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Items: 1 to 20 of 367

1.

Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes.

Kim MS, Lee KT, Iseli TJ, Hoy AJ, George J, Grewal T, Roufogalis BD.

Liver Int. 2013 Nov;33(10):1583-93. doi: 10.1111/liv.12287. Epub 2013 Sep 2.

PMID:
23998390
2.

Alisol A 24-Acetate Prevents Hepatic Steatosis and Metabolic Disorders in HepG2 Cells.

Zeng L, Tang W, Yin J, Feng L, Li Y, Yao X, Zhou B.

Cell Physiol Biochem. 2016;40(3-4):453-464. Epub 2016 Nov 25.

3.

Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes.

Kang OH, Kim SB, Mun SH, Seo YS, Hwang HC, Lee YM, Lee HS, Kang DG, Kwon DY.

Int J Mol Med. 2015 Mar;35(3):803-9. doi: 10.3892/ijmm.2015.2074. Epub 2015 Jan 21.

PMID:
25605057
4.

Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARα pathways in L02 cells and HepG2 cells.

Yin J, Luo Y, Deng H, Qin S, Tang W, Zeng L, Zhou B.

J Ethnopharmacol. 2014 May 28;154(1):229-39. doi: 10.1016/j.jep.2014.04.011. Epub 2014 Apr 13.

PMID:
24735863
5.

Honokiol activates the LKB1-AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes.

Seo MS, Kim JH, Kim HJ, Chang KC, Park SW.

Toxicol Appl Pharmacol. 2015 Apr 15;284(2):113-24. doi: 10.1016/j.taap.2015.02.020. Epub 2015 Feb 28.

PMID:
25737164
7.

Water Extract of Dolichos lablab Attenuates Hepatic Lipid Accumulation in a Cellular Nonalcoholic Fatty Liver Disease Model.

Im AR, Kim YH, Lee HW, Song KH.

J Med Food. 2016 May;19(5):495-503. doi: 10.1089/jmf.2015.3623.

PMID:
27152979
8.

A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis.

Wallstab C, Eleftheriadou D, Schulz T, Damm G, Seehofer D, Borlak J, Holzhütter HG, Berndt N.

FEBS J. 2017 Oct;284(19):3245-3261. doi: 10.1111/febs.14189. Epub 2017 Sep 6.

PMID:
28763157
9.

Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice.

Hsu WH, Chen TH, Lee BH, Hsu YW, Pan TM.

Food Chem Toxicol. 2014 Feb;64:94-103. doi: 10.1016/j.fct.2013.11.015. Epub 2013 Nov 22.

PMID:
24275089
10.

PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells.

Rogue A, Anthérieu S, Vluggens A, Umbdenstock T, Claude N, de la Moureyre-Spire C, Weaver RJ, Guillouzo A.

Toxicol Appl Pharmacol. 2014 Apr 1;276(1):73-81. doi: 10.1016/j.taap.2014.02.001. Epub 2014 Feb 15.

11.

Direct effects of iodothyronines on excess fat storage in rat hepatocytes.

Grasselli E, Voci A, Canesi L, De Matteis R, Goglia F, Cioffi F, Fugassa E, Gallo G, Vergani L.

J Hepatol. 2011 Jun;54(6):1230-6. doi: 10.1016/j.jhep.2010.09.027. Epub 2010 Nov 3.

PMID:
21145833
12.

Non-esterified fatty acids activate the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes.

Li X, Li X, Chen H, Lei L, Liu J, Guan Y, Liu Z, Zhang L, Yang W, Zhao C, Fu S, Li P, Liu G, Wang Z.

Cell Biochem Biophys. 2013;67(3):1157-69. doi: 10.1007/s12013-013-9629-1.

PMID:
23690240
13.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
14.

Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis.

Svegliati-Baroni G, Saccomanno S, Rychlicki C, Agostinelli L, De Minicis S, Candelaresi C, Faraci G, Pacetti D, Vivarelli M, Nicolini D, Garelli P, Casini A, Manco M, Mingrone G, Risaliti A, Frega GN, Benedetti A, Gastaldelli A.

Liver Int. 2011 Oct;31(9):1285-97. doi: 10.1111/j.1478-3231.2011.02462.x. Epub 2011 Feb 15.

PMID:
21745271
15.

Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK-mTOR-SREBP signaling pathway.

Quan HY, Kim DY, Kim SJ, Jo HK, Kim GW, Chung SH.

Biochem Pharmacol. 2013 May 1;85(9):1330-40. doi: 10.1016/j.bcp.2013.02.007. Epub 2013 Feb 19.

PMID:
23435355
16.

Acetic acid activates the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes.

Li X, Chen H, Guan Y, Li X, Lei L, Liu J, Yin L, Liu G, Wang Z.

PLoS One. 2013 Jul 4;8(7):e67880. doi: 10.1371/journal.pone.0067880. Print 2013.

17.

Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes.

Chen H, Zhang L, Li X, Li X, Sun G, Yuan X, Lei L, Liu J, Yin L, Deng Q, Wang J, Liu Z, Yang W, Wang Z, Zhang H, Liu G.

J Steroid Biochem Mol Biol. 2013 Nov;138:445-54. doi: 10.1016/j.jsbmb.2013.08.013. Epub 2013 Aug 30.

PMID:
23994141
18.

Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect.

Yan F, Wang Q, Xu C, Cao M, Zhou X, Wang T, Yu C, Jing F, Chen W, Gao L, Zhao J.

PLoS One. 2014 Jun 13;9(6):e99245. doi: 10.1371/journal.pone.0099245. eCollection 2014.

19.

Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD.

Zheng L, Lv GC, Sheng J, Yang YD.

J Gastroenterol Hepatol. 2010 Jan;25(1):156-63. doi: 10.1111/j.1440-1746.2009.05949.x. Epub 2009 Sep 25.

PMID:
19780876
20.

Effects of the new thiazolidine derivative LPSF/GQ-02 on hepatic lipid metabolism pathways in non-alcoholic fatty liver disease (NAFLD).

Araújo S, Soares E Silva A, Gomes F, Ribeiro E, Oliveira W, Oliveira A, Lima I, Lima MDC, Pitta I, Peixoto C.

Eur J Pharmacol. 2016 Oct 5;788:306-314. doi: 10.1016/j.ejphar.2016.06.043. Epub 2016 Jun 24.

PMID:
27349145

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