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Ziyuglycoside II inhibits the growth of human breast carcinoma MDA-MB-435 cells via cell cycle arrest and induction of apoptosis through the mitochondria dependent pathway.

Zhu X, Wang K, Zhang K, Huang B, Zhang J, Zhang Y, Zhu L, Zhou B, Zhou F.

Int J Mol Sci. 2013 Sep 3;14(9):18041-55. doi: 10.3390/ijms140918041.


Ziyuglycoside II induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells.

Zhu X, Wang K, Zhang K, Zhu L, Zhou F.

Toxicol Lett. 2014 May 16;227(1):65-73. doi: 10.1016/j.toxlet.2014.03.015.


Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/Bcl-2 expression and activating caspase-3 pathway.

Zhu AK, Zhou H, Xia JZ, Jin HC, Wang K, Yan J, Zuo JB, Zhu X, Shan T.

Braz J Med Biol Res. 2013 Aug;46(8):670-5. doi: 10.1590/1414-431X20133050.


ERK-modulated intrinsic signaling and G(2)/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells.

Tsai SC, Huang WW, Huang WC, Lu CC, Chiang JH, Peng SF, Chung JG, Lin YH, Hsu YM, Amagaya S, Yang JS.

Int J Oncol. 2012 Dec;41(6):2065-72. doi: 10.3892/ijo.2012.1640.


The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway.

Lee JH, Li YC, Ip SW, Hsu SC, Chang NW, Tang NY, Yu CS, Chou ST, Lin SS, Lino CC, Yang JS, Chung JG.

Anticancer Res. 2008 May-Jun;28(3A):1701-11.


Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells.

Chien SY, Wu YC, Chung JG, Yang JS, Lu HF, Tsou MF, Wood WG, Kuo SJ, Chen DR.

Hum Exp Toxicol. 2009 Aug;28(8):493-503. doi: 10.1177/0960327109107002.


Diallyl sulfide promotes cell-cycle arrest through the p53 expression and triggers induction of apoptosis via caspase- and mitochondria-dependent signaling pathways in human cervical cancer Ca Ski cells.

Chiu TH, Lan KY, Yang MD, Lin JJ, Hsia TC, Wu CT, Yang JS, Chueh FS, Chung JG.

Nutr Cancer. 2013;65(3):505-14. doi: 10.1080/01635581.2012.725503.


Bax translocation mediated mitochondrial apoptosis and caspase dependent photosensitizing effect of Ficus religiosa on cancer cells.

Haneef J, Parvathy M, Thankayyan R SK, Sithul H, Sreeharshan S.

PLoS One. 2012;7(7):e40055. doi: 10.1371/journal.pone.0040055. Erratum in: PLoS One. 2012;7(10):doi/10.1371/annotation/ab341223-61ed-4b19-95c7-21455c321e06. M, Parvathy [corrected to Parvathy, Muraleedharan].


A novel trifluoromethyl benzopyran induces G1 cell cycle arrest and apoptosis in HeLa human cervical carcinoma cells.

Zhang X, Hwang J, Jia X, Shin DS, You S, Kim DK.

Int J Oncol. 2013 Aug;43(2):469-76. doi: 10.3892/ijo.2013.1958.


Induction of apoptosis in human breast cancer cells via caspase pathway by vernodalin isolated from Centratherum anthelminticum (L.) seeds.

Looi CY, Arya A, Cheah FK, Muharram B, Leong KH, Mohamad K, Wong WF, Rai N, Mustafa MR.

PLoS One. 2013;8(2):e56643. doi: 10.1371/journal.pone.0056643.


Chamaejasmine induces apoptosis in human lung adenocarcinoma A549 cells through a Ros-mediated mitochondrial pathway.

Yu H, Zhang T, Cai L, Qu Y, Hu S, Dong G, Guan R, Xu X, Xing L.

Molecules. 2011 Sep 27;16(10):8165-80. doi: 10.3390/molecules16108165.


Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v.


Anti-tumor potential of 15,16-dihydrotanshinone I against breast adenocarcinoma through inducing G1 arrest and apoptosis.

Tsai SL, Suk FM, Wang CI, Liu DZ, Hou WC, Lin PJ, Hung LF, Liang YC.

Biochem Pharmacol. 2007 Dec 3;74(11):1575-86.


Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis.

Zhong Z, Chen X, Tan W, Xu Z, Zhou K, Wu T, Cui L, Wang Y.

Eur J Pharmacol. 2011 Sep 30;667(1-3):50-5. doi: 10.1016/j.ejphar.2011.03.041.


Dioscin, a natural steroid saponin, induces apoptosis and DNA damage through reactive oxygen species: a potential new drug for treatment of glioblastoma multiforme.

Lv L, Zheng L, Dong D, Xu L, Yin L, Xu Y, Qi Y, Han X, Peng J.

Food Chem Toxicol. 2013 Sep;59:657-69. doi: 10.1016/j.fct.2013.07.012.


Curcumin inhibits proliferation and induces apoptosis of human colorectal cancer cells by activating the mitochondria apoptotic pathway.

Guo LD, Chen XJ, Hu YH, Yu ZJ, Wang D, Liu JZ.

Phytother Res. 2013 Mar;27(3):422-30. doi: 10.1002/ptr.4731.


Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis.

Zhang N, Kong X, Yan S, Yuan C, Yang Q.

Cancer Sci. 2010 Nov;101(11):2375-83. doi: 10.1111/j.1349-7006.2010.01680.x.


SFE-CO2 extract from Typhonium giganteum Engl. tubers, induces apoptosis in human hepatoma SMMC-7721 cells involvement of a ROS-mediated mitochondrial pathway.

Li Q, Jiang C, Zu Y, Song Z, Zhang B, Meng X, Qiu W, Zhang L.

Molecules. 2011 Sep 28;16(10):8228-42. doi: 10.3390/molecules16108228.

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