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Items: 1 to 20 of 104

1.

53BP1 sensitizes breast cancer cells to 5-fluorouracil.

Li X, Kong X, Kong X, Wang Y, Yan S, Yang Q.

PLoS One. 2013 Sep 6;8(9):e74928. doi: 10.1371/journal.pone.0074928.

2.

MicroRNA-494 sensitizes colon cancer cells to fluorouracil through regulation of DPYD.

Chai J, Dong W, Xie C, Wang L, Han DL, Wang S, Guo HL, Zhang ZL.

IUBMB Life. 2015 Mar;67(3):191-201. doi: 10.1002/iub.1361.

3.

Positive interaction between lapatinib and capecitabine in human breast cancer models: study of molecular determinants.

Chefrour M, Milano G, Formento P, Giacometti S, Denden A, Renée N, Iliadis A, Fischel JL, Ciccolini J.

Fundam Clin Pharmacol. 2012 Aug;26(4):530-7. doi: 10.1111/j.1472-8206.2011.00945.x.

PMID:
21623901
4.

Prognostic significance of 5-fluorouracil metabolism-relating enzymes and enhanced chemosensitivity to 5-fluorouracil by 5-chloro 2,4-dihydroxy-pyridine in urothelial carcinoma.

Ide H, Kikuchi E, Hasegawa M, Kozakai N, Kosaka T, Miyajima A, Oya M.

BMC Cancer. 2012 Sep 22;12:420. doi: 10.1186/1471-2407-12-420.

5.

The role of thymidylate synthase and dihydropyrimidine dehydrogenase in resistance to 5-fluorouracil in human lung cancer cells.

Oguri T, Achiwa H, Bessho Y, Muramatsu H, Maeda H, Niimi T, Sato S, Ueda R.

Lung Cancer. 2005 Sep;49(3):345-51.

PMID:
15993511
7.

The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III.

Jiang H, Dong Q, Luo X, Shi B, Wang H, Gao H, Kong J, Zhang J, Li Z.

Cancer Lett. 2014 Jan 1;342(1):113-20. doi: 10.1016/j.canlet.2013.08.038.

PMID:
24007863
8.

Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil.

Vinod BS, Antony J, Nair HH, Puliyappadamba VT, Saikia M, Narayanan SS, Bevin A, Anto RJ.

Cell Death Dis. 2013 Feb 21;4:e505. doi: 10.1038/cddis.2013.26.

9.

Identification of genes conferring resistance to 5-fluorouracil.

Yoo BK, Gredler R, Vozhilla N, Su ZZ, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher PB, Sarkar D.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12938-43. doi: 10.1073/pnas.0901451106.

10.

Intratumoural thymidylate synthase and dihydropyrimidine dehydrogenase activities are good predictors of 5-fluorouracil sensitivity in colorectal cancer.

Ishibiki Y, Kitajima M, Sakamoto K, Tomiki Y, Sakamoto S, Kamano T.

J Int Med Res. 2003 May-Jun;31(3):181-7.

PMID:
12870370
11.

Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer.

Okumura K, Shiomi H, Mekata E, Kaizuka M, Endo Y, Kurumi Y, Tani T.

Oncol Rep. 2006 Apr;15(4):875-82.

PMID:
16525674
12.

Thymidylate synthase predicts for clinical outcome in invasive breast cancer.

Yu Z, Sun J, Zhen J, Zhang Q, Yang Q.

Histol Histopathol. 2005 Jul;20(3):871-8.

PMID:
15944938
13.

A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil.

Beck A, Etienne MC, Chéradame S, Fischel JL, Formento P, Renée N, Milano G.

Eur J Cancer. 1994;30A(10):1517-22.

PMID:
7833111
14.

Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in breast cancer predicts 5-FU sensitivity by a histocultural drug sensitivity test.

Kakimoto M, Uetake H, Osanai T, Shirota Y, Takagi Y, Takeshita E, Toriya Y, Danenberg K, Danenberg PV, Sugihara K.

Cancer Lett. 2005 Jun 1;223(1):103-11.

PMID:
15890242
15.
16.

53BP1 functions as a tumor suppressor in breast cancer via the inhibition of NF-κB through miR-146a.

Li X, Xu B, Moran MS, Zhao Y, Su P, Haffty BG, Shao C, Yang Q.

Carcinogenesis. 2012 Dec;33(12):2593-600. doi: 10.1093/carcin/bgs298.

17.

Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer.

Terashima M, Fujiwara H, Takagane A, Abe K, Irinoda T, Nakaya T, Yonezawa H, Oyama K, Saito K, Kanzaki N, Ohtani S, Nemoto T, Hoshino Y, Kogure M, Gotoh M.

Gastric Cancer. 2003;6 Suppl 1:71-81.

PMID:
12775024
18.

The upregulation of dihydropyrimidine dehydrogenase in liver is involved in acquired resistance to 5-fluorouracil.

Li LH, Dong H, Zhao F, Tang J, Chen X, Ding J, Men HT, Luo WX, Du Y, Ge J, Tan BX, Cao D, Liu JY.

Eur J Cancer. 2013 May;49(7):1752-60. doi: 10.1016/j.ejca.2012.12.013.

PMID:
23313143
19.

Suppression of heat shock protein 27 expression promotes 5-fluorouracil sensitivity in colon cancer cells in a xenograft model.

Hayashi R, Ishii Y, Ochiai H, Matsunaga A, Endo T, Hasegawa H, Kitagawa Y.

Oncol Rep. 2012 Oct;28(4):1269-74. doi: 10.3892/or.2012.1935.

PMID:
22842517
20.

Combined therapy with a thymidylate synthase-inhibiting vector and S-1 has effective antitumor activity against 5-FU-resistant tumors.

Kadota K, Huang CL, Liu D, Yokomise H, Haba R, Wada H.

Int J Oncol. 2011 Feb;38(2):355-63. doi: 10.3892/ijo.2010.880.

PMID:
21174056
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