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Items: 1 to 20 of 106

1.

TAK1 promotes cell survival by TNFAIP3 and IL-8 dependent and NF-κB independent pathway in HeLa cells exposed to heat stress.

Li P, Furusawa Y, Wei ZL, Sakurai H, Tabuchi Y, Zhao QL, Saiki I, Kondo T.

Int J Hyperthermia. 2013 Nov;29(7):688-95. doi: 10.3109/02656736.2013.828104. Epub 2013 Sep 12.

PMID:
24028082
2.

TGF-β-activated kinase 1 promotes cell cycle arrest and cell survival of X-ray irradiated HeLa cells dependent on p21 induction but independent of NF-κB, p38 MAPK and ERK phosphorylations.

Furusawa Y, Wei ZL, Sakurai H, Tabuchi Y, Li P, Zhao QL, Nomura T, Saiki I, Kondo T.

Radiat Res. 2012 Jun;177(6):766-74. Epub 2012 Apr 10.

PMID:
22490020
3.

Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling.

Qi Z, Shen L, Zhou H, Jiang Y, Lan L, Luo L, Yin Z.

Cell Signal. 2014 Jul;26(7):1616-25. doi: 10.1016/j.cellsig.2014.03.015. Epub 2014 Mar 29.

PMID:
24686082
4.

The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation.

Holtmann H, Enninga J, Kalble S, Thiefes A, Dorrie A, Broemer M, Winzen R, Wilhelm A, Ninomiya-Tsuji J, Matsumoto K, Resch K, Kracht M.

J Biol Chem. 2001 Feb 2;276(5):3508-16. Epub 2000 Oct 24.

5.

Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor beta-activated kinase 1 (TAK1) in interleukin-1beta-induced cell signaling.

Shi L, Zhang Z, Fang S, Xu J, Liu J, Shen J, Fang F, Luo L, Yin Z.

Mol Immunol. 2009 Feb;46(4):541-50. doi: 10.1016/j.molimm.2008.07.019. Epub 2008 Oct 31.

PMID:
18950863
6.

WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway.

Gao D, Wang R, Li B, Yang Y, Zhai Z, Chen DY.

Cell Mol Life Sci. 2009 Aug;66(15):2573-84. doi: 10.1007/s00018-009-0059-6. Epub 2009 Jun 12.

PMID:
19521662
8.

Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation.

Gu M, Ouyang C, Lin W, Zhang T, Cao X, Xia Z, Wang X.

J Immunol. 2014 Mar 15;192(6):2846-56. doi: 10.4049/jimmunol.1302537. Epub 2014 Feb 17. Erratum in: J Immunol. 2015 Aug 1;195(3):1331-2.

9.

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway.

Takaesu G, Surabhi RM, Park KJ, Ninomiya-Tsuji J, Matsumoto K, Gaynor RB.

J Mol Biol. 2003 Feb 7;326(1):105-15.

PMID:
12547194
10.

HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1.

Liu R, Lin Y, Jia R, Geng Y, Liang C, Tan J, Qiao W.

Retrovirology. 2014 Jun 9;11:45. doi: 10.1186/1742-4690-11-45.

11.

Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade.

Choo MK, Kawasaki N, Singhirunnusorn P, Koizumi K, Sato S, Akira S, Saiki I, Sakurai H.

Mol Cancer Ther. 2006 Dec;5(12):2970-6.

13.

Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signaling.

Moon G, Kim J, Min Y, Wi SM, Shim JH, Chun E, Lee KY.

Cell Signal. 2015 Dec;27(12):2524-33. doi: 10.1016/j.cellsig.2015.09.018. Epub 2015 Sep 30.

PMID:
26432169
14.

Role of transforming growth factor-activated kinase-1 on tumor necrosis factor-α actions in human adipose tissue-derived stromal cells.

Lee SY, Lee JH, Shin KK, Kim DS, Kim YS, Bae YC, Jung JS.

Stem Cells Dev. 2015 Apr 1;24(7):836-45. doi: 10.1089/scd.2014.0272. Epub 2014 Dec 31.

PMID:
25350220
15.
16.

The dual-specificity phosphatase DUSP14 negatively regulates tumor necrosis factor- and interleukin-1-induced nuclear factor-κB activation by dephosphorylating the protein kinase TAK1.

Zheng H, Li Q, Chen R, Zhang J, Ran Y, He X, Li S, Shu HB.

J Biol Chem. 2013 Jan 11;288(2):819-25. doi: 10.1074/jbc.M112.412643. Epub 2012 Dec 10.

17.

MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.

Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang SM.

Mol Cancer. 2014 Feb 24;13:35. doi: 10.1186/1476-4598-13-35.

18.

Identification of TGF-β-activated kinase 1 as a possible novel target for renal cell carcinoma intervention.

Meng F, Li Y, Tian X, Fu L, Yin Y, Sui C, Ma P, Jiang Y.

Biochem Biophys Res Commun. 2014 Oct 10;453(1):106-11. doi: 10.1016/j.bbrc.2014.09.070. Epub 2014 Sep 26.

PMID:
25261726
19.

ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction.

Mochida Y, Takeda K, Saitoh M, Nishitoh H, Amagasa T, Ninomiya-Tsuji J, Matsumoto K, Ichijo H.

J Biol Chem. 2000 Oct 20;275(42):32747-52.

20.

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