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Items: 1 to 20 of 106

1.

Structures and biogenetic analysis of lipofuscin bis-retinoids.

Wu YL, Li J, Yao K.

J Zhejiang Univ Sci B. 2013 Sep;14(9):763-73. doi: 10.1631/jzus.B1300051. Review.

2.

Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.

Boyer NP, Higbee D, Currin MB, Blakeley LR, Chen C, Ablonczy Z, Crouch RK, Koutalos Y.

J Biol Chem. 2012 Jun 22;287(26):22276-86. doi: 10.1074/jbc.M111.329235. Epub 2012 May 8.

3.
4.

Experimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epithelium.

Sparrow JR, Kim SR, Wu Y.

Methods Mol Biol. 2010;652:315-27. doi: 10.1007/978-1-60327-325-1_18.

5.

The bisretinoids of retinal pigment epithelium.

Sparrow JR, Gregory-Roberts E, Yamamoto K, Blonska A, Ghosh SK, Ueda K, Zhou J.

Prog Retin Eye Res. 2012 Mar;31(2):121-35. doi: 10.1016/j.preteyeres.2011.12.001. Epub 2011 Dec 22. Review.

6.

Bisretinoids of RPE lipofuscin: trigger for complement activation in age-related macular degeneration.

Sparrow JR.

Adv Exp Med Biol. 2010;703:63-74. doi: 10.1007/978-1-4419-5635-4_5. Review.

PMID:
20711707
7.

The bisretinoids of RPE lipofuscin: a complex mixture.

Sparrow JR, Yamamoto K.

Adv Exp Med Biol. 2012;723:761-7. doi: 10.1007/978-1-4614-0631-0_97. Review. No abstract available.

PMID:
22183404
8.

Preparative and biosynthetic insights into pdA2E and isopdA2E, retinal-derived fluorophores of retinal pigment epithelial lipofuscin.

Zhao J, Yao K, Jin Q, Jiang K, Chen J, Liu Z, Li J, Wu Y.

Invest Ophthalmol Vis Sci. 2014 Nov 20;55(12):8241-50. doi: 10.1167/iovs.14-15709.

PMID:
25414195
9.
10.

Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.

Radu RA, Hu J, Yuan Q, Welch DL, Makshanoff J, Lloyd M, McMullen S, Travis GH, Bok D.

J Biol Chem. 2011 May 27;286(21):18593-601. doi: 10.1074/jbc.M110.191866. Epub 2011 Apr 4.

11.

Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD).

Kaarniranta K, Salminen A, Eskelinen EL, Kopitz J.

Ageing Res Rev. 2009 Apr;8(2):128-39. Review.

PMID:
19274853
12.

Spatial localization of A2E in the retinal pigment epithelium.

Grey AC, Crouch RK, Koutalos Y, Schey KL, Ablonczy Z.

Invest Ophthalmol Vis Sci. 2011 Jun 6;52(7):3926-33. doi: 10.1167/iovs.10-7020.

13.

Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration.

Mata NL, Tzekov RT, Liu X, Weng J, Birch DG, Travis GH.

Invest Ophthalmol Vis Sci. 2001 Jul;42(8):1685-90.

PMID:
11431429
14.

Formation of lipofuscin-like material in the RPE Cell by different components of rod outer segments.

Lei L, Tzekov R, McDowell JH, Smith WC, Tang S, Kaushal S.

Exp Eye Res. 2013 Jul;112:57-67. doi: 10.1016/j.exer.2013.04.006. Epub 2013 Apr 18.

15.
16.

Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.

Zhou J, Ueda K, Zhao J, Sparrow JR.

J Biol Chem. 2015 Nov 6;290(45):27215-27. doi: 10.1074/jbc.M115.680363. Epub 2015 Sep 22.

17.

The 11-cis Retinal Origins of Lipofuscin in the Retina.

Adler L 4th, Boyer NP, Chen C, Ablonczy Z, Crouch RK, Koutalos Y.

Prog Mol Biol Transl Sci. 2015;134:e1-12. doi: 10.1016/bs.pmbts.2015.07.022. Review.

PMID:
26310175
18.

Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway.

Kim SR, He J, Yanase E, Jang YP, Berova N, Sparrow JR, Nakanishi K.

Biochemistry. 2007 Sep 4;46(35):10122-9. Epub 2007 Aug 8.

19.

[Detergent-like effects of the lipofuscin retinoid component A2-E in retinal pigment epithelial cells].

Schütt F, Bergmann M, Kopitz J, Holz FG.

Ophthalmologe. 2002 Nov;99(11):861-5. German.

PMID:
12430039
20.

Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration.

Kinnunen K, Petrovski G, Moe MC, Berta A, Kaarniranta K.

Acta Ophthalmol. 2012 Jun;90(4):299-309. doi: 10.1111/j.1755-3768.2011.02179.x. Epub 2011 Nov 23. Review.

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