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Items: 1 to 20 of 106

1.

A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout.

Sakiyama M, Matsuo H, Shimizu S, Nakashima H, Nakayama A, Chiba T, Naito M, Takada T, Suzuki H, Hamajima N, Ichida K, Shimizu T, Shinomiya N.

Drug Metab Pharmacokinet. 2014;29(2):208-10. Epub 2013 Sep 10.

2.

Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects.

Flynn TJ, Phipps-Green A, Hollis-Moffatt JE, Merriman ME, Topless R, Montgomery G, Chapman B, Stamp LK, Dalbeth N, Merriman TR.

Arthritis Res Ther. 2013;15(6):R220.

3.

NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout.

Chiba T, Matsuo H, Kawamura Y, Nagamori S, Nishiyama T, Wei L, Nakayama A, Nakamura T, Sakiyama M, Takada T, Taketani Y, Suma S, Naito M, Oda T, Kumagai H, Moriyama Y, Ichida K, Shimizu T, Kanai Y, Shinomiya N.

Arthritis Rheumatol. 2015 Jan;67(1):281-7. doi: 10.1002/art.38884.

4.

Common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility.

Nakayama A, Matsuo H, Shimizu T, Ogata H, Takada Y, Nakashima H, Nakamura T, Shimizu S, Chiba T, Sakiyama M, Ushiyama C, Takada T, Inoue K, Kawai S, Hishida A, Wakai K, Hamajima N, Ichida K, Sakurai Y, Kato Y, Shimizu T, Shinomiya N.

Hum Cell. 2013 Dec;26(4):133-6. doi: 10.1007/s13577-013-0073-8. Epub 2013 Aug 29.

5.

Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate.

Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Wempe MF, Endou H, Sakurai H.

J Biol Chem. 2010 Nov 5;285(45):35123-32. doi: 10.1074/jbc.M110.121301. Epub 2010 Sep 1.

6.

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.

Matsuo H, Yamamoto K, Nakaoka H, Nakayama A, Sakiyama M, Chiba T, Takahashi A, Nakamura T, Nakashima H, Takada Y, Danjoh I, Shimizu S, Abe J, Kawamura Y, Terashige S, Ogata H, Tatsukawa S, Yin G, Okada R, Morita E, Naito M, Tokumasu A, Onoue H, Iwaya K, Ito T, Takada T, Inoue K, Kato Y, Nakamura Y, Sakurai Y, Suzuki H, Kanai Y, Hosoya T, Hamajima N, Inoue I, Kubo M, Ichida K, Ooyama H, Shimizu T, Shinomiya N.

Ann Rheum Dis. 2016 Apr;75(4):652-9. doi: 10.1136/annrheumdis-2014-206191. Epub 2015 Feb 2.

7.

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.

Nakayama A, Nakaoka H, Yamamoto K, Sakiyama M, Shaukat A, Toyoda Y, Okada Y, Kamatani Y, Nakamura T, Takada T, Inoue K, Yasujima T, Yuasa H, Shirahama Y, Nakashima H, Shimizu S, Higashino T, Kawamura Y, Ogata H, Kawaguchi M, Ohkawa Y, Danjoh I, Tokumasu A, Ooyama K, Ito T, Kondo T, Wakai K, Stiburkova B, Pavelka K, Stamp LK, Dalbeth N; Eurogout Consortium, Sakurai Y, Suzuki H, Hosoyamada M, Fujimori S, Yokoo T, Hosoya T, Inoue I, Takahashi A, Kubo M, Ooyama H, Shimizu T, Ichida K, Shinomiya N, Merriman TR, Matsuo H; Eurogout Consortium.

Ann Rheum Dis. 2017 May;76(5):869-877. doi: 10.1136/annrheumdis-2016-209632. Epub 2016 Nov 29.

8.

The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people.

Yamagishi K, Tanigawa T, Kitamura A, Köttgen A, Folsom AR, Iso H; CIRCS Investigators.

Rheumatology (Oxford). 2010 Aug;49(8):1461-5. doi: 10.1093/rheumatology/keq096. Epub 2010 Apr 25.

PMID:
20421215
9.

Tubular urate transporter gene polymorphisms differentiate patients with gout who have normal and decreased urinary uric acid excretion.

Torres RJ, de Miguel E, Bailén R, Banegas JR, Puig JG.

J Rheumatol. 2014 Sep;41(9):1863-70. doi: 10.3899/jrheum.140126. Epub 2014 Aug 15.

PMID:
25128519
10.

A urate gene-by-diuretic interaction and gout risk in participants with hypertension: results from the ARIC study.

McAdams-DeMarco MA, Maynard JW, Baer AN, Kao LW, Kottgen A, Coresh J.

Ann Rheum Dis. 2013 May;72(5):701-6. doi: 10.1136/annrheumdis-2011-201186. Epub 2012 Jun 29.

11.

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.

Woodward OM, Köttgen A, Coresh J, Boerwinkle E, Guggino WB, Köttgen M.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10338-42. doi: 10.1073/pnas.0901249106. Epub 2009 Jun 8.

12.

Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.

Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Noshiro R, Takeda M, Kanai Y, Sophasan S, Endou H.

J Pharmacol Sci. 2004 Mar;94(3):297-304.

13.

Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men.

Tanner C, Boocock J, Stahl EA, Dobbyn A, Mandal AK, Cadzow M, Phipps-Green AJ, Topless RK, Hindmarsh JH, Stamp LK, Dalbeth N, Choi HK, Mount DB, Merriman TR.

Arthritis Rheumatol. 2017 Jul;69(7):1461-1469. doi: 10.1002/art.40110. Epub 2017 May 31.

PMID:
28371506
14.

Control of renal uric acid excretion and gout.

Taniguchi A, Kamatani N.

Curr Opin Rheumatol. 2008 Mar;20(2):192-7. doi: 10.1097/BOR.0b013e3282f33f87. Review.

PMID:
18349750
15.

The hURAT1 rs559946 polymorphism and the incidence of gout in Han Chinese men.

Li C, Yu Q, Han L, Wang C, Chu N, Liu S.

Scand J Rheumatol. 2014;43(1):35-42. doi: 10.3109/03009742.2013.808375. Epub 2013 Aug 28.

PMID:
23981340
16.

Association between intronic SNP in urate-anion exchanger gene, SLC22A12, and serum uric acid levels in Japanese.

Shima Y, Teruya K, Ohta H.

Life Sci. 2006 Nov 2;79(23):2234-7. Epub 2006 Aug 1.

PMID:
16920156
17.

Genetic variants of human organic anion transporter 4 demonstrate altered transport of endogenous substrates.

Shima JE, Komori T, Taylor TR, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Ferrin TE, Giacomini KM.

Am J Physiol Renal Physiol. 2010 Oct;299(4):F767-75. doi: 10.1152/ajprenal.00312.2010. Epub 2010 Jul 28.

18.

Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout.

Fatima T, Altaf S, Phipps-Green A, Topless R, Flynn TJ, Stamp LK, Dalbeth N, Merriman TR.

Rheumatol Int. 2016 Feb;36(2):255-61. doi: 10.1007/s00296-015-3370-6. Epub 2015 Sep 26.

20.

Role of the urate transporter SLC2A9 gene in susceptibility to gout in New Zealand Māori, Pacific Island, and Caucasian case-control sample sets.

Hollis-Moffatt JE, Xu X, Dalbeth N, Merriman ME, Topless R, Waddell C, Gow PJ, Harrison AA, Highton J, Jones PB, Stamp LK, Merriman TR.

Arthritis Rheum. 2009 Nov;60(11):3485-92. doi: 10.1002/art.24938.

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