Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 121

1.

Cysteine sulfinic acid decarboxylase regulation: A role for farnesoid X receptor and small heterodimer partner in murine hepatic taurine metabolism.

Kerr TA, Matsumoto Y, Matsumoto H, Xie Y, Hirschberger LL, Stipanuk MH, Anakk S, Moore DD, Watanabe M, Kennedy S, Davidson NO.

Hepatol Res. 2014 Oct;44(10):E218-28. doi: 10.1111/hepr.12230. Epub 2013 Oct 18.

2.

Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.

Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS.

Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21.

PMID:
24365583
3.

Dietary cholesterol stimulates CYP7A1 in rats because farnesoid X receptor is not activated.

Xu G, Pan LX, Li H, Shang Q, Honda A, Shefer S, Bollineni J, Matsuzaki Y, Tint GS, Salen G.

Am J Physiol Gastrointest Liver Physiol. 2004 May;286(5):G730-5. Epub 2003 Dec 18.

4.

Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.

Song KH, Li T, Owsley E, Strom S, Chiang JY.

Hepatology. 2009 Jan;49(1):297-305. doi: 10.1002/hep.22627.

5.

Roles of nuclear receptors in the up-regulation of hepatic cholesterol 7alpha-hydroxylase by cholestyramine in rats.

Shibata S, Hayakawa K, Egashira Y, Sanada H.

Life Sci. 2007 Jan 16;80(6):546-53. Epub 2006 Oct 14.

PMID:
17107691
6.

Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genes.

Seok S, Kanamaluru D, Xiao Z, Ryerson D, Choi SE, Suino-Powell K, Xu HE, Veenstra TD, Kemper JK.

J Biol Chem. 2013 Aug 9;288(32):23252-63. doi: 10.1074/jbc.M113.452037. Epub 2013 Jul 3.

7.

FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho.

Fu T, Kim YC, Byun S, Kim DH, Seok S, Suino-Powell K, Xu HE, Kemper B, Kemper JK.

Mol Endocrinol. 2016 Jan;30(1):92-103. doi: 10.1210/me.2015-1226. Epub 2015 Oct 27.

8.

Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.

Chen W, Owsley E, Yang Y, Stroup D, Chiang JY.

J Lipid Res. 2001 Sep;42(9):1402-12.

9.

LXR alpha is the dominant regulator of CYP7A1 transcription.

Gupta S, Pandak WM, Hylemon PB.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):338-43.

PMID:
12054605
10.

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice.

Kong B, Wang L, Chiang JY, Zhang Y, Klaassen CD, Guo GL.

Hepatology. 2012 Sep;56(3):1034-43. doi: 10.1002/hep.25740. Epub 2012 Jul 12.

11.

Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.

Lan T, Rao A, Haywood J, Kock ND, Dawson PA.

J Hepatol. 2012 Aug;57(2):359-65. doi: 10.1016/j.jhep.2012.03.025. Epub 2012 Apr 25.

12.

Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis.

Bechmann LP, Kocabayoglu P, Sowa JP, Sydor S, Best J, Schlattjan M, Beilfuss A, Schmitt J, Hannivoort RA, Kilicarslan A, Rust C, Berr F, Tschopp O, Gerken G, Friedman SL, Geier A, Canbay A.

Hepatology. 2013 Apr;57(4):1394-406. doi: 10.1002/hep.26225.

PMID:
23299969
13.

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism.

Hu X, Bonde Y, Eggertsen G, Rudling M.

J Intern Med. 2014 Jan;275(1):27-38. doi: 10.1111/joim.12140. Epub 2013 Oct 11. Erratum in: J Intern Med. 2015 Jul;278(1):97.

14.

Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.

Kim DH, Kim J, Lee JW.

Mol Endocrinol. 2011 Dec;25(12):2076-83. doi: 10.1210/me.2011-1198. Epub 2011 Oct 27.

15.

Differential regulation of bile acid and cholesterol metabolism by the farnesoid X receptor in Ldlr -/- mice versus hamsters.

Gardès C, Chaput E, Staempfli A, Blum D, Richter H, Benson GM.

J Lipid Res. 2013 May;54(5):1283-99. doi: 10.1194/jlr.M033423. Epub 2013 Feb 21.

16.

Individual bile acids have differential effects on bile acid signaling in mice.

Song P, Rockwell CE, Cui JY, Klaassen CD.

Toxicol Appl Pharmacol. 2015 Feb 15;283(1):57-64. doi: 10.1016/j.taap.2014.12.005. Epub 2015 Jan 9.

PMID:
25582706
17.

Downregulation of hepatic betaine:homocysteine methyltransferase (BHMT) expression in taurine-deficient mice is reversed by taurine supplementation in vivo.

Jurkowska H, Niewiadomski J, Hirschberger LL, Roman HB, Mazor KM, Liu X, Locasale JW, Park E, Stipanuk MH.

Amino Acids. 2016 Mar;48(3):665-76. doi: 10.1007/s00726-015-2108-9. Epub 2015 Oct 20.

18.

Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.

Miao J, Fang S, Lee J, Comstock C, Knudsen KE, Kemper JK.

Mol Cell Biol. 2009 Dec;29(23):6170-81. doi: 10.1128/MCB.00825-09. Epub 2009 Oct 5.

19.

Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064.

Moscovitz JE, Kong B, Buckley K, Buckley B, Guo GL, Aleksunes LM.

Toxicol Appl Pharmacol. 2016 Nov 1;310:60-67. doi: 10.1016/j.taap.2016.08.021. Epub 2016 Sep 5.

PMID:
27609522
20.

Gut microbiota-associated bile acid deconjugation accelerates hepatic steatosis in ob/ob mice.

Park MY, Kim SJ, Ko EK, Ahn SH, Seo H, Sung MK.

J Appl Microbiol. 2016 Sep;121(3):800-10. doi: 10.1111/jam.13158. Epub 2016 Jul 29.

PMID:
27111464

Supplemental Content

Support Center