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Items: 1 to 20 of 162


Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity.

Gaier ED, Miller MB, Ralle M, Aryal D, Wetsel WC, Mains RE, Eipper BA.

J Neurochem. 2013 Dec;127(5):605-19. doi: 10.1111/jnc.12438. Epub 2013 Oct 13.


Pam heterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic function.

Gaier ED, Eipper BA, Mains RE.

Ann N Y Acad Sci. 2014 May;1314:15-23. doi: 10.1111/nyas.12378. Epub 2014 Mar 4.


Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme.

Bonnemaison ML, Bäck N, Duffy ME, Ralle M, Mains RE, Eipper BA.

J Biol Chem. 2015 Aug 28;290(35):21264-79. doi: 10.1074/jbc.M115.641027. Epub 2015 Jul 13.


In vivo and in vitro analyses of amygdalar function reveal a role for copper.

Gaier ED, Rodriguiz RM, Zhou J, Ralle M, Wetsel WC, Eipper BA, Mains RE.

J Neurophysiol. 2014 May;111(10):1927-39. doi: 10.1152/jn.00631.2013. Epub 2014 Feb 19.


Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase.

Steveson TC, Ciccotosto GD, Ma XM, Mueller GP, Mains RE, Eipper BA.

Endocrinology. 2003 Jan;144(1):188-200.


Supplying copper to the cuproenzyme peptidylglycine alpha-amidating monooxygenase.

El Meskini R, Culotta VC, Mains RE, Eipper BA.

J Biol Chem. 2003 Apr 4;278(14):12278-84. Epub 2003 Jan 14.


Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses.

Gaier ED, Rodriguiz RM, Ma XM, Sivaramakrishnan S, Bousquet-Moore D, Wetsel WC, Eipper BA, Mains RE.

J Neurosci. 2010 Oct 13;30(41):13656-69. doi: 10.1523/JNEUROSCI.2200-10.2010.


Lumenal loop M672-P707 of the Menkes protein (ATP7A) transfers copper to peptidylglycine monooxygenase.

Otoikhian A, Barry AN, Mayfield M, Nilges M, Huang Y, Lutsenko S, Blackburn NJ.

J Am Chem Soc. 2012 Jun 27;134(25):10458-68. doi: 10.1021/ja301221s. Epub 2012 Jun 13.


A histidine-rich linker region in peptidylglycine α-amidating monooxygenase has the properties of a pH sensor.

Vishwanatha K, Bäck N, Mains RE, Eipper BA.

J Biol Chem. 2014 May 2;289(18):12404-20. doi: 10.1074/jbc.M113.545947. Epub 2014 Mar 13.


Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction.

Bousquet-Moore D, Prohaska JR, Nillni EA, Czyzyk T, Wetsel WC, Mains RE, Eipper BA.

Neurobiol Dis. 2010 Jan;37(1):130-40. doi: 10.1016/j.nbd.2009.09.016. Epub 2009 Oct 6.


Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper.

Bousquet-Moore D, Ma XM, Nillni EA, Czyzyk TA, Pintar JE, Eipper BA, Mains RE.

Endocrinology. 2009 Apr;150(4):1739-47. doi: 10.1210/en.2008-1202. Epub 2008 Nov 20.


Copper deficiency alters rat peptidylglycine alpha-amidating monooxygenase activity.

Prohaska JR, Bailey WR, Lear PM.

J Nutr. 1995 Jun;125(6):1447-54.


Human macrophage ATP7A is localized in the trans-Golgi apparatus, controls intracellular copper levels, and mediates macrophage responses to dermal wounds.

Kim HW, Chan Q, Afton SE, Caruso JA, Lai B, Weintraub NL, Qin Z.

Inflammation. 2012 Feb;35(1):167-75. doi: 10.1007/s10753-011-9302-z.


Probing the production of amidated peptides following genetic and dietary copper manipulations.

Yin P, Bousquet-Moore D, Annangudi SP, Southey BR, Mains RE, Eipper BA, Sweedler JV.

PLoS One. 2011;6(12):e28679. doi: 10.1371/journal.pone.0028679. Epub 2011 Dec 16.


Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease.

Niciu MJ, Ma XM, El Meskini R, Pachter JS, Mains RE, Eipper BA.

Neurobiol Dis. 2007 Sep;27(3):278-91. Epub 2007 May 23.


Signaling from the secretory granule to the nucleus: Uhmk1 and PAM.

Francone VP, Ifrim MF, Rajagopal C, Leddy CJ, Wang Y, Carson JH, Mains RE, Eipper BA.

Mol Endocrinol. 2010 Aug;24(8):1543-58. doi: 10.1210/me.2009-0381. Epub 2010 Jun 23.

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