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Items: 1 to 20 of 88

1.

Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells.

Tanios R, Bekdash A, Kassab E, Stone E, Georgiou G, Frankel AE, Abi-Habib RJ.

Leuk Res. 2013 Nov;37(11):1565-71. doi: 10.1016/j.leukres.2013.08.007. Epub 2013 Aug 16.

PMID:
24018014
2.

Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells.

Khoury O, Ghazale N, Stone E, El-Sibai M, Frankel AE, Abi-Habib RJ.

J Neurooncol. 2015 Mar;122(1):75-85. doi: 10.1007/s11060-014-1698-5. Epub 2015 Jan 8.

PMID:
25567351
3.

Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells.

Agrawal V, Woo JH, Mauldin JP, Jo C, Stone EM, Georgiou G, Frankel AE.

Anticancer Drugs. 2012 Jan;23(1):51-64. doi: 10.1097/CAD.0b013e32834ae42b.

PMID:
21955999
4.
5.

Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.

Mussai F, Egan S, Higginbotham-Jones J, Perry T, Beggs A, Odintsova E, Loke J, Pratt G, U KP, Lo A, Ng M, Kearns P, Cheng P, De Santo C.

Blood. 2015 Apr 9;125(15):2386-96. doi: 10.1182/blood-2014-09-600643. Epub 2015 Feb 20.

6.

Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells.

Tawil M, Bekdash A, Mroueh M, Daher CF, Abi-Habib RJ.

Asian Pac J Cancer Prev. 2015;16(2):761-7.

7.

Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms.

Martelli AM, Papa V, Tazzari PL, Ricci F, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Martinelli G, Ottaviani E, Pagliaro P, Horn S, Bäsecke J, Lindner LH, Eibl H, McCubrey JA.

Leukemia. 2010 Apr;24(4):687-98. doi: 10.1038/leu.2010.32. Epub 2010 Mar 4.

PMID:
20200557
8.

Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.

Lam TL, Wong GK, Chong HC, Cheng PN, Choi SC, Chow TL, Kwok SY, Poon RT, Wheatley DN, Lo WH, Leung YC.

Cancer Lett. 2009 May 8;277(1):91-100. doi: 10.1016/j.canlet.2008.11.031. Epub 2009 Jan 12.

PMID:
19138817
9.

Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo.

Miraki-Moud F, Ghazaly E, Ariza-McNaughton L, Hodby KA, Clear A, Anjos-Afonso F, Liapis K, Grantham M, Sohrabi F, Cavenagh J, Bomalaski JS, Gribben JG, Szlosarek PW, Bonnet D, Taussig DC.

Blood. 2015 Jun 25;125(26):4060-8. doi: 10.1182/blood-2014-10-608133. Epub 2015 Apr 20.

10.

Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis.

Delage B, Luong P, Maharaj L, O'Riain C, Syed N, Crook T, Hatzimichael E, Papoudou-Bai A, Mitchell TJ, Whittaker SJ, Cerio R, Gribben J, Lemoine N, Bomalaski J, Li CF, Joel S, Fitzgibbon J, Chen LT, Szlosarek PW.

Cell Death Dis. 2012 Jul 5;3:e342. doi: 10.1038/cddis.2012.83.

11.
12.

Citrulline can preserve proliferation and prevent the loss of CD3 zeta chain under conditions of low arginine.

Bansal V, Rodriguez P, Wu G, Eichler DC, Zabaleta J, Taheri F, Ochoa JB.

JPEN J Parenter Enteral Nutr. 2004 Nov-Dec;28(6):423-30.

PMID:
15568289
13.

Deprivation of arginine by recombinant human arginase in prostate cancer cells.

Hsueh EC, Knebel SM, Lo WH, Leung YC, Cheng PN, Hsueh CT.

J Hematol Oncol. 2012 Apr 30;5:17. doi: 10.1186/1756-8722-5-17.

14.

Bioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.

Glazer ES, Kaluarachchi WD, Massey KL, Zhu C, Curley SA.

Surgery. 2010 Aug;148(2):310-8. doi: 10.1016/j.surg.2010.03.022. Epub 2010 May 13.

15.

Recombinant human arginase toxicity in mice is reduced by citrulline supplementation.

Mauldin JP, Zeinali I, Kleypas K, Woo JH, Blackwood RS, Jo CH, Stone EM, Georgiou G, Frankel AE.

Transl Oncol. 2012 Feb;5(1):26-31. Epub 2012 Feb 1.

16.

Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells.

Wang Z, Shi X, Li Y, Zeng X, Fan J, Sun Y, Xian Z, Zhang G, Wang S, Hu H, Ju D.

Appl Microbiol Biotechnol. 2014 Mar;98(6):2485-94. doi: 10.1007/s00253-013-5118-0. Epub 2013 Aug 6.

PMID:
23917632
17.

Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma.

Tate DJ Jr, Vonderhaar DJ, Caldas YA, Metoyer T, Patterson JR 4th, Aviles DH, Zea AH.

J Hematol Oncol. 2008 Sep 25;1:14. doi: 10.1186/1756-8722-1-14.

18.

L-arginine uptake, the citrulline-NO cycle and arginase II in the rat brain: an in situ hybridization study.

Braissant O, Gotoh T, Loup M, Mori M, Bachmann C.

Brain Res Mol Brain Res. 1999 Jul 5;70(2):231-41.

PMID:
10407171
19.

Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.

Li Y, Zeng X, Wang S, Fan J, Wang Z, Song P, Mei X, Ju D.

Tumour Biol. 2016 May;37(5):6627-35. doi: 10.1007/s13277-015-4253-x. Epub 2015 Dec 7.

PMID:
26643895

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