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Items: 1 to 20 of 107

1.

The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion.

Fénelon K, Xu B, Lai CS, Mukai J, Markx S, Stark KL, Hsu PK, Gan WB, Fischbach GD, MacDermott AB, Karayiorgou M, Gogos JA.

J Neurosci. 2013 Sep 11;33(37):14825-39. doi: 10.1523/JNEUROSCI.1611-13.2013.

2.

Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex.

Fénelon K, Mukai J, Xu B, Hsu PK, Drew LJ, Karayiorgou M, Fischbach GD, Macdermott AB, Gogos JA.

Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4447-52. doi: 10.1073/pnas.1101219108. Epub 2011 Feb 28.

3.

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.

Crabtree GW, Sun Z, Kvajo M, Broek JA, Fénelon K, McKellar H, Xiao L, Xu B, Bahn S, O'Donnell JM, Gogos JA.

J Neurosci. 2017 Apr 12;37(15):4158-4180. doi: 10.1523/JNEUROSCI.4345-15.2017. Epub 2017 Mar 10.

PMID:
28283561
4.

Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.

Carlisle HJ, Luong TN, Medina-Marino A, Schenker L, Khorosheva E, Indersmitten T, Gunapala KM, Steele AD, O'Dell TJ, Patterson PH, Kennedy MB.

J Neurosci. 2011 Nov 9;31(45):16194-207. doi: 10.1523/JNEUROSCI.5877-10.2011.

5.

Age-dependent microRNA control of synaptic plasticity in 22q11 deletion syndrome and schizophrenia.

Earls LR, Fricke RG, Yu J, Berry RB, Baldwin LT, Zakharenko SS.

J Neurosci. 2012 Oct 10;32(41):14132-44. doi: 10.1523/JNEUROSCI.1312-12.2012.

6.

Dysregulation of synaptic proteins, dendritic spine abnormalities and pathological plasticity of synapses as experience-dependent mediators of cognitive and psychiatric symptoms in Huntington's disease.

Nithianantharajah J, Hannan AJ.

Neuroscience. 2013 Oct 22;251:66-74. doi: 10.1016/j.neuroscience.2012.05.043. Epub 2012 May 24. Review.

PMID:
22633949
7.

Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.

Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K.

J Neurosci. 2011 Jan 5;31(1):346-58. doi: 10.1523/JNEUROSCI.4816-10.2011.

8.

PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 Activity.

Mayanagi T, Yasuda H, Sobue K.

J Neurosci. 2015 Oct 21;35(42):14327-40. doi: 10.1523/JNEUROSCI.2349-15.2015.

9.

Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology.

Bongmba OY, Martinez LA, Elhardt ME, Butler K, Tejada-Simon MV.

Brain Res. 2011 Jul 5;1399:79-95. doi: 10.1016/j.brainres.2011.05.020. Epub 2011 May 17. Erratum in: Brain Res. 2011 Nov 14;1423:114-5.

10.

Dendritic spine instability leads to progressive neocortical spine loss in a mouse model of Huntington's disease.

Murmu RP, Li W, Holtmaat A, Li JY.

J Neurosci. 2013 Aug 7;33(32):12997-3009. doi: 10.1523/JNEUROSCI.5284-12.2013.

11.

Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.

Thomazeau A, Lassalle O, Iafrati J, Souchet B, Guedj F, Janel N, Chavis P, Delabar J, Manzoni OJ.

J Neurosci. 2014 Jan 22;34(4):1138-47. doi: 10.1523/JNEUROSCI.2852-13.2014.

12.

SIRT1 is essential for normal cognitive function and synaptic plasticity.

Michán S, Li Y, Chou MM, Parrella E, Ge H, Long JM, Allard JS, Lewis K, Miller M, Xu W, Mervis RF, Chen J, Guerin KI, Smith LE, McBurney MW, Sinclair DA, Baudry M, de Cabo R, Longo VD.

J Neurosci. 2010 Jul 21;30(29):9695-707. doi: 10.1523/JNEUROSCI.0027-10.2010.

13.

The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory.

Vogel-Ciernia A, Matheos DP, Barrett RM, Kramár EA, Azzawi S, Chen Y, Magnan CN, Zeller M, Sylvain A, Haettig J, Jia Y, Tran A, Dang R, Post RJ, Chabrier M, Babayan AH, Wu JI, Crabtree GR, Baldi P, Baram TZ, Lynch G, Wood MA.

Nat Neurosci. 2013 May;16(5):552-61. doi: 10.1038/nn.3359. Epub 2013 Mar 24.

14.

Impaired synaptic plasticity in the prefrontal cortex of mice with developmentally decreased number of interneurons.

Konstantoudaki X, Chalkiadaki K, Tivodar S, Karagogeos D, Sidiropoulou K.

Neuroscience. 2016 May 13;322:333-45. doi: 10.1016/j.neuroscience.2016.02.048. Epub 2016 Feb 27.

PMID:
26926965
15.

A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition.

Kvajo M, McKellar H, Arguello PA, Drew LJ, Moore H, MacDermott AB, Karayiorgou M, Gogos JA.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):7076-81. doi: 10.1073/pnas.0802615105. Epub 2008 May 5.

16.

Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice.

Pan B, Wang W, Zhong P, Blankman JL, Cravatt BF, Liu QS.

J Neurosci. 2011 Sep 21;31(38):13420-30. doi: 10.1523/JNEUROSCI.2075-11.2011.

17.

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex.

Schofield CM, Hsu R, Barker AJ, Gertz CC, Blelloch R, Ullian EM.

Neural Dev. 2011 Apr 5;6:11. doi: 10.1186/1749-8104-6-11.

18.

Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia.

Mukai J, Tamura M, Fénelon K, Rosen AM, Spellman TJ, Kang R, MacDermott AB, Karayiorgou M, Gordon JA, Gogos JA.

Neuron. 2015 May 6;86(3):680-95. doi: 10.1016/j.neuron.2015.04.003. Epub 2015 Apr 23.

19.

Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment.

Dumitriu D, Hao J, Hara Y, Kaufmann J, Janssen WG, Lou W, Rapp PR, Morrison JH.

J Neurosci. 2010 Jun 2;30(22):7507-15. doi: 10.1523/JNEUROSCI.6410-09.2010.

20.

Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome.

Piskorowski RA, Nasrallah K, Diamantopoulou A, Mukai J, Hassan SI, Siegelbaum SA, Gogos JA, Chevaleyre V.

Neuron. 2016 Jan 6;89(1):163-76. doi: 10.1016/j.neuron.2015.11.036.

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