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Items: 1 to 20 of 142

1.

Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin.

Xia YL, Liang SC, Zhu LL, Ge GB, He GY, Ning J, Lv X, Ma XC, Yang L, Yang SL.

Drug Metab Pharmacokinet. 2014;29(2):135-40. Epub 2013 Sep 10.

2.

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in-vitro glucuronidation of arctigenin.

Xin H, Xia YL, Hou J, Wang P, He W, Yang L, Ge GB, Xu W.

J Pharm Pharmacol. 2015 Dec;67(12):1673-81. doi: 10.1111/jphp.12483. Epub 2015 Sep 26.

PMID:
26407805
3.

Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.

Shiraga T, Yajima K, Suzuki K, Suzuki K, Hashimoto T, Iwatsubo T, Miyashita A, Usui T.

Drug Metab Dispos. 2012 Feb;40(2):276-82. doi: 10.1124/dmd.111.042614. Epub 2011 Oct 26.

4.
5.

Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.

Ma L, Sun J, Peng Y, Zhang R, Shao F, Hu X, Zhu J, Wang X, Cheng X, Zhu Y, Wan P, Feng D, Wu H, Wang G.

Drug Metab Dispos. 2012 Apr;40(4):734-41. doi: 10.1124/dmd.111.043356. Epub 2012 Jan 11.

6.

Characterization of N-glucuronidation of 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051): a new xanthine oxidoreductase inhibitor.

Omura K, Nakazawa T, Sato T, Iwanaga T, Nagata O.

Drug Metab Dispos. 2007 Dec;35(12):2143-8. Epub 2007 Aug 30.

7.

Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.

Kerdpin O, Elliot DJ, Mackenzie PI, Miners JO.

Drug Metab Dispos. 2006 Dec;34(12):1950-3. Epub 2006 Sep 19.

8.

Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the C-glucuronidation of phenylbutazone.

Nishiyama T, Kobori T, Arai K, Ogura K, Ohnuma T, Ishii K, Hayashi K, Hiratsuka A.

Arch Biochem Biophys. 2006 Oct 1;454(1):72-9. Epub 2006 Aug 7.

PMID:
16949544
9.

Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases.

Ruan JQ, Yan R.

Chem Biol Interact. 2014 Sep 5;220:231-40. doi: 10.1016/j.cbi.2014.07.003. Epub 2014 Jul 18.

PMID:
25044472
10.

Identification of UDP-glucuronosyltransferase isoforms responsible for leonurine glucuronidation in human liver and intestinal microsomes.

Tan B, Cai W, Zhang J, Zhou N, Ma G, Yang P, Zhu Q, Zhu Y.

Xenobiotica. 2014 Sep;44(9):775-84. doi: 10.3109/00498254.2014.898808. Epub 2014 Mar 17.

PMID:
24635759
11.

UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for puerarin metabolism in human liver microsomes.

Luo CF, Cai B, Hou N, Yuan M, Liu SM, Ji H, Xiong LG, Xiong W, Luo JD, Chen MS.

Arch Toxicol. 2012 Nov;86(11):1681-90. doi: 10.1007/s00204-012-0874-7. Epub 2012 May 31. Erratum in: Arch Toxicol. 2012 Nov;86(11):1691.

PMID:
22648071
12.
13.

Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.

Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.

Drug Metab Dispos. 2005 Jan;33(1):23-30. Epub 2004 Oct 6.

14.

Regio- and isoform-specific glucuronidation of psoralidin: evaluation of 3-o-glucuronidation as a functional marker for UGT1A9.

Sun H, Ma Z, Lu D, Wu B.

J Pharm Sci. 2015 Jul;104(7):2369-77. doi: 10.1002/jps.24464. Epub 2015 May 4.

PMID:
25941108
15.

Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.

Li T, Zheng Y, Fu F, Ji H, Chen X, Zhao Y, Zhao D, Li N, Zhang L.

Xenobiotica. 2011 Jul;41(7):530-7. doi: 10.3109/00498254.2011.573018. Epub 2011 Apr 27.

PMID:
21524190
16.

Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.

Chen M, LeDuc B, Kerr S, Howe D, Williams DA.

Drug Metab Dispos. 2010 Mar;38(3):368-75. doi: 10.1124/dmd.109.029900. Epub 2009 Dec 11.

17.

UDP-glucuronosyltransferase 1A6 is the major isozyme responsible for protocatechuic aldehyde glucuronidation in human liver microsomes.

Liu HX, Liu Y, Zhang JW, Li W, Liu HT, Yang L.

Drug Metab Dispos. 2008 Aug;36(8):1562-9. doi: 10.1124/dmd.108.020560. Epub 2008 May 12.

18.

Characterization of hepatic and intestinal glucuronidation of magnolol: application of the relative activity factor approach to decipher the contributions of multiple UDP-glucuronosyltransferase isoforms.

Zhu L, Ge G, Zhang H, Liu H, He G, Liang S, Zhang Y, Fang Z, Dong P, Finel M, Yang L.

Drug Metab Dispos. 2012 Mar;40(3):529-38. doi: 10.1124/dmd.111.042192. Epub 2011 Dec 16.

19.

In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.

Tong Z, Li H, Goljer I, McConnell O, Chandrasekaran A.

Drug Metab Dispos. 2007 Dec;35(12):2203-10. Epub 2007 Sep 17.

20.

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