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Items: 1 to 20 of 122


Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2.

Yin F, Yu J, Zheng Y, Chen Q, Zhang N, Pan D.

Cell. 2013 Sep 12;154(6):1342-55. doi: 10.1016/j.cell.2013.08.025. Epub 2013 Sep 5.


Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade.

Zheng Y, Wang W, Liu B, Deng H, Uster E, Pan D.

Dev Cell. 2015 Sep 28;34(6):642-55. doi: 10.1016/j.devcel.2015.08.014. Epub 2015 Sep 10.


The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded.

Ling C, Zheng Y, Yin F, Yu J, Huang J, Hong Y, Wu S, Pan D.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10532-7. doi: 10.1073/pnas.1004279107. Epub 2010 May 24.


Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway.

Li Y, Zhou H, Li F, Chan SW, Lin Z, Wei Z, Yang Z, Guo F, Lim CJ, Xing W, Shen Y, Hong W, Long J, Zhang M.

Cell Res. 2015 Jul;25(7):801-17. doi: 10.1038/cr.2015.69. Epub 2015 Jun 5.


The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

Willecke M, Hamaratoglu F, Kango-Singh M, Udan R, Chen CL, Tao C, Zhang X, Halder G.

Curr Biol. 2006 Nov 7;16(21):2090-100. Epub 2006 Sep 21.


Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded.

Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D.

Dev Cell. 2010 Feb 16;18(2):288-99. doi: 10.1016/j.devcel.2009.12.012.


Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling.

Reddy BV, Irvine KD.

Development. 2011 Dec;138(23):5201-12. doi: 10.1242/dev.069385.


The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth.

Hamaratoglu F, Gajewski K, Sansores-Garcia L, Morrison C, Tao C, Halder G.

J Cell Sci. 2009 Jul 15;122(Pt 14):2351-9. doi: 10.1242/jcs.046482. Epub 2009 Jun 16.


Dmp53 activates the Hippo pathway to promote cell death in response to DNA damage.

Colombani J, Polesello C, Josué F, Tapon N.

Curr Biol. 2006 Jul 25;16(14):1453-8.


The Drosophila RASSF homolog antagonizes the hippo pathway.

Polesello C, Huelsmann S, Brown NH, Tapon N.

Curr Biol. 2006 Dec 19;16(24):2459-65.


Spectrin regulates Hippo signaling by modulating cortical actomyosin activity.

Deng H, Wang W, Yu J, Zheng Y, Qing Y, Pan D.

Elife. 2015 Mar 31;4:e06567. doi: 10.7554/eLife.06567.


Hippo pathway phylogenetics predicts monoubiquitylation of Salvador and Merlin/Nf2.

Wisotzkey RG, Konikoff CE, Newfeld SJ.

PLoS One. 2012;7(12):e51599. doi: 10.1371/journal.pone.0051599. Epub 2012 Dec 14.


The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis.

Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G.

Nat Cell Biol. 2006 Jan;8(1):27-36. Epub 2005 Dec 11. Erratum in: Nat Cell Biol. 2006 Jan;8(1):100.


The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway.

Yue T, Tian A, Jiang J.

Dev Cell. 2012 Feb 14;22(2):255-67. doi: 10.1016/j.devcel.2011.12.011. Epub 2012 Jan 25.


Binary regulation of Hippo pathway by Merlin/NF2, Kibra, Lgl, and Melted specifies and maintains postmitotic neuronal fate.

Jukam D, Desplan C.

Dev Cell. 2011 Nov 15;21(5):874-87. doi: 10.1016/j.devcel.2011.10.004. Epub 2011 Nov 3.


Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling.

Yan Y, Denef N, Tang C, Schüpbach T.

Development. 2011 May;138(9):1697-703. doi: 10.1242/dev.059279. Epub 2011 Mar 23.


Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants.

Benseñor LB, Barlan K, Rice SE, Fehon RG, Gelfand VI.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7311-6. doi: 10.1073/pnas.0907389107. Epub 2010 Apr 5.


Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.

Sekido Y.

Pathol Int. 2011 Jun;61(6):331-44. doi: 10.1111/j.1440-1827.2011.02666.x. Epub 2011 May 2. Review.


Merlin/NF2-Lin28B-let-7 Is a Tumor-Suppressive Pathway that Is Cell-Density Dependent and Hippo Independent.

Hikasa H, Sekido Y, Suzuki A.

Cell Rep. 2016 Mar 29;14(12):2950-61. doi: 10.1016/j.celrep.2016.02.075. Epub 2016 Mar 17.

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