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Items: 1 to 20 of 160

1.

Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.

Bonnavion R, Jaafar R, Kerr-Conte J, Assade F, van Stralen E, Leteurtre E, Pouponnot C, Gargani S, Pattou F, Bertolino P, Cordier-Bussat M, Lu J, Zhang CX.

PLoS One. 2013 Aug 27;8(8):e72194. doi: 10.1371/journal.pone.0072194. eCollection 2013.

2.

In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.

Hu He KH, Lorenzo PI, Brun T, Jimenez Moreno CM, Aeberhard D, Vallejo Ortega J, Cornu M, Thorel F, Gjinovci A, Thorens B, Herrera PL, Meda P, Wollheim CB, Gauthier BR.

Diabetes. 2011 Jun;60(6):1705-15. doi: 10.2337/db10-1102. Epub 2011 Apr 26.

3.

The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.

Brun T, Hu He KH, Lupi R, Boehm B, Wojtusciszyn A, Sauter N, Donath M, Marchetti P, Maedler K, Gauthier BR.

Hum Mol Genet. 2008 Feb 15;17(4):478-89. Epub 2007 Nov 7.

PMID:
17989064
4.

MafA is critical for maintenance of the mature beta cell phenotype in mice.

Nishimura W, Takahashi S, Yasuda K.

Diabetologia. 2015 Mar;58(3):566-74. doi: 10.1007/s00125-014-3464-9. Epub 2014 Dec 13.

PMID:
25500951
5.

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

Artner I, Le Lay J, Hang Y, Elghazi L, Schisler JC, Henderson E, Sosa-Pineda B, Stein R.

Diabetes. 2006 Feb;55(2):297-304.

6.

A novel function of Onecut1 protein as a negative regulator of MafA gene expression.

Yamamoto K, Matsuoka TA, Kawashima S, Takebe S, Kubo F, Miyatsuka T, Kaneto H, Shimomura I.

J Biol Chem. 2013 Jul 26;288(30):21648-58. doi: 10.1074/jbc.M113.481424. Epub 2013 Jun 17. Erratum in: J Biol Chem. 2013 Oct 25;288(43):31298. Kubo, Noriyo [corrected to Kubo, Fumiyo].

7.

Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression.

Djiotsa J, Verbruggen V, Giacomotto J, Ishibashi M, Manning E, Rinkwitz S, Manfroid I, Voz ML, Peers B.

BMC Dev Biol. 2012 Dec 17;12:37. doi: 10.1186/1471-213X-12-37.

8.

[Neurogenin 3 and Paired box gene 4 promote PDX1-induced differentiation of mesenchymal stem cells into pancreatic secretory cells].

Tang XL, Xiao R, Wang YX, He M, Xie T, Zhang C, Liu SJ.

Beijing Da Xue Xue Bao. 2011 Jun 18;43(3):421-6. Chinese.

9.

A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells.

Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S, Sharma A.

Dev Biol. 2006 May 15;293(2):526-39. Epub 2006 Apr 3.

10.

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells.

Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, Stein R.

Mol Cell Biol. 2003 Sep;23(17):6049-62.

11.

Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.

Al-Hasani K, Pfeifer A, Courtney M, Ben-Othman N, Gjernes E, Vieira A, Druelle N, Avolio F, Ravassard P, Leuckx G, Lacas-Gervais S, Ambrosetti D, Benizri E, Hecksher-Sorensen J, Gounon P, Ferrer J, Gradwohl G, Heimberg H, Mansouri A, Collombat P.

Dev Cell. 2013 Jul 15;26(1):86-100. doi: 10.1016/j.devcel.2013.05.018. Epub 2013 Jun 27.

12.

The temporal and hierarchical control of transcription factors-induced liver to pancreas transdifferentiation.

Berneman-Zeitouni D, Molakandov K, Elgart M, Mor E, Fornoni A, Domínguez MR, Kerr-Conte J, Ott M, Meivar-Levy I, Ferber S.

PLoS One. 2014 Feb 4;9(2):e87812. doi: 10.1371/journal.pone.0087812. eCollection 2014.

13.

Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes.

Kooptiwut S, Plengvidhya N, Chukijrungroat T, Sujjitjoon J, Semprasert N, Furuta H, Yenchitsomanus PT.

J Diabetes Complications. 2012 Jul-Aug;26(4):343-7. doi: 10.1016/j.jdiacomp.2012.03.025. Epub 2012 Apr 20.

PMID:
22521316
14.

Activins A and B Regulate Fate-Determining Gene Expression in Islet Cell Lines and Islet Cells From Male Mice.

Andrzejewski D, Brown ML, Ungerleider N, Burnside A, Schneyer AL.

Endocrinology. 2015 Jul;156(7):2440-50. doi: 10.1210/en.2015-1167. Epub 2015 May 11.

PMID:
25961841
15.

MafA and MafB activity in pancreatic β cells.

Hang Y, Stein R.

Trends Endocrinol Metab. 2011 Sep;22(9):364-73. doi: 10.1016/j.tem.2011.05.003. Epub 2011 Jun 28. Review.

16.

ATF2 interacts with beta-cell-enriched transcription factors, MafA, Pdx1, and beta2, and activates insulin gene transcription.

Han SI, Yasuda K, Kataoka K.

J Biol Chem. 2011 Mar 25;286(12):10449-56. doi: 10.1074/jbc.M110.209510. Epub 2011 Jan 28.

17.

Programming of human umbilical cord mesenchymal stem cells in vitro to promote pancreatic gene expression.

Wang H, Yang Y, Ho G, Lin X, Wu W, Li W, Lin L, Feng X, Huo X, Jiang J, Liu X, Huang T, Wei C, Ma L.

Mol Med Rep. 2013 Sep;8(3):769-74. doi: 10.3892/mmr.2013.1598. Epub 2013 Jul 23.

PMID:
23900717
18.

Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.

Hunter CS, Maestro MA, Raum JC, Guo M, Thompson FH 3rd, Ferrer J, Stein R.

Mol Endocrinol. 2011 Feb;25(2):339-47. doi: 10.1210/me.2010-0362. Epub 2010 Dec 30.

19.

Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas.

Lima MJ, Docherty HM, Chen Y, Vallier L, Docherty K.

PLoS One. 2012;7(5):e36481. doi: 10.1371/journal.pone.0036481. Epub 2012 May 1.

20.

Beta cell nuclear musculoaponeurotic fibrosarcoma oncogene family A (MafA) is deficient in type 2 diabetes.

Butler AE, Robertson RP, Hernandez R, Matveyenko AV, Gurlo T, Butler PC.

Diabetologia. 2012 Nov;55(11):2985-8. doi: 10.1007/s00125-012-2666-2. Epub 2012 Jul 31.

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