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Items: 1 to 20 of 167


Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells.

Tien T, Barrette KF, Chronopoulos A, Roy S.

Invest Ophthalmol Vis Sci. 2013 Oct 3;54(10):6518-25. doi: 10.1167/iovs.13-11763.


High glucose alters Cx43 expression and gap junction intercellular communication in retinal Müller cells: promotes Müller cell and pericyte apoptosis.

Muto T, Tien T, Kim D, Sarthy VP, Roy S.

Invest Ophthalmol Vis Sci. 2014 Jun 17;55(7):4327-37. doi: 10.1167/iovs.14-14606.


High glucose-induced downregulation of connexin 30.2 promotes retinal vascular lesions: implications for diabetic retinopathy.

Manasson J, Tien T, Moore C, Kumar NM, Roy S.

Invest Ophthalmol Vis Sci. 2013 Mar 28;54(3):2361-6. doi: 10.1167/iovs.12-10815.


High glucose-induced downregulation of connexin 43 expression promotes apoptosis in microvascular endothelial cells.

Li AF, Roy S.

Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1400-7. doi: 10.1167/iovs.07-1519. Epub 2008 Nov 21.


High glucose alters connexin 43 expression and gap junction intercellular communication activity in retinal pericytes.

Li AF, Sato T, Haimovici R, Okamoto T, Roy S.

Invest Ophthalmol Vis Sci. 2003 Dec;44(12):5376-82.


Benzalkonium chloride suppresses rabbit corneal endothelium intercellular gap junction communication.

Zhang Z, Huang Y, Xie H, Pan J, Liu F, Li X, Chen W, Hu J, Liu Z.

PLoS One. 2014 Oct 9;9(10):e109708. doi: 10.1371/journal.pone.0109708. eCollection 2014.


Effects of rhein on intestinal epithelial tight junction in IgA nephropathy.

Peng SN, Zeng HH, Fu AX, Chen XW, Zhu QX.

World J Gastroenterol. 2013 Jul 14;19(26):4137-45. doi: 10.3748/wjg.v19.i26.4137.


High glucose induces dysfunction of airway epithelial barrier through down-regulation of connexin 43.

Yu H, Yang J, Zhou X, Xiao Q, Lü Y, Xia L.

Exp Cell Res. 2016 Mar 1;342(1):11-9. doi: 10.1016/j.yexcr.2016.02.012. Epub 2016 Feb 19.


Beneficial effects of fenofibric acid on overexpression of extracellular matrix components, COX-2, and impairment of endothelial permeability associated with diabetic retinopathy.

Roy S, Kim D, Hernández C, Simó R, Roy S.

Exp Eye Res. 2015 Nov;140:124-9. doi: 10.1016/j.exer.2015.08.010. Epub 2015 Aug 18.


Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis.

Kim D, Mecham RP, Trackman PC, Roy S.

Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2725-2731. doi: 10.1167/iovs.16-21340.


Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.

Leal EC, Martins J, Voabil P, Liberal J, Chiavaroli C, Bauer J, Cunha-Vaz J, Ambrósio AF.

Diabetes. 2010 Oct;59(10):2637-45. doi: 10.2337/db09-1421. Epub 2010 Jul 13.


Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature.

Jiang Y, Liu L, Steinle JJ.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):185-189. doi: 10.1167/iovs.16-20412.


High glucose-induced altered basement membrane composition and structure increases trans-endothelial permeability: implications for diabetic retinopathy.

Chronopoulos A, Trudeau K, Roy S, Huang H, Vinores SA, Roy S.

Curr Eye Res. 2011 Aug;36(8):747-53. doi: 10.3109/02713683.2011.585735.


Connexin 26 expression prevents down-regulation of barrier and fence functions of tight junctions by Na+/K+-ATPase inhibitor ouabain in human airway epithelial cell line Calu-3.

Go M, Kojima T, Takano K, Murata M, Koizumi J, Kurose M, Kamekura R, Osanai M, Chiba H, Spray DC, Himi T, Sawada N.

Exp Cell Res. 2006 Nov 15;312(19):3847-56. Epub 2006 Aug 23.


Association of reduced Connexin 43 expression with retinal vascular lesions in human diabetic retinopathy.

Tien T, Muto T, Zhang J, Sohn EH, Mullins RF, Roy S.

Exp Eye Res. 2016 May;146:103-6. doi: 10.1016/j.exer.2015.12.011. Epub 2015 Dec 29. Review.


High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function.

Chronopoulos A, Tang A, Beglova E, Trackman PC, Roy S.

Diabetes. 2010 Dec;59(12):3159-66. doi: 10.2337/db10-0365. Epub 2010 Sep 7.


Regulation of IL-8 by Irsogladine maleate is involved in abolishment of Actinobacillus actinomycetemcomitans-induced reduction of gap-junctional intercellular communication.

Fujita T, Ashikaga A, Shiba H, Uchida Y, Hirono C, Iwata T, Takeda K, Kishimoto A, Hirata R, Kawaguchi H, Shiba Y, Kurihara H.

Cytokine. 2006 Jun;34(5-6):271-7. Epub 2006 Jul 25.


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