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Items: 1 to 20 of 345

1.

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.

Fann DY, Lee SY, Manzanero S, Tang SC, Gelderblom M, Chunduri P, Bernreuther C, Glatzel M, Cheng YL, Thundyil J, Widiapradja A, Lok KZ, Foo SL, Wang YC, Li YI, Drummond GR, Basta M, Magnus T, Jo DG, Mattson MP, Sobey CG, Arumugam TV.

Cell Death Dis. 2013 Sep 5;4:e790. doi: 10.1038/cddis.2013.326.

2.

Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma.

Chi W, Li F, Chen H, Wang Y, Zhu Y, Yang X, Zhu J, Wu F, Ouyang H, Ge J, Weinreb RN, Zhang K, Zhuo Y.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11181-6. doi: 10.1073/pnas.1402819111. Epub 2014 Jul 14.

3.

Intermittent fasting attenuates inflammasome activity in ischemic stroke.

Fann DY, Santro T, Manzanero S, Widiapradja A, Cheng YL, Lee SY, Chunduri P, Jo DG, Stranahan AM, Mattson MP, Arumugam TV.

Exp Neurol. 2014 Jul;257:114-9. doi: 10.1016/j.expneurol.2014.04.017. Epub 2014 May 5.

PMID:
24805069
4.

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

Saresella M, La Rosa F, Piancone F, Zoppis M, Marventano I, Calabrese E, Rainone V, Nemni R, Mancuso R, Clerici M.

Mol Neurodegener. 2016 Mar 3;11:23. doi: 10.1186/s13024-016-0088-1.

5.

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.

Guey B, Bodnar M, Manié SN, Tardivel A, Petrilli V.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17254-9. doi: 10.1073/pnas.1415756111. Epub 2014 Nov 17.

6.

Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes.

Maier NK, Crown D, Liu J, Leppla SH, Moayeri M.

J Immunol. 2014 Jan 15;192(2):763-70. doi: 10.4049/jimmunol.1301434. Epub 2013 Dec 13.

7.

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.

Kaushal V, Dye R, Pakavathkumar P, Foveau B, Flores J, Hyman B, Ghetti B, Koller BH, LeBlanc AC.

Cell Death Differ. 2015 Oct;22(10):1676-86. doi: 10.1038/cdd.2015.16. Epub 2015 Mar 6.

8.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A.

Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10.

PMID:
23580606
9.

The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.

PMID:
23843215
10.

Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke.

Fann DY, Lim YA, Cheng YL, Lok KZ, Chunduri P, Baik SH, Drummond GR, Dheen ST, Sobey CG, Jo DG, Chen CL, Arumugam TV.

Mol Neurobiol. 2017 Jan 14. doi: 10.1007/s12035-017-0394-9. [Epub ahead of print]

PMID:
28092085
11.

The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.

Maier NK, Leppla SH, Moayeri M.

J Immunol. 2015 Mar 15;194(6):2776-85. doi: 10.4049/jimmunol.1401611. Epub 2015 Feb 13.

12.

Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin.

Xia M, Boini KM, Abais JM, Xu M, Zhang Y, Li PL.

Am J Pathol. 2014 May;184(5):1617-28. doi: 10.1016/j.ajpath.2014.01.032. Epub 2014 Mar 13.

13.

Role of the nucleotide-binding domain-like receptor protein 3 inflammasome in acute kidney injury.

Cao Y, Fei D, Chen M, Sun M, Xu J, Kang K, Jiang L, Zhao M.

FEBS J. 2015 Oct;282(19):3799-807. doi: 10.1111/febs.13379. Epub 2015 Aug 21.

14.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

15.

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.

Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.

Exp Eye Res. 2014 Aug;125:1-8. doi: 10.1016/j.exer.2014.05.001. Epub 2014 May 14.

PMID:
24836981
16.

NLRP3 inflammasome knockout mice are protected against ischemic but not cisplatin-induced acute kidney injury.

Kim HJ, Lee DW, Ravichandran K, O Keys D, Akcay A, Nguyen Q, He Z, Jani A, Ljubanovic D, Edelstein CL.

J Pharmacol Exp Ther. 2013 Sep;346(3):465-72. doi: 10.1124/jpet.113.205732. Epub 2013 Jul 5.

17.

The neuroprotection of Sinomenine against ischemic stroke in mice by suppressing NLRP3 inflammasome via AMPK signaling.

Qiu J, Wang M, Zhang J, Cai Q, Lu D, Li Y, Dong Y, Zhao T, Chen H.

Int Immunopharmacol. 2016 Nov;40:492-500. doi: 10.1016/j.intimp.2016.09.024. Epub 2016 Oct 18.

PMID:
27769021
18.

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.

He Y, Zeng MY, Yang D, Motro B, Núñez G.

Nature. 2016 Feb 18;530(7590):354-7. doi: 10.1038/nature16959. Epub 2016 Jan 27.

19.

Deregulated NLRP3 and NLRP1 inflammasomes and their correlations with disease activity in systemic lupus erythematosus.

Yang Q, Yu C, Yang Z, Wei Q, Mu K, Zhang Y, Zhao W, Wang X, Huai W, Han L.

J Rheumatol. 2014 Mar;41(3):444-52. doi: 10.3899/jrheum.130310. Epub 2013 Dec 15.

PMID:
24334646
20.

Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii.

Gorfu G, Cirelli KM, Melo MB, Mayer-Barber K, Crown D, Koller BH, Masters S, Sher A, Leppla SH, Moayeri M, Saeij JP, Grigg ME.

MBio. 2014 Feb 18;5(1). pii: e01117-13. doi: 10.1128/mBio.01117-13.

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