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Items: 1 to 20 of 99

1.

TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.

Shimada K, Filipuzzi I, Stahl M, Helliwell SB, Studer C, Hoepfner D, Seeber A, Loewith R, Movva NR, Gasser SM.

Mol Cell. 2013 Sep 26;51(6):829-39. doi: 10.1016/j.molcel.2013.08.019.

2.

TOR complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species.

Niles BJ, Powers T.

Mol Biol Cell. 2014 Dec 1;25(24):3962-72. doi: 10.1091/mbc.E14-06-1122.

3.
4.

A role for TOR complex 2 signaling in promoting autophagy.

Vlahakis A, Powers T.

Autophagy. 2014;10(11):2085-6. doi: 10.4161/auto.36262.

5.

TORC2-a new player in genome stability.

Weisman R, Cohen A, Gasser SM.

EMBO Mol Med. 2014 Jul 3;6(8):995-1002. doi: 10.15252/emmm.201403959.

7.

TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy.

Vlahakis A, Graef M, Nunnari J, Powers T.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10586-91. doi: 10.1073/pnas.1406305111.

8.

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.

Mol Cell Biol. 2005 Aug;25(16):7239-48.

9.

TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids.

Muir A, Ramachandran S, Roelants FM, Timmons G, Thorner J.

Elife. 2014 Oct 3;3. doi: 10.7554/eLife.03779.

10.
11.

TORC2 is required to maintain genome stability during S phase in fission yeast.

Schonbrun M, Kolesnikov M, Kupiec M, Weisman R.

J Biol Chem. 2013 Jul 5;288(27):19649-60. doi: 10.1074/jbc.M113.464974.

12.

TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.

Pracheil T, Thornton J, Liu Z.

Genetics. 2012 Apr;190(4):1325-39. doi: 10.1534/genetics.111.138305.

13.
14.

Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases.

Limson MV, Sweder KS.

Toxicol Sci. 2010 Jan;113(1):77-84. doi: 10.1093/toxsci/kfp238.

15.

Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress.

Muir A, Roelants FM, Timmons G, Leskoske KL, Thorner J.

Elife. 2015 Aug 14;4. doi: 10.7554/eLife.09336.

16.

Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulum.

Pracheil T, Liu Z.

J Biol Chem. 2013 Jun 7;288(23):16986-97. doi: 10.1074/jbc.M113.451674.

17.

Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways.

Rispal D, Eltschinger S, Stahl M, Vaga S, Bodenmiller B, Abraham Y, Filipuzzi I, Movva NR, Aebersold R, Helliwell SB, Loewith R.

J Biol Chem. 2015 Jun 12;290(24):14963-78. doi: 10.1074/jbc.M114.627794.

18.

Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae.

Liu Q, Ren T, Fresques T, Oppliger W, Niles BJ, Hur W, Sabatini DM, Hall MN, Powers T, Gray NS.

ACS Chem Biol. 2012 Jun 15;7(6):982-7. doi: 10.1021/cb300058v.

19.

TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation.

Niles BJ, Joslin AC, Fresques T, Powers T.

Cell Rep. 2014 Feb 13;6(3):541-52. doi: 10.1016/j.celrep.2013.12.040. Erratum in: Cell Rep. 2014 Feb 13;6(3):592.

20.

Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway.

Natarajan R, Trivedi-Vyas D, Wairkar YP.

Hum Mol Genet. 2013 May 15;22(10):2010-23. doi: 10.1093/hmg/ddt053.

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