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Items: 1 to 20 of 103


Effects of brain IKKβ gene silencing by small interfering RNA on P-glycoprotein expression and brain damage in the rat kainic acid-induced seizure model.

Yu N, Liu H, Zhang YF, Su LY, Liu XH, Li LC, Hao JB, Huang XJ, Di Q.

CNS Neurol Disord Drug Targets. 2014;13(4):661-72.


Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats.

Yu N, Di Q, Liu H, Hu Y, Jiang Y, Yan YK, Zhang YF, Zhang YD.

Mediators Inflamm. 2011;2011:670613. doi: 10.1155/2011/670613. Epub 2011 Feb 21.


Small interfering RNA targeting IKKβ prevents renal ischemia-reperfusion injury in rats.

Wan X, Fan L, Hu B, Yang J, Li X, Chen X, Cao C.

Am J Physiol Renal Physiol. 2011 Apr;300(4):F857-63. doi: 10.1152/ajprenal.00547.2010. Epub 2011 Feb 2.


Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon's capsule fibroblasts in vitro.

Duan Y, Guan X, Ge J, Quan D, Zhuo Y, Ye H, Shao T.

Mol Vis. 2008;14:2616-28. Epub 2008 Dec 31.


Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-κB activation-induced nitric oxide synthase II expression.

Chang CC, Chen SD, Lin TK, Chang WN, Liou CW, Chang AY, Chan SH, Chuang YC.

Neurobiol Dis. 2014 Feb;62:241-9. doi: 10.1016/j.nbd.2013.10.012. Epub 2013 Oct 16.


HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products.

Chen Y, Huang XJ, Yu N, Xie Y, Zhang K, Wen F, Liu H, Di Q.

PLoS One. 2015 Oct 20;10(10):e0140918. doi: 10.1371/journal.pone.0140918. eCollection 2015.


Small interfering RNA targeting nuclear factor kappa B to prevent vein graft stenosis in rat models.

Meng XB, Bi XL, Zhao HL, Feng JB, Zhang JP, Song GM, Sun WY, Bi YW.

Transplant Proc. 2013 Jul-Aug;45(6):2553-8. doi: 10.1016/j.transproceed.2013.03.045.


Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway.

Zhang HL, Xu M, Wei C, Qin AP, Liu CF, Hong LZ, Zhao XY, Liu J, Qin ZH.

Neuroscience. 2011 Mar 10;176:381-95. doi: 10.1016/j.neuroscience.2010.12.029. Epub 2010 Dec 24.


Activation of both nuclear factor of activated T cells and inhibitor of nuclear factor-kappa B kinase beta-subunit-/nuclear factor-kappa B is critical for cyclooxygenase-2 induction by benzo[a]pyrene in human bronchial epithelial cells.

Ding J, Wu K, Zhang D, Luo W, Li J, Ouyang W, Song L, Huang C.

Cancer Sci. 2007 Sep;98(9):1323-9. Epub 2007 Jul 19. Erratum in: Cancer Sci. 2009 Nov;100(11):2234.


Pregnane X Receptor Not Nuclear Factor-kappa B Up-regulates P-glycoprotein Expression in the Brain of Chronic Epileptic Rats Induced by Kainic Acid.

Yu N, Zhang YF, Zhang K, Cheng YF, Ma HY, Di Q.

Neurochem Res. 2017 Aug;42(8):2167-2177. doi: 10.1007/s11064-017-2224-x. Epub 2017 Mar 16.


Anti-fibrotic effects of specific-siRNA targeting of the receptor for advanced glycation end products in a rat model of experimental hepatic fibrosis.

Cai XG, Xia JR, Li WD, Lu FL, Liu J, Lu Q, Zhi H.

Mol Med Rep. 2014 Jul;10(1):306-14. doi: 10.3892/mmr.2014.2207. Epub 2014 May 2.


IKKβ regulates endothelial thrombomodulin in a Klf2-dependent manner.

Pathak R, Shao L, Chafekar SM, Feng W, Ponnappan U, Fink LM, Zhou D, Hauer-Jensen M.

J Thromb Haemost. 2014 Sep;12(9):1533-1544. doi: 10.1111/jth.12664. Epub 2014 Aug 11.


IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.

Adli M, Merkhofer E, Cogswell P, Baldwin AS.

PLoS One. 2010 Feb 25;5(2):e9428. doi: 10.1371/journal.pone.0009428.


Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation.

Lubin FD, Ren Y, Xu X, Anderson AE.

J Neurochem. 2007 Nov;103(4):1381-95. Epub 2007 Aug 28.


Bidirectional regulation of nuclear factor-κB and mammalian target of rapamycin signaling functionally links Bnip3 gene repression and cell survival of ventricular myocytes.

Dhingra R, Gang H, Wang Y, Biala AK, Aviv Y, Margulets V, Tee A, Kirshenbaum LA.

Circ Heart Fail. 2013 Mar;6(2):335-43. doi: 10.1161/CIRCHEARTFAILURE.112.000061. Epub 2013 Feb 8.


Enterovirus 71 2C protein inhibits TNF-α-mediated activation of NF-κB by suppressing IκB kinase β phosphorylation.

Zheng Z, Li H, Zhang Z, Meng J, Mao D, Bai B, Lu B, Mao P, Hu Q, Wang H.

J Immunol. 2011 Sep 1;187(5):2202-12. doi: 10.4049/jimmunol.1100285. Epub 2011 Aug 1.


siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.

Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A.

Diabetes. 2008 Aug;57(8):2066-73. doi: 10.2337/db07-0763. Epub 2008 Apr 28.


Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK/NF-kappaB signaling.

Widera D, Mikenberg I, Elvers M, Kaltschmidt C, Kaltschmidt B.

BMC Neurosci. 2006 Sep 20;7:64.


Hyperammonemia enhances the function and expression of P-glycoprotein and Mrp2 at the blood-brain barrier through NF-κB.

Zhang J, Zhang M, Sun B, Li Y, Xu P, Liu C, Liu L, Liu X.

J Neurochem. 2014 Dec;131(6):791-802. doi: 10.1111/jnc.12944. Epub 2014 Sep 26.

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