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Items: 1 to 20 of 97


Targeting gastrin-releasing peptide suppresses neuroblastoma progression via upregulation of PTEN signaling.

Paul P, Qiao J, Kim KW, Romain C, Lee S, Volny N, Mobley B, Correa H, Chung DH.

PLoS One. 2013 Sep 9;8(9):e72570. doi: 10.1371/journal.pone.0072570. eCollection 2013.


Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma.

Qiao J, Kang J, Ishola TA, Rychahou PG, Evers BM, Chung DH.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12891-6. doi: 10.1073/pnas.0711861105. Epub 2008 Aug 27.


Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells.

Kim KW, Paul P, Qiao J, Lee S, Chung DH.

Autophagy. 2013 Oct;9(10):1579-90. doi: 10.4161/auto.25987. Epub 2013 Aug 29.


Phosphatidylinositol 3-kinase regulation of gastrin-releasing peptide-induced cell cycle progression in neuroblastoma cells.

Ishola TA, Kang J, Qiao J, Evers BM, Chung DH.

Biochim Biophys Acta. 2007 Jun;1770(6):927-32. Epub 2007 Feb 20.


FAK is a critical regulator of neuroblastoma liver metastasis.

Lee S, Qiao J, Paul P, O'Connor KL, Evers MB, Chung DH.

Oncotarget. 2012 Dec;3(12):1576-87.


Akt2 regulates metastatic potential in neuroblastoma.

Qiao J, Lee S, Paul P, Qiao L, Taylor CJ, Schlegel C, Colon NC, Chung DH.

PLoS One. 2013;8(2):e56382. doi: 10.1371/journal.pone.0056382. Epub 2013 Feb 26.


Differential regulation of cyclin-dependent kinase inhibitors in neuroblastoma cells.

Qiao L, Paul P, Lee S, Qiao J, Wang Y, Chung DH.

Biochem Biophys Res Commun. 2013 May 31;435(2):295-9. doi: 10.1016/j.bbrc.2013.04.023. Epub 2013 Apr 22.


Bombesin induces angiogenesis and neuroblastoma growth.

Kang J, Ishola TA, Baregamian N, Mourot JM, Rychahou PG, Evers BM, Chung DH.

Cancer Lett. 2007 Aug 18;253(2):273-81. Epub 2007 Mar 26.


Targeting gastrin-releasing peptide as a new approach to treat aggressive refractory neuroblastomas.

Paul P, Gillory LA, Kang J, Qiao J, Chung DH.

Surgery. 2011 Mar;149(3):425-32. doi: 10.1016/j.surg.2010.08.011. Epub 2010 Oct 29.


Integrin β1 is critical for gastrin-releasing peptide receptor-mediated neuroblastoma cell migration and invasion.

Lee S, Qiao J, Paul P, Chung DH.

Surgery. 2013 Aug;154(2):369-75. doi: 10.1016/j.surg.2013.04.067.


PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.

Fang J, Ding M, Yang L, Liu LZ, Jiang BH.

Cell Signal. 2007 Dec;19(12):2487-97. Epub 2007 Aug 15.


SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT.

Bhoopathi P, Gorantla B, Sailaja GS, Gondi CS, Gujrati M, Klopfenstein JD, Rao JS.

PLoS One. 2012;7(5):e36093. doi: 10.1371/journal.pone.0036093. Epub 2012 May 2.


KLF5 inhibits angiogenesis in PTEN-deficient prostate cancer by attenuating AKT activation and subsequent HIF1α accumulation.

Ci X, Xing C, Zhang B, Zhang Z, Ni JJ, Zhou W, Dong JT.

Mol Cancer. 2015 Apr 21;14:91. doi: 10.1186/s12943-015-0365-6.


Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma.

Gorantla B, Bhoopathi P, Chetty C, Gogineni VR, Sailaja GS, Gondi CS, Rao JS.

Angiogenesis. 2013 Jan;16(1):85-100. doi: 10.1007/s10456-012-9301-1. Epub 2012 Sep 6.


PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway.

Tian T, Nan KJ, Guo H, Wang WJ, Ruan ZP, Wang SH, Liang X, Lu CX.

Oncol Rep. 2010 Jun;23(6):1593-600.


PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuroblastoma cells.

Crosswell HE, Dasgupta A, Alvarado CS, Watt T, Christensen JG, De P, Durden DL, Findley HW.

BMC Cancer. 2009 Nov 25;9:411. doi: 10.1186/1471-2407-9-411.


Gastrin-releasing peptide is a growth factor for human neuroblastomas.

Kim S, Hu W, Kelly DR, Hellmich MR, Evers BM, Chung DH.

Ann Surg. 2002 May;235(5):621-9; discussion 629-30.


TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer.

Shih MC, Chen JY, Wu YC, Jan YH, Yang BM, Lu PJ, Cheng HC, Huang MS, Yang CJ, Hsiao M, Lai JM.

Oncogene. 2012 May 10;31(19):2389-400. doi: 10.1038/onc.2011.419. Epub 2011 Sep 26.


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