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Items: 1 to 20 of 104

1.

Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation.

Purohit A, Rokita AG, Guan X, Chen B, Koval OM, Voigt N, Neef S, Sowa T, Gao Z, Luczak ED, Stefansdottir H, Behunin AC, Li N, El-Accaoui RN, Yang B, Swaminathan PD, Weiss RM, Wehrens XH, Song LS, Dobrev D, Maier LS, Anderson ME.

Circulation. 2013 Oct 15;128(16):1748-57. doi: 10.1161/CIRCULATIONAHA.113.003313. Epub 2013 Sep 12.

2.

Oxidation- and CaMKII-mediated sarcoplasmic reticulum Ca(2+) leak triggers atrial fibrillation in aging.

Guo X, Yuan S, Liu Z, Fang Q.

J Cardiovasc Electrophysiol. 2014 Jun;25(6):645-52. doi: 10.1111/jce.12395. Epub 2014 May 2.

PMID:
24576293
3.

NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII.

Wagner S, Dantz C, Flebbe H, Azizian A, Sag CM, Engels S, Möllencamp J, Dybkova N, Islam T, Shah AM, Maier LS.

J Mol Cell Cardiol. 2014 Oct;75:206-15. doi: 10.1016/j.yjmcc.2014.07.011. Epub 2014 Jul 27.

PMID:
25073061
4.

Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice.

Li N, Wang T, Wang W, Cutler MJ, Wang Q, Voigt N, Rosenbaum DS, Dobrev D, Wehrens XH.

Circ Res. 2012 Feb 3;110(3):465-70. doi: 10.1161/CIRCRESAHA.111.253229. Epub 2011 Dec 8.

5.

Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model.

Li N, Chiang DY, Wang S, Wang Q, Sun L, Voigt N, Respress JL, Ather S, Skapura DG, Jordan VK, Horrigan FT, Schmitz W, Müller FU, Valderrabano M, Nattel S, Dobrev D, Wehrens XH.

Circulation. 2014 Mar 25;129(12):1276-85. doi: 10.1161/CIRCULATIONAHA.113.006611. Epub 2014 Jan 7.

6.

Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.

Chelu MG, Sarma S, Sood S, Wang S, van Oort RJ, Skapura DG, Li N, Santonastasi M, Müller FU, Schmitz W, Schotten U, Anderson ME, Valderrábano M, Dobrev D, Wehrens XH.

J Clin Invest. 2009 Jul;119(7):1940-51.

7.

CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation.

Neef S, Dybkova N, Sossalla S, Ort KR, Fluschnik N, Neumann K, Seipelt R, Schöndube FA, Hasenfuss G, Maier LS.

Circ Res. 2010 Apr 2;106(6):1134-44. doi: 10.1161/CIRCRESAHA.109.203836. Epub 2010 Jan 7.

8.

Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.

He BJ, Joiner ML, Singh MV, Luczak ED, Swaminathan PD, Koval OM, Kutschke W, Allamargot C, Yang J, Guan X, Zimmerman K, Grumbach IM, Weiss RM, Spitz DR, Sigmund CD, Blankesteijn WM, Heymans S, Mohler PJ, Anderson ME.

Nat Med. 2011 Nov 13;17(12):1610-8. doi: 10.1038/nm.2506.

9.

Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signal.

Mesubi OO, Anderson ME.

Cardiovasc Res. 2016 Apr 1;109(4):542-57. doi: 10.1093/cvr/cvw002. Epub 2016 Jan 13. Review.

10.

Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure.

Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS.

Circ Heart Fail. 2009 Nov;2(6):664-75. doi: 10.1161/CIRCHEARTFAILURE.109.865279. Epub 2009 Jul 31.

11.

Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.

Chiang DY, Li N, Wang Q, Alsina KM, Quick AP, Reynolds JO, Wang G, Skapura D, Voigt N, Dobrev D, Wehrens XH.

Cardiovasc Res. 2014 Jul 1;103(1):178-87. doi: 10.1093/cvr/cvu123. Epub 2014 May 8.

12.

Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.

Wagner S, Ruff HM, Weber SL, Bellmann S, Sowa T, Schulte T, Anderson ME, Grandi E, Bers DM, Backs J, Belardinelli L, Maier LS.

Circ Res. 2011 Mar 4;108(5):555-65. doi: 10.1161/CIRCRESAHA.110.221911. Epub 2011 Jan 20.

13.

Oxidized CaMKII causes cardiac sinus node dysfunction in mice.

Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He BJ, Luczak ED, Joiner ML, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, Ogawa M, Chen PS, Efimov I, Dobrev D, Mohler PJ, Hund TJ, Anderson ME.

J Clin Invest. 2011 Aug;121(8):3277-88. doi: 10.1172/JCI57833. Epub 2011 Jul 25.

14.

A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation.

Erickson JR, Joiner ML, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, O'Donnell SE, Aykin-Burns N, Zimmerman MC, Zimmerman K, Ham AJ, Weiss RM, Spitz DR, Shea MA, Colbran RJ, Mohler PJ, Anderson ME.

Cell. 2008 May 2;133(3):462-74. doi: 10.1016/j.cell.2008.02.048.

15.

Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation.

Christ T, Rozmaritsa N, Engel A, Berk E, Knaut M, Metzner K, Canteras M, Ravens U, Kaumann A.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11193-8. doi: 10.1073/pnas.1324132111. Epub 2014 Jul 14. Erratum in: Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):14003.

16.

Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.

Ho HT, Liu B, Snyder JS, Lou Q, Brundage EA, Velez-Cortes F, Wang H, Ziolo MT, Anderson ME, Sen CK, Wehrens XH, Fedorov VV, Biesiadecki BJ, Hund TJ, Györke S.

Cardiovasc Res. 2014 Jan 1;101(1):165-74. doi: 10.1093/cvr/cvt233. Epub 2013 Oct 8.

17.

Triggered firing and atrial fibrillation in transgenic mice with selective atrial fibrosis induced by overexpression of TGF-β1.

Choi EK, Chang PC, Lee YS, Lin SF, Zhu W, Maruyama M, Fishbein MC, Chen Z, Rubart-von der Lohe M, Field LJ, Chen PS.

Circ J. 2012;76(6):1354-62. Epub 2012 Mar 22.

18.

Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker.

Fujita M, Cheng XW, Inden Y, Shimano M, Yoshida N, Inoue A, Yamamoto T, Takeshita K, Kyo S, Taguchi N, Shi GP, Kuzuya M, Okumura K, Murohara T.

J Am Heart Assoc. 2013 Dec 16;2(6):e000503. doi: 10.1161/JAHA.113.000503.

19.

Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling.

Zhou C, Ramaswamy SS, Johnson DE, Vitturi DA, Schopfer FJ, Freeman BA, Hudmon A, Levitan ES.

Sci Rep. 2016 Apr 15;6:23416. doi: 10.1038/srep23416.

20.

Induction of atrial fibrillation by neutrophils critically depends on CD11b/CD18 integrins.

Friedrichs K, Adam M, Remane L, Mollenhauer M, Rudolph V, Rudolph TK, Andrié RP, Stöckigt F, Schrickel JW, Ravekes T, Deuschl F, Nickenig G, Willems S, Baldus S, Klinke A.

PLoS One. 2014 Feb 18;9(2):e89307. doi: 10.1371/journal.pone.0089307. eCollection 2014.

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