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IRS1 genotype modulates metabolic syndrome reversion in response to 2-year weight-loss diet intervention: the POUNDS LOST trial.

Qi Q, Xu M, Wu H, Liang L, Champagne CM, Bray GA, Sacks FM, Qi L.

Diabetes Care. 2013 Nov;36(11):3442-7. doi: 10.2337/dc13-0018. Epub 2013 Sep 5.


Vitamin D metabolism-related genetic variants, dietary protein intake and improvement of insulin resistance in a 2 year weight-loss trial: POUNDS Lost.

Qi Q, Zheng Y, Huang T, Rood J, Bray GA, Sacks FM, Qi L.

Diabetologia. 2015 Dec;58(12):2791-9. doi: 10.1007/s00125-015-3750-1. Epub 2015 Sep 29.


APOA5 genotype modulates 2-y changes in lipid profile in response to weight-loss diet intervention: the Pounds Lost Trial.

Zhang X, Qi Q, Bray GA, Hu FB, Sacks FM, Qi L.

Am J Clin Nutr. 2012 Oct;96(4):917-22. Epub 2012 Aug 22.


Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity.

Zheng Y, Huang T, Zhang X, Rood J, Bray GA, Sacks FM, Qi L.

J Nutr. 2015 May;145(5):977-82. doi: 10.3945/jn.115.210005. Epub 2015 Mar 11.


Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries.

Zheng JS, Arnett DK, Parnell LD, Smith CE, Li D, Borecki IB, Tucker KL, Ordovás JM, Lai CQ.

Diabetes Care. 2013 Sep;36(9):2621-7. doi: 10.2337/dc12-2607. Epub 2013 Apr 17.


Genetic determinant for amino acid metabolites and changes in body weight and insulin resistance in response to weight-loss diets: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial.

Xu M, Qi Q, Liang J, Bray GA, Hu FB, Sacks FM, Qi L.

Circulation. 2013 Mar 26;127(12):1283-9. doi: 10.1161/CIRCULATIONAHA.112.000586. Epub 2013 Feb 27.


Sex-specific interactions between the IRS1 polymorphism and intakes of carbohydrates and fat on incident type 2 diabetes.

Ericson U, Rukh G, Stojkovic I, Sonestedt E, Gullberg B, Wirfält E, Wallström P, Orho-Melander M.

Am J Clin Nutr. 2013 Jan;97(1):208-16. doi: 10.3945/ajcn.112.046474. Epub 2012 Dec 5.


Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.

Santos JL, De la Cruz R, Holst C, Grau K, Naranjo C, Maiz A, Astrup A, Saris WH, MacDonald I, Oppert JM, Hansen T, Pedersen O, Sorensen TI, Martinez JA; NUGENOB Consortium.

PLoS One. 2011;6(6):e19934. doi: 10.1371/journal.pone.0019934. Epub 2011 Jun 14.


FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.

Zhang X, Qi Q, Zhang C, Smith SR, Hu FB, Sacks FM, Bray GA, Qi L.

Diabetes. 2012 Nov;61(11):3005-11. doi: 10.2337/db11-1799. Epub 2012 Aug 13. Erratum in: Diabetes. 2013 Feb;62(2):662. Smith, Steven R [added]; Bray, George A [added].


Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans.

Grau K, Hansen T, Holst C, Astrup A, Saris WH, Arner P, Rössner S, Macdonald I, Polak J, Oppert JM, Langin D, Martinez JA, Pedersen O, Sørensen TI.

Int J Obes (Lond). 2009 Nov;33(11):1227-34. doi: 10.1038/ijo.2009.159. Epub 2009 Aug 18.


Effect of low-fat and/or low-energy diets on anthropometric measures in participants of the women's diet study.

Djuric Z, Lababidi S, Heilbrun LK, Depper JB, Poore KM, Uhley VE.

J Am Coll Nutr. 2002 Feb;21(1):38-46.


PCSK7 genotype modifies effect of a weight-loss diet on 2-year changes of insulin resistance: the POUNDS LOST trial.

Huang T, Huang J, Qi Q, Li Y, Bray GA, Rood J, Sacks FM, Qi L.

Diabetes Care. 2015 Mar;38(3):439-44. doi: 10.2337/dc14-0473. Epub 2014 Dec 12.


The - 11391 G/A polymorphism of the adiponectin gene promoter is associated with metabolic syndrome traits and the outcome of an energy-restricted diet in obese subjects.

Goyenechea E, Collins LJ, Parra D, Abete I, Crujeiras AB, O'Dell SD, Martínez JA.

Horm Metab Res. 2009 Jan;41(1):55-61. doi: 10.1055/s-0028-1087204. Epub 2008 Oct 23.


Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study.

Yubero-Serrano EM, Delgado-Lista J, Tierney AC, Perez-Martinez P, Garcia-Rios A, Alcala-Diaz JF, Castaño JP, Tinahones FJ, Drevon CA, Defoort C, Blaak EE, Dembinska-Kieć A, Risérus U, Lovegrove JA, Perez-Jimenez F, Roche HM, Lopez-Miranda J.

Am J Clin Nutr. 2015 Dec;102(6):1509-17. doi: 10.3945/ajcn.115.111286. Epub 2015 Nov 11.


The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial.

Stern L, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, Williams M, Gracely EJ, Samaha FF.

Ann Intern Med. 2004 May 18;140(10):778-85.


Effect of the glycemic index of the diet on weight loss, modulation of satiety, inflammation, and other metabolic risk factors: a randomized controlled trial.

Juanola-Falgarona M, Salas-Salvadó J, Ibarrola-Jurado N, Rabassa-Soler A, Díaz-López A, Guasch-Ferré M, Hernández-Alonso P, Balanza R, Bulló M.

Am J Clin Nutr. 2014 Jul;100(1):27-35. doi: 10.3945/ajcn.113.081216. Epub 2014 Apr 30.


Variants in glucose- and circadian rhythm-related genes affect the response of energy expenditure to weight-loss diets: the POUNDS LOST Trial.

Mirzaei K, Xu M, Qi Q, de Jonge L, Bray GA, Sacks F, Qi L.

Am J Clin Nutr. 2014 Feb;99(2):392-9. doi: 10.3945/ajcn.113.072066. Epub 2013 Dec 11.

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