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Items: 1 to 20 of 187

1.

Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation.

Shajib MS, Wang H, Kim JJ, Sunjic I, Ghia JE, Denou E, Collins M, Denburg JA, Khan WI.

PLoS One. 2013 Aug 28;8(8):e72774. doi: 10.1371/journal.pone.0072774. eCollection 2013.

2.

Serotonin has a key role in pathogenesis of experimental colitis.

Ghia JE, Li N, Wang H, Collins M, Deng Y, El-Sharkawy RT, Côté F, Mallet J, Khan WI.

Gastroenterology. 2009 Nov;137(5):1649-60. doi: 10.1053/j.gastro.2009.08.041. Epub 2009 Aug 23.

PMID:
19706294
3.

Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.

Kim JJ, Bridle BW, Ghia JE, Wang H, Syed SN, Manocha MM, Rengasamy P, Shajib MS, Wan Y, Hedlund PB, Khan WI.

J Immunol. 2013 May 1;190(9):4795-804. doi: 10.4049/jimmunol.1201887. Epub 2013 Apr 3.

4.

PepT1 expressed in immune cells has an important role in promoting the immune response during experimentally induced colitis.

Ayyadurai S, Charania MA, Xiao B, Viennois E, Merlin D.

Lab Invest. 2013 Aug;93(8):888-99. doi: 10.1038/labinvest.2013.77. Epub 2013 Jun 24.

5.

Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice.

Horino J, Fujimoto M, Terabe F, Serada S, Takahashi T, Soma Y, Tanaka K, Chinen T, Yoshimura A, Nomura S, Kawase I, Hayashi N, Kishimoto T, Naka T.

Int Immunol. 2008 Jun;20(6):753-62. doi: 10.1093/intimm/dxn033. Epub 2008 Apr 1.

PMID:
18381351
6.

Analysis of real-time serotonin (5-HT) availability during experimental colitis in mouse.

Bertrand PP, Barajas-Espinosa A, Neshat S, Bertrand RL, Lomax AE.

Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G446-55. doi: 10.1152/ajpgi.00318.2009. Epub 2009 Dec 17.

7.

Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus.

Ghia JE, Galeazzi F, Ford DC, Hogaboam CM, Vallance BA, Collins S.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G770-7. doi: 10.1152/ajpgi.00453.2007. Epub 2008 Jan 17.

8.

Role of metallothionein in murine experimental colitis.

Tsuji T, Naito Y, Takagi T, Kugai M, Yoriki H, Horie R, Fukui A, Mizushima K, Hirai Y, Katada K, Kamada K, Uchiyama K, Handa O, Konishi H, Yagi N, Ichikawa H, Yanagisawa R, Suzuki JS, Takano H, Satoh M, Yoshikawa T.

Int J Mol Med. 2013 May;31(5):1037-46. doi: 10.3892/ijmm.2013.1294. Epub 2013 Mar 6.

PMID:
23467591
9.

Investigating intestinal inflammation in DSS-induced model of IBD.

Kim JJ, Shajib MS, Manocha MM, Khan WI.

J Vis Exp. 2012 Feb 1;(60). pii: 3678. doi: 10.3791/3678.

10.

Blocking peripheral serotonin synthesis by telotristat etiprate (LX1032/LX1606) reduces severity of both chemical- and infection-induced intestinal inflammation.

Kim JJ, Wang H, Terc JD, Zambrowicz B, Yang QM, Khan WI.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G455-65. doi: 10.1152/ajpgi.00299.2014. Epub 2015 Jul 23.

11.

Serotonin activates dendritic cell function in the context of gut inflammation.

Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI.

Am J Pathol. 2011 Feb;178(2):662-71. doi: 10.1016/j.ajpath.2010.10.028.

12.

Interleukin-19 protects mice from innate-mediated colonic inflammation.

Azuma YT, Matsuo Y, Kuwamura M, Yancopoulos GD, Valenzuela DM, Murphy AJ, Nakajima H, Karow M, Takeuchi T.

Inflamm Bowel Dis. 2010 Jun;16(6):1017-28. doi: 10.1002/ibd.21151.

PMID:
19834971
13.

Clcn5 knockout mice exhibit novel immunomodulatory effects and are more susceptible to dextran sulfate sodium-induced colitis.

Alex P, Ye M, Zachos NC, Sipes J, Nguyen T, Suhodrev M, Gonzales L, Arora Z, Zhang T, Centola M, Guggino SE, Li X.

J Immunol. 2010 Apr 1;184(7):3988-96. doi: 10.4049/jimmunol.0901657. Epub 2010 Feb 24.

14.

Serotonin regulates innate immune responses of colon epithelial cells through Nox2-derived reactive oxygen species.

Regmi SC, Park SY, Ku SK, Kim JA.

Free Radic Biol Med. 2014 Apr;69:377-89. doi: 10.1016/j.freeradbiomed.2014.02.003. Epub 2014 Feb 11.

PMID:
24524998
15.

cEBP Homologous Protein Expression in Macrophages Regulates the Magnitude and Duration of IL-6 Expression and Dextran Sodium Sulfate Colitis.

Datta S, Barrera N, Pavicic PG Jr, Zhao C, Freeman M, Min B, Hamilton T.

J Interferon Cytokine Res. 2015 Oct;35(10):785-94. doi: 10.1089/jir.2014.0204. Epub 2015 Jul 2.

16.

Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis.

Demon D, Kuchmiy A, Fossoul A, Zhu Q, Kanneganti TD, Lamkanfi M.

Mucosal Immunol. 2014 Nov;7(6):1480-91. doi: 10.1038/mi.2014.36. Epub 2014 May 21. Erratum in: Mucosal Immunol. 2014 Nov;7(6):1504.

17.

Osteopontin as two-sided mediator of intestinal inflammation.

Heilmann K, Hoffmann U, Witte E, Loddenkemper C, Sina C, Schreiber S, Hayford C, Holzlöhner P, Wolk K, Tchatchou E, Moos V, Zeitz M, Sabat R, Günthert U, Wittig BM.

J Cell Mol Med. 2009 Jun;13(6):1162-74. doi: 10.1111/j.1582-4934.2008.00428.x. Epub 2008 Jul 4.

18.

Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis.

Nighot P, Al-Sadi R, Rawat M, Guo S, Watterson DM, Ma T.

Am J Physiol Gastrointest Liver Physiol. 2015 Dec 15;309(12):G988-97. doi: 10.1152/ajpgi.00256.2015. Epub 2015 Oct 29.

19.

MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis.

Araki A, Kanai T, Ishikura T, Makita S, Uraushihara K, Iiyama R, Totsuka T, Takeda K, Akira S, Watanabe M.

J Gastroenterol. 2005 Jan;40(1):16-23.

PMID:
15692785
20.

Interleukin-17 induces an atypical M2-like macrophage subpopulation that regulates intestinal inflammation.

Nishikawa K, Seo N, Torii M, Ma N, Muraoka D, Tawara I, Masuya M, Tanaka K, Takei Y, Shiku H, Katayama N, Kato T.

PLoS One. 2014 Sep 25;9(9):e108494. doi: 10.1371/journal.pone.0108494. eCollection 2014.

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