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Items: 1 to 20 of 121

1.

Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist.

Kim HY, Goo JH, Joo YA, Lee HY, Lee SM, Oh CT, Ahn SM, Kim NH, Hwang JS.

Biomol Ther (Seoul). 2012 Sep;20(5):463-9. doi: 10.4062/biomolther.2012.20.5.463.

2.

Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid.

Joo YA, Chung H, Yoon S, Park JI, Lee JE, Myung CH, Hwang JS.

Biomol Ther (Seoul). 2016 Sep 1;24(5):529-35. doi: 10.4062/biomolther.2016.011.

3.

Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis.

Gaffal E, Glodde N, Jakobs M, Bald T, Tüting T.

Exp Dermatol. 2014 Jun;23(6):401-6. doi: 10.1111/exd.12414.

PMID:
24750433
4.

Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B.

Buddenkotte J, Stroh C, Engels IH, Moormann C, Shpacovitch VM, Seeliger S, Vergnolle N, Vestweber D, Luger TA, Schulze-Osthoff K, Steinhoff M.

J Invest Dermatol. 2005 Jan;124(1):38-45.

6.

Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery.

Jeong SK, Kim HJ, Youm JK, Ahn SK, Choi EH, Sohn MH, Kim KE, Hong JH, Shin DM, Lee SH.

J Invest Dermatol. 2008 Aug;128(8):1930-9. doi: 10.1038/jid.2008.13. Epub 2008 Feb 28.

7.

A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin.

Vestergaard C, Bang K, Gesser B, Yoneyama H, Matsushima K, Larsen CG.

J Invest Dermatol. 2000 Oct;115(4):640-6.

8.

Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice.

Wang Z, Zhang LJ, Guha G, Li S, Kyrylkova K, Kioussi C, Leid M, Ganguli-Indra G, Indra AK.

PLoS One. 2012;7(12):e51262. doi: 10.1371/journal.pone.0051262. Epub 2012 Dec 20.

9.

A synthetic C16 omega-hydroxyphytoceramide improves skin barrier functions from diversely perturbed epidermal conditions.

Oh MJ, Nam JJ, Lee EO, Kim JW, Park CS.

Arch Dermatol Res. 2016 Oct;308(8):563-74. doi: 10.1007/s00403-016-1674-3. Epub 2016 Jul 11.

PMID:
27402316
10.

Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.

Briot A, Deraison C, Lacroix M, Bonnart C, Robin A, Besson C, Dubus P, Hovnanian A.

J Exp Med. 2009 May 11;206(5):1135-47. doi: 10.1084/jem.20082242. Epub 2009 May 4.

11.

Panduratin A, an activator of PPAR-α/δ, suppresses the development of oxazolone-induced atopic dermatitis-like symptoms in hairless mice.

Kim MS, Pyun HB, Hwang JK.

Life Sci. 2014 Mar 28;100(1):45-54. doi: 10.1016/j.lfs.2014.01.076. Epub 2014 Feb 11.

PMID:
24530874
12.

Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin.

Kim S, Hong I, Hwang JS, Choi JK, Rho HS, Kim DH, Chang I, Lee SH, Lee MO, Hwang JS.

Mol Med. 2006 Jan-Mar;12(1-3):17-24.

13.

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.

Franzke CW, Cobzaru C, Triantafyllopoulou A, Löffek S, Horiuchi K, Threadgill DW, Kurz T, van Rooijen N, Bruckner-Tuderman L, Blobel CP.

J Exp Med. 2012 Jun 4;209(6):1105-19. doi: 10.1084/jem.20112258. Epub 2012 May 7. Erratum in: J Exp Med. 2012 Dec 17;209(13):2517.

14.

Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis.

Lee SE, Jeong SK, Lee SH.

Yonsei Med J. 2010 Nov;51(6):808-22. doi: 10.3349/ymj.2010.51.6.808. Review.

15.

Protease-activated receptor-2 induces proinflammatory cytokine and chemokine gene expression in canine keratinocytes.

Maeda S, Maeda S, Ohno K, Kaji N, Hori M, Fujino Y, Tsujimoto H.

Vet Immunol Immunopathol. 2013 May 15;153(1-2):17-25. doi: 10.1016/j.vetimm.2013.01.018. Epub 2013 Feb 13.

PMID:
23465358
16.

Inhibitory effect of 5,6-dihydroergosteol-glucoside on atopic dermatitis-like skin lesions via suppression of NF-κB and STAT activation.

Jung M, Lee TH, Oh HJ, Kim H, Son Y, Lee EH, Kim J.

J Dermatol Sci. 2015 Sep;79(3):252-61. doi: 10.1016/j.jdermsci.2015.06.005. Epub 2015 Jun 15.

PMID:
26100037
17.

Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.

Zhu Y, Underwood J, Macmillan D, Shariff L, O'Shaughnessy R, Harper JI, Pickard C, Friedmann PS, Healy E, Di WL.

J Allergy Clin Immunol. 2017 Nov;140(5):1310-1322.e5. doi: 10.1016/j.jaci.2017.01.025. Epub 2017 Feb 24.

PMID:
28238749
18.

Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model.

Jang H, Matsuda A, Jung K, Karasawa K, Matsuda K, Oida K, Ishizaka S, Ahn G, Amagai Y, Moon C, Kim SH, Arkwright PD, Takamori K, Matsuda H, Tanaka A.

J Invest Dermatol. 2016 Jan;136(1):127-35. doi: 10.1038/JID.2015.363.

19.

The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling.

Amano W, Nakajima S, Kunugi H, Numata Y, Kitoh A, Egawa G, Dainichi T, Honda T, Otsuka A, Kimoto Y, Yamamoto Y, Tanimoto A, Matsushita M, Miyachi Y, Kabashima K.

J Allergy Clin Immunol. 2015 Sep;136(3):667-677.e7. doi: 10.1016/j.jaci.2015.03.051. Epub 2015 Jun 24.

PMID:
26115905
20.

SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.

Sivaprasad U, Kinker KG, Ericksen MB, Lindsey M, Gibson AM, Bass SA, Hershey NS, Deng J, Medvedovic M, Khurana Hershey GK.

J Invest Dermatol. 2015 Jan;135(1):160-169. doi: 10.1038/jid.2014.353. Epub 2014 Aug 11.

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