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Items: 1 to 20 of 107

1.

C22:0- and C24:0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines.

Holliday MW Jr, Cox SB, Kang MH, Maurer BJ.

PLoS One. 2013 Sep 9;8(9):e74768. doi: 10.1371/journal.pone.0074768. eCollection 2013.

2.

N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing.

Wang H, Maurer BJ, Liu YY, Wang E, Allegood JC, Kelly S, Symolon H, Liu Y, Merrill AH Jr, Gouazé-Andersson V, Yu JY, Giuliano AE, Cabot MC.

Mol Cancer Ther. 2008 Sep;7(9):2967-76. doi: 10.1158/1535-7163.MCT-08-0549.

3.

Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms.

Casasampere M, Ordóñez YF, Casas J, Fabrias G.

Biochim Biophys Acta. 2017 Feb;1861(2):264-275. doi: 10.1016/j.bbagen.2016.11.033. Epub 2016 Nov 25.

PMID:
27894925
4.

Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy.

Gagliostro V, Casas J, Caretti A, Abad JL, Tagliavacca L, Ghidoni R, Fabrias G, Signorelli P.

Int J Biochem Cell Biol. 2012 Dec;44(12):2135-43. doi: 10.1016/j.biocel.2012.08.025. Epub 2012 Sep 7.

PMID:
22960157
5.

Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death.

Apraiz A, Idkowiak-Baldys J, Nieto-Rementería N, Boyano MD, Hannun YA, Asumendi A.

Biochem Cell Biol. 2012 Apr;90(2):209-23. doi: 10.1139/o2012-001. Epub 2012 Mar 19.

6.

Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells.

Ridgway ND, Merriam DL.

Biochim Biophys Acta. 1995 Apr 28;1256(1):57-70.

PMID:
7742357
7.

Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells.

Kraveka JM, Li L, Szulc ZM, Bielawski J, Ogretmen B, Hannun YA, Obeid LM, Bielawska A.

J Biol Chem. 2007 Jun 8;282(23):16718-28. Epub 2007 Feb 5.

8.

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.

Signorelli P, Munoz-Olaya JM, Gagliostro V, Casas J, Ghidoni R, Fabriàs G.

Cancer Lett. 2009 Sep 18;282(2):238-43. doi: 10.1016/j.canlet.2009.03.020. Epub 2009 Apr 25.

PMID:
19394759
9.

Quantitative analysis of ceramide molecular species by high performance liquid chromatography.

Yano M, Kishida E, Muneyuki Y, Masuzawa Y.

J Lipid Res. 1998 Oct;39(10):2091-8.

10.

Effects of sphingoid bases on the sphingolipidome in early keratinocyte differentiation.

Sigruener A, Tarabin V, Paragh G, Liebisch G, Koehler T, Farwick M, Schmitz G.

Exp Dermatol. 2013 Oct;22(10):677-9. doi: 10.1111/exd.12231.

PMID:
24079743
11.

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells.

Mao Z, Sun W, Xu R, Novgorodov S, Szulc ZM, Bielawski J, Obeid LM, Mao C.

J Biol Chem. 2010 Sep 17;285(38):29078-90. doi: 10.1074/jbc.M110.105296. Epub 2010 Jul 13.

14.
15.

Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells.

Apraiz A, Idkowiak-Baldys JK, Boyano MD, Pérez-Yarza G, Hannun YA, Asumendi A.

BMC Cancer. 2011 Nov 7;11:477. doi: 10.1186/1471-2407-11-477.

16.

Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells.

Breen P, Joseph N, Thompson K, Kraveka JM, Gudz TI, Li L, Rahmaniyan M, Bielawski J, Pierce JS, VAN Buren E, Bhatti G, Separovic D.

Anticancer Res. 2013 Jan;33(1):77-84.

17.

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide.

Michel C, van Echten-Deckert G, Rother J, Sandhoff K, Wang E, Merrill AH Jr.

J Biol Chem. 1997 Sep 5;272(36):22432-7.

18.

Cell density-dependent reduction of dihydroceramide desaturase activity in neuroblastoma cells.

Spassieva SD, Rahmaniyan M, Bielawski J, Clarke CJ, Kraveka JM, Obeid LM.

J Lipid Res. 2012 May;53(5):918-28. doi: 10.1194/jlr.M019075. Epub 2012 Feb 29.

19.

Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism.

Maurer BJ, Melton L, Billups C, Cabot MC, Reynolds CP.

J Natl Cancer Inst. 2000 Dec 6;92(23):1897-909.

PMID:
11106681
20.

Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide.

Jiang Q, Rao X, Kim CY, Freiser H, Zhang Q, Jiang Z, Li G.

Int J Cancer. 2012 Feb 1;130(3):685-93. doi: 10.1002/ijc.26054. Epub 2011 May 9.

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