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Items: 1 to 20 of 147

1.

Tpl2 inhibitors thwart endothelial cell function in angiogenesis and peritoneal dissemination.

Lee WJ, Lan KH, Chou CT, Yi YC, Chen WC, Pan HC, Peng YC, Wang KB, Chen YC, Chao TH, Tien HR, Sheu WH, Sheu ML.

Neoplasia. 2013 Sep;15(9):1036-48.

2.

Honokiol thwarts gastric tumor growth and peritoneal dissemination by inhibiting Tpl2 in an orthotopic model.

Pan HC, Lai DW, Lan KH, Shen CC, Wu SM, Chiu CS, Wang KB, Sheu ML.

Carcinogenesis. 2013 Nov;34(11):2568-79. doi: 10.1093/carcin/bgt243. Epub 2013 Jul 4.

PMID:
23828905
3.

Tpl2 is a key mediator of arsenite-induced signal transduction.

Lee KM, Lee KW, Bode AM, Lee HJ, Dong Z.

Cancer Res. 2009 Oct 15;69(20):8043-9. doi: 10.1158/0008-5472.CAN-09-2316. Epub 2009 Oct 6.

4.

Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.

Huang SW, Lien JC, Kuo SC, Huang TF.

Carcinogenesis. 2012 May;33(5):1022-30. doi: 10.1093/carcin/bgs127. Epub 2012 Mar 20.

PMID:
22436611
5.

Transforming growth factor-β-activated kinase 1 regulates angiogenesis via AMP-activated protein kinase-α1 and redox balance in endothelial cells.

Zippel N, Malik RA, Frömel T, Popp R, Bess E, Strilic B, Wettschureck N, Fleming I, Fisslthaler B.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2792-9. doi: 10.1161/ATVBAHA.113.301848. Epub 2013 Sep 26.

6.

A novel inhibitor of c-Met and VEGF receptor tyrosine kinases with a broad spectrum of in vivo antitumor activities.

Awazu Y, Nakamura K, Mizutani A, Kakoi Y, Iwata H, Yamasaki S, Miyamoto N, Imamura S, Miki H, Hori A.

Mol Cancer Ther. 2013 Jun;12(6):913-24. doi: 10.1158/1535-7163.MCT-12-1011. Epub 2013 Apr 2.

7.

The antitumor effect of a novel angiogenesis inhibitor (an octahydronaphthalene derivative) targeting both VEGF receptor and NF-κB pathway.

Watari K, Nakamura M, Fukunaga Y, Furuno A, Shibata T, Kawahara A, Hosoi F, Kuwano T, Kuwano M, Ono M.

Int J Cancer. 2012 Jul 15;131(2):310-21. doi: 10.1002/ijc.26356. Epub 2011 Sep 14.

8.

A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology.

Tate CM, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, Ricci-Vitiani L, D'Alessandris QG, Morgante L, Giannetti S, Larocca LM, Todaro M, Benfante A, Colorito ML, Stassi G, De Maria R, Rowlinson S, Stancato L.

PLoS One. 2015 Apr 28;10(4):e0125697. doi: 10.1371/journal.pone.0125697. eCollection 2015.

9.

miR-342-5p Is a Notch Downstream Molecule and Regulates Multiple Angiogenic Pathways Including Notch, Vascular Endothelial Growth Factor and Transforming Growth Factor β Signaling.

Yan XC, Cao J, Liang L, Wang L, Gao F, Yang ZY, Duan JL, Chang TF, Deng SM, Liu Y, Dou GR, Zhang J, Zheng QJ, Zhang P, Han H.

J Am Heart Assoc. 2016 Feb 8;5(2). pii: e003042. doi: 10.1161/JAHA.115.003042.

10.

Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity.

Kim G, Khanal P, Lim SC, Yun HJ, Ahn SG, Ki SH, Choi HS.

Carcinogenesis. 2013 Feb;34(2):341-50. doi: 10.1093/carcin/bgs342. Epub 2012 Nov 3.

PMID:
23125217
11.

Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect.

Tan WF, Zhang XW, Li MH, Yue JM, Chen Y, Lin LP, Ding J.

Eur J Pharmacol. 2004 Sep 24;499(3):219-28.

PMID:
15381043
13.

KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer.

Hong SW, Jung KH, Park BH, Zheng HM, Lee HS, Choi MJ, Yun JI, Kang NS, Lee J, Hong SS.

Cancer Lett. 2013 May 10;332(1):74-82. doi: 10.1016/j.canlet.2013.01.015. Epub 2013 Jan 21.

PMID:
23348694
14.

Isogambogenic acid inhibits tumour angiogenesis by suppressing Rho GTPases and vascular endothelial growth factor receptor 2 signalling pathway.

Fan Y, Peng A, He S, Shao X, Nie C, Chen L.

J Chemother. 2013 Oct;25(5):298-308. doi: 10.1179/1973947813Y.0000000079.

PMID:
24070138
15.

Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice.

Liu SH, Wang KB, Lan KH, Lee WJ, Pan HC, Wu SM, Peng YC, Chen YC, Shen CC, Cheng HC, Liao KK, Sheu ML.

PLoS One. 2012;7(8):e43711. doi: 10.1371/journal.pone.0043711. Epub 2012 Aug 24.

16.

Paris Saponin II suppresses the growth of human ovarian cancer xenografts via modulating VEGF-mediated angiogenesis and tumor cell migration.

Xiao X, Yang M, Xiao J, Zou J, Huang Q, Yang K, Zhang B, Yang F, Liu S, Wang H, Bai P.

Cancer Chemother Pharmacol. 2014 Apr;73(4):807-18. doi: 10.1007/s00280-014-2408-x. Epub 2014 Mar 18.

PMID:
24638862
17.

Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis.

Pang X, Yi Z, Zhang X, Sung B, Qu W, Lian X, Aggarwal BB, Liu M.

Cancer Res. 2009 Jul 15;69(14):5893-900. doi: 10.1158/0008-5472.CAN-09-0755. Epub 2009 Jun 30.

18.

Antiangiogenic Activity of Acer tegmentosum Maxim Water Extract in Vitro and in Vivo.

Kim EC, Kim SH, Piao SJ, Kim TJ, Bae K, Kim HS, Hong SS, Lee BI, Nam M.

J Korean Med Sci. 2015 Jul;30(7):979-87. doi: 10.3346/jkms.2015.30.7.979. Epub 2015 Jun 10.

19.

TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells.

Kim YM, Kim YM, Lee YM, Kim HS, Kim JD, Choi Y, Kim KW, Lee SY, Kwon YG.

J Biol Chem. 2002 Mar 1;277(9):6799-805. Epub 2001 Dec 10.

20.

Mitogen-activated protein 3 kinase 6 mediates angiogenic and tumorigenic effects via vascular endothelial growth factor expression.

Eto N, Miyagishi M, Inagi R, Fujita T, Nangaku M.

Am J Pathol. 2009 Apr;174(4):1553-63. doi: 10.2353/ajpath.2009.080190. Epub 2009 Feb 26.

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