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Items: 1 to 20 of 112

1.

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling.

Zhang J, Cao H, Zhang B, Cao H, Xu X, Ruan H, Yi T, Tan L, Qu R, Song G, Wang B, Hu T.

J Cell Mol Med. 2013 Nov;17(11):1484-93. doi: 10.1111/jcmm.12119. Epub 2013 Sep 9.

3.

Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signaling.

Lang M, Borgmann M, Oberhuber G, Evstatiev R, Jimenez K, Dammann KW, Jambrich M, Khare V, Campregher C, Ristl R, Gasche C.

Mol Cancer. 2013 May 13;12(1):41. doi: 10.1186/1476-4598-12-41.

4.

A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.

Zeineldin M, Cunningham J, McGuinness W, Alltizer P, Cowley B, Blanchat B, Xu W, Pinson D, Neufeld KL.

Oncogene. 2012 May 10;31(19):2423-37. doi: 10.1038/onc.2011.434. Epub 2011 Sep 26.

5.

Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer.

Kumar A, Pandurangan AK, Lu F, Fyrst H, Zhang M, Byun HS, Bittman R, Saba JD.

Carcinogenesis. 2012 Sep;33(9):1726-35. doi: 10.1093/carcin/bgs174. Epub 2012 May 11.

6.

Rapamycin inhibition of polyposis and progression to dysplasia in a mouse model.

Hardiman KM, Liu J, Feng Y, Greenson JK, Fearon ER.

PLoS One. 2014 Apr 24;9(4):e96023. doi: 10.1371/journal.pone.0096023. eCollection 2014.

7.

Berberine inhibits the proliferation of colon cancer cells by inactivating Wnt/β-catenin signaling.

Wu K, Yang Q, Mu Y, Zhou L, Liu Y, Zhou Q, He B.

Int J Oncol. 2012 Jul;41(1):292-8. doi: 10.3892/ijo.2012.1423. Epub 2012 Apr 2.

PMID:
22469784
8.

Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signalling.

Brauburger K, Akyildiz S, Ruppert JG, Graeb M, Bernkopf DB, Hadjihannas MV, Behrens J.

FEBS J. 2014 Feb;281(3):787-801. doi: 10.1111/febs.12624. Epub 2013 Dec 12.

9.

Chemoprevention of intestinal adenomatous polyposis by acetyl-11-keto-beta-boswellic acid in APC(Min/+) mice.

Liu HP, Gao ZH, Cui SX, Wang Y, Li BY, Lou HX, Qu XJ.

Int J Cancer. 2013 Jun 1;132(11):2667-81. doi: 10.1002/ijc.27929. Epub 2012 Nov 26.

10.

Protein kinase C delta negatively modulates canonical Wnt pathway and cell proliferation in colon tumor cell lines.

Hernández-Maqueda JG, Luna-Ulloa LB, Santoyo-Ramos P, Castañeda-Patlán MC, Robles-Flores M.

PLoS One. 2013;8(3):e58540. doi: 10.1371/journal.pone.0058540. Epub 2013 Mar 8.

11.

Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.

Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ.

PLoS One. 2014 Jul 8;9(7):e101969. doi: 10.1371/journal.pone.0101969. eCollection 2014.

12.

Chemopreventive effects of berberine on intestinal tumor development in Apcmin/+ mice.

Cao H, Song S, Zhang H, Zhang Y, Qu R, Yang B, Jing Y, Hu T, Yan F, Wang B.

BMC Gastroenterol. 2013 Nov 27;13:163. doi: 10.1186/1471-230X-13-163.

13.

Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis.

Hu PJ, Knoepp SM, Wu R, Cho KR.

Genes Chromosomes Cancer. 2012 Mar;51(3):283-9. doi: 10.1002/gcc.20953. Epub 2011 Nov 25.

14.

Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC.

Preet R, Mohapatra P, Das D, Satapathy SR, Choudhuri T, Wyatt MD, Kundu CN.

Carcinogenesis. 2013 Feb;34(2):277-86. doi: 10.1093/carcin/bgs351. Epub 2012 Nov 5.

PMID:
23129580
15.

Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin.

Freeman TJ, Smith JJ, Chen X, Washington MK, Roland JT, Means AL, Eschrich SA, Yeatman TJ, Deane NG, Beauchamp RD.

Gastroenterology. 2012 Mar;142(3):562-571.e2. doi: 10.1053/j.gastro.2011.11.026. Epub 2011 Nov 22.

16.

The Wnt/β-catenin/T-cell factor 4 pathway up-regulates high-mobility group A1 expression in colon cancer.

Bush BM, Brock AT, Deng JA, Nelson RA, Sumter TF.

Cell Biochem Funct. 2013 Apr;31(3):228-36. doi: 10.1002/cbf.2876. Epub 2012 Sep 7.

17.

Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.

Li S, Ghaleb AM, He J, Bughani U, Bialkowska AB, Yang VW, Joshi HC.

Int J Cancer. 2012 Sep 15;131(6):1435-44. doi: 10.1002/ijc.27344. Epub 2012 Feb 9.

18.

Inhibition of intestinal adenoma formation in APC(Min/+) mice by Riccardin D, a natural product derived from liverwort plant Dumortiera hirsuta.

Liu HP, Gao ZH, Cui SX, Sun DF, Wang Y, Zhao CR, Lou HX, Qu XJ.

PLoS One. 2012;7(3):e33243. doi: 10.1371/journal.pone.0033243. Epub 2012 Mar 14.

19.

Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression.

Yekkala K, Baudino TA.

Mol Cancer Res. 2007 Dec;5(12):1296-303. doi: 10.1158/1541-7786.MCR-07-0232. Erratum in: Mol Cancer Res. 2008 Feb;6(2):340.

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