005946. Epub 2014 May 29.

PMID:
24831959
10.

Cytotoxicity, apoptosis, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential, and Western blotting analysis of ruthenium(II) complexes.

Lin GJ, Jiang GB, Xie YY, Huang HL, Liang ZH, Liu YJ.

J Biol Inorg Chem. 2013 Dec;18(8):873-82. doi: 10.1007/s00775-013-1032-2. Epub 2013 Aug 30.

PMID:
23989405
11.

DNA binding, antitumor activities, and hydroxyl radical scavenging properties of novel oxovanadium (IV) complexes with substituted isoniazid.

Liao X, Lu J, Ying P, Zhao P, Bai Y, Li W, Liu M.

J Biol Inorg Chem. 2013 Dec;18(8):975-84.

PMID:
24077688
12.

Rhenium(IV) compounds inducing apoptosis in cancer cells.

Martínez-Lillo J, Mastropietro TF, Lappano R, Madeo A, Alberto ME, Russo N, Maggiolini M, De Munno G.

Chem Commun (Camb). 2011 May 14;47(18):5283-5. doi: 10.1039/c1cc11038a. Epub 2011 Mar 29.

PMID:
21448489
13.

Synthesis, cellular uptake, apopotosis, cytotoxicity, cell cycle arrest, interaction with DNA and antioxidant activity of ruthenium(II) complexes.

Huang HL, Li ZZ, Liang ZH, Yao JH, Liu YJ.

Eur J Med Chem. 2011 Aug;46(8):3282-90. doi: 10.1016/j.ejmech.2011.04.049. Epub 2011 Apr 29.

PMID:
21570748
14.

Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies.

Luís DV, Silva J, Tomaz AI, de Almeida RF, Larguinho M, Baptista PV, Martins LM, Silva TF, Borralho PM, Rodrigues CM, Rodrigues AS, Pombeiro AJ, Fernandes AR.

J Biol Inorg Chem. 2014 Aug;19(6):787-803. doi: 10.1007/s00775-014-1110-0. Epub 2014 Jan 31.

PMID:
24481501
15.

Unsymmetrical oxovanadium complexes derived from salicylaldehyde and phenanthroline: synthesis, DNA interactions, and antitumor activities.

Liao X, Pan W, He R, Guo H, Ying P, Lu J.

Chem Biol Drug Des. 2014 Mar;83(3):367-78. doi: 10.1111/cbdd.12248. Epub 2013 Dec 26.

PMID:
24118856
16.

Efficient DNA cleavage mediated by mononuclear mixed ligand copper(II) phenolate complexes: the role of co-ligand planarity on DNA binding and cleavage and anticancer activity.

Jaividhya P, Dhivya R, Akbarsha MA, Palaniandavar M.

J Inorg Biochem. 2012 Sep;114:94-105. doi: 10.1016/j.jinorgbio.2012.04.018. Epub 2012 May 8.

PMID:
22841366
17.

Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.

Wu J, Chen W, Yin Y, Zheng Z, Zou G.

Biometals. 2014 Jun;27(3):445-58. doi: 10.1007/s10534-014-9710-2. Epub 2014 Mar 18.

PMID:
24638265
18.

A SAR study of novel antiproliferative ruthenium and osmium complexes with quinoxalinone ligands in human cancer cell lines.

Ginzinger W, Mühlgassner G, Arion VB, Jakupec MA, Roller A, Galanski M, Reithofer M, Berger W, Keppler BK.

J Med Chem. 2012 Apr 12;55(7):3398-413. doi: 10.1021/jm3000906. Epub 2012 Mar 27.

PMID:
22417128
19.

Synthesis, characterization; DNA binding and antitumor activity of ruthenium(II) polypyridyl complexes.

Srishailam A, Gabra NM, Kumar YP, Reddy KL, Devi CS, Anil Kumar D, Singh SS, Satyanarayana S.

J Photochem Photobiol B. 2014 Dec;141:47-58. doi: 10.1016/j.jphotobiol.2014.09.003. Epub 2014 Sep 16.

PMID:
25318017
20.

Synthesis, characterization and anticancer activity studies of ruthenium(II) polypyridyl complexes on A549 cells.

Zeng CC, Jiang GB, Lai SH, Zhang C, Yin H, Tang B, Wan D, Liu YJ.

J Photochem Photobiol B. 2016 Aug;161:295-303. doi: 10.1016/j.jphotobiol.2016.06.004. Epub 2016 Jun 5.

PMID:
27288660

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