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Items: 1 to 20 of 271

1.

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population.

Kuo JZ, Sheu WH, Assimes TL, Hung YJ, Absher D, Chiu YF, Mak J, Wang JS, Kwon S, Hsu CC, Goodarzi MO, Lee IT, Knowles JW, Miller BE, Lee WJ, Juang JM, Wang TD, Guo X, Taylor KD, Chuang LM, Hsiung CA, Quertermous T, Rotter JI, Chen YD.

Diabetologia. 2013 Dec;56(12):2619-28. doi: 10.1007/s00125-013-3047-1.

2.

Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.

Wen J, Rönn T, Olsson A, Yang Z, Lu B, Du Y, Groop L, Ling C, Hu R.

PLoS One. 2010 Feb 10;5(2):e9153. doi: 10.1371/journal.pone.0009153.

3.

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

Wu Y, Li H, Loos RJ, Yu Z, Ye X, Chen L, Pan A, Hu FB, Lin X.

Diabetes. 2008 Oct;57(10):2834-42. doi: 10.2337/db08-0047.

4.

Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore.

Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

J Clin Endocrinol Metab. 2010 Jan;95(1):390-7. doi: 10.1210/jc.2009-0688.

PMID:
19892838
5.

Genetic variants on chromosome 6p21.1 and 6p22.3 are associated with type 2 diabetes risk: a case-control study in Han Chinese.

Lu F, Qian Y, Li H, Dong M, Lin Y, Du J, Lin Y, Chen J, Shen C, Jin G, Dai J, Hu Z, Shen H.

J Hum Genet. 2012 May;57(5):320-5. doi: 10.1038/jhg.2012.25.

PMID:
22437209
6.

Association of genetic variants with isolated fasting hyperglycaemia and isolated postprandial hyperglycaemia in a Han Chinese population.

Kong X, Hong J, Chen Y, Chen L, Zhao Z, Li Q, Ge J, Chen G, Guo X, Lu J, Weng J, Jia W, Ji L, Xiao J, Shan Z, Liu J, Tian H, Ji Q, Zhu D, Zhou Z, Shan G, Yang W.

PLoS One. 2013 Aug 19;8(8):e71399. doi: 10.1371/journal.pone.0071399.

7.

Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.

Ma RC, Hu C, Tam CH, Zhang R, Kwan P, Leung TF, Thomas GN, Go MJ, Hara K, Sim X, Ho JS, Wang C, Li H, Lu L, Wang Y, Li JW, Wang Y, Lam VK, Wang J, Yu W, Kim YJ, Ng DP, Fujita H, Panoutsopoulou K, Day-Williams AG, Lee HM, Ng AC, Fang YJ, Kong AP, Jiang F, Ma X, Hou X, Tang S, Lu J, Yamauchi T, Tsui SK, Woo J, Leung PC, Zhang X, Tang NL, Sy HY, Liu J, Wong TY, Lee JY, Maeda S, Xu G, Cherny SS, Chan TF, Ng MC, Xiang K, Morris AP; DIAGRAM Consortium., Keildson S; MuTHER Consortium., Hu R, Ji L, Lin X, Cho YS, Kadowaki T, Tai ES, Zeggini E, McCarthy MI, Hon KL, Baum L, Tomlinson B, So WY, Bao Y, Chan JC, Jia W.

Diabetologia. 2013 Jun;56(6):1291-305. doi: 10.1007/s00125-013-2874-4.

8.

Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

Sim X, Ong RT, Suo C, Tay WT, Liu J, Ng DP, Boehnke M, Chia KS, Wong TY, Seielstad M, Teo YY, Tai ES.

PLoS Genet. 2011 Apr;7(4):e1001363. doi: 10.1371/journal.pgen.1001363.

9.

Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies.

Herder C, Rathmann W, Strassburger K, Finner H, Grallert H, Huth C, Meisinger C, Gieger C, Martin S, Giani G, Scherbaum WA, Wichmann HE, Illig T.

Horm Metab Res. 2008 Oct;40(10):722-6. doi: 10.1055/s-2008-1078730.

PMID:
18597214
10.

Replication study of novel risk variants in six genes with type 2 diabetes and related quantitative traits in the Han Chinese lean individuals.

Bao XY, Peng B, Yang MS.

Mol Biol Rep. 2012 Mar;39(3):2447-54. doi: 10.1007/s11033-011-0995-8.

PMID:
21643948
11.

Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese.

Hu C, Zhang R, Wang C, Wang J, Ma X, Hou X, Lu J, Yu W, Jiang F, Bao Y, Xiang K, Jia W.

PLoS One. 2010 Nov 17;5(11):e15542. doi: 10.1371/journal.pone.0015542.

12.
13.

Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.

Han X, Luo Y, Ren Q, Zhang X, Wang F, Sun X, Zhou X, Ji L.

BMC Med Genet. 2010 May 28;11:81. doi: 10.1186/1471-2350-11-81.

14.

Positive Association Between Type 2 Diabetes Risk Alleles Near CDKAL1 and Reduced Birthweight in Chinese Han Individuals.

Sun XF, Xiao XH, Zhang ZX, Liu Y, Xu T, Zhu XL, Zhang Y, Wu XP, Li WH, Zhang HB, Yu M.

Chin Med J (Engl). 2015 Jul 20;128(14):1873-8. doi: 10.4103/0366-6999.160489.

15.

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.

Omori S, Tanaka Y, Takahashi A, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Nakamura Y, Maeda S.

Diabetes. 2008 Mar;57(3):791-5.

16.

The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CDKAL1, JAZF1, and IGF1 genes.

Song M, Zhao F, Ran L, Dolikun M, Wu L, Ge S, Dong H, Gao Q, Zhai Y, Zhang L, Yan Y, Liu F, Yang X, Guo X, Wang Y, Wang W.

OMICS. 2015 Apr;19(4):230-7. doi: 10.1089/omi.2014.0162.

17.

Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort.

Chang YC, Chiu YF, Liu PH, Shih KC, Lin MW, Sheu WH, Quertermous T, Curb JD, Hsiung CA, Lee WJ, Lee PC, Chen YT, Chuang LM.

Clin Endocrinol (Oxf). 2012 Mar;76(3):365-72. doi: 10.1111/j.1365-2265.2011.04175.x.

PMID:
21767287
18.

Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians.

Chauhan G, Spurgeon CJ, Tabassum R, Bhaskar S, Kulkarni SR, Mahajan A, Chavali S, Kumar MV, Prakash S, Dwivedi OP, Ghosh S, Yajnik CS, Tandon N, Bharadwaj D, Chandak GR.

Diabetes. 2010 Aug;59(8):2068-74. doi: 10.2337/db09-1386.

19.

The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes.

Kong X, Zhang X, Xing X, Zhang B, Hong J, Yang W.

PLoS One. 2015 Nov 24;10(11):e0143607. doi: 10.1371/journal.pone.0143607.

20.

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

Diabetes. 2009 Jul;58(7):1690-9. doi: 10.2337/db08-1494.

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