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Items: 1 to 20 of 100

1.

Insulin and IGF1 enhance IL-17-induced chemokine expression through a GSK3B-dependent mechanism: a new target for melatonin's anti-inflammatory action.

Ge D, Dauchy RT, Liu S, Zhang Q, Mao L, Dauchy EM, Blask DE, Hill SM, Rowan BG, Brainard GC, Hanifin JP, Cecil KS, Xiong Z, Myers L, You Z.

J Pineal Res. 2013 Nov;55(4):377-87. doi: 10.1111/jpi.12084. Epub 2013 Aug 20.

2.

AZD5363 Inhibits Inflammatory Synergy between Interleukin-17 and Insulin/Insulin-Like Growth Factor 1.

Chen C, Zhang Q, Liu S, Lambrechts M, Qu Y, You Z.

Front Oncol. 2014 Dec 1;4:343. doi: 10.3389/fonc.2014.00343. eCollection 2014.

3.

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.

Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, Ordog T.

PLoS One. 2013 Oct 7;8(10):e76822. doi: 10.1371/journal.pone.0076822. eCollection 2013.

4.

Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.

Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H.

J Clin Invest. 2008 Jul;118(7):2506-15. doi: 10.1172/JCI35243. Erratum in: J Clin Invest. 2008 Aug;118(8):2986.

5.

[Inhibition of glycogen synthase kinase 3b activity regulates Toll-like receptor 4-mediated liver inflammation].

Ren F, Zhang HY, Piao ZF, Zheng SJ, Chen Y, Chen DX, Duan ZP.

Zhonghua Gan Zang Bing Za Zhi. 2012 Sep;20(9):693-7. doi: 10.3760/cma.j.issn.1007-3418.2012.09.011. Chinese.

PMID:
23207235
6.

Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein.

Sugita H, Kaneki M, Furuhashi S, Hirota M, Takamori H, Baba H.

Mol Cancer Res. 2010 Aug;8(8):1152-63. doi: 10.1158/1541-7786.MCR-09-0472. Epub 2010 Jul 27.

7.

Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen synthesis via a PKCzeta-Akt-GSK3beta pathway in hepatic cells.

Shieh JM, Wu HT, Cheng KC, Cheng JT.

J Pineal Res. 2009 Nov;47(4):339-44. doi: 10.1111/j.1600-079X.2009.00720.x. Epub 2009 Oct 10.

PMID:
19817973
8.

Insulin-like growth factor 1 regulates developing brain glucose metabolism.

Cheng CM, Reinhardt RR, Lee WH, Joncas G, Patel SC, Bondy CA.

Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10236-41.

9.

PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis.

Akundi RS, Zhi L, Büeler H.

Neurobiol Dis. 2012 Jan;45(1):469-78. doi: 10.1016/j.nbd.2011.08.034. Epub 2011 Sep 16.

10.

Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy.

Grassilli E, Narloch R, Federzoni E, Ianzano L, Pisano F, Giovannoni R, Romano G, Masiero L, Leone BE, Bonin S, Donada M, Stanta G, Helin K, Lavitrano M.

Clin Cancer Res. 2013 Jul 15;19(14):3820-31. doi: 10.1158/1078-0432.CCR-12-3289. Epub 2013 May 31.

11.

Inhibition of IGF-1 signaling by genistein: modulation of E-cadherin expression and downregulation of β-catenin signaling in hormone refractory PC-3 prostate cancer cells.

Lee J, Ju J, Park S, Hong SJ, Yoon S.

Nutr Cancer. 2012;64(1):153-62. doi: 10.1080/01635581.2012.630161. Epub 2011 Nov 18.

PMID:
22098108
12.
13.

Stimulation of endothelin-1 gene expression by insulin via phosphoinositide-3 kinase-glycogen synthase kinase-3beta signaling in endothelial cells.

Yang Z, Li JC.

Life Sci. 2008 Feb 27;82(9-10):512-8. doi: 10.1016/j.lfs.2007.12.005. Epub 2007 Dec 17.

PMID:
18201727
14.

Protein breakdown in muscle from burned rats is blocked by insulin-like growth factor i and glycogen synthase kinase-3beta inhibitors.

Fang CH, Li BG, James JH, King JK, Evenson AR, Warden GD, Hasselgren PO.

Endocrinology. 2005 Jul;146(7):3141-9. Epub 2005 Mar 31.

PMID:
15802492
15.

Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model.

Jung-Hynes B, Schmit TL, Reagan-Shaw SR, Siddiqui IA, Mukhtar H, Ahmad N.

J Pineal Res. 2011 Mar;50(2):140-9. doi: 10.1111/j.1600-079X.2010.00823.x. Epub 2010 Nov 9.

16.

GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.

Kapoor M, Liu S, Shi-wen X, Huh K, McCann M, Denton CP, Woodgett JR, Abraham DJ, Leask A.

J Clin Invest. 2008 Oct;118(10):3279-90. doi: 10.1172/JCI35381. Retraction in: J Clin Invest. 2008 Nov;118(11):3812.

17.

IL-17 and insulin/IGF1 enhance adhesion of prostate cancer cells to vascular endothelial cells through CD44-VCAM-1 interaction.

Chen C, Zhang Q, Liu S, Parajuli KR, Qu Y, Mei J, Chen Z, Zhang H, Khismatullin DB, You Z.

Prostate. 2015 Jun;75(8):883-95. doi: 10.1002/pros.22971. Epub 2015 Feb 14.

18.

Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway.

Mao L, Yuan L, Slakey LM, Jones FE, Burow ME, Hill SM.

Breast Cancer Res. 2010;12(6):R107. doi: 10.1186/bcr2794. Epub 2010 Dec 17.

19.
20.

IGF1 dependence of dietary energy balance effects on murine Met1 mammary tumor progression, epithelial-to-mesenchymal transition, and chemokine expression.

Ford NA, Nunez NP, Holcomb VB, Hursting SD.

Endocr Relat Cancer. 2013 Jan 21;20(1):39-51. doi: 10.1530/ERC-12-0329. Print 2013 Feb.

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