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Lack of association between let-7 binding site polymorphism rs712 and risk of nasopharyngeal carcinoma.

Pan XM, Jia J, Guo XM, Li ZH, Zhang Z, Qin HJ, Xu GH, Gao LB.

Fam Cancer. 2014 Mar;13(1):93-7. doi: 10.1007/s10689-013-9681-4.


A let-7 binding site polymorphism rs712 in the KRAS 3' UTR is associated with an increased risk of gastric cancer.

Li ZH, Pan XM, Han BW, Guo XM, Zhang Z, Jia J, Gao LB.

Tumour Biol. 2013 Oct;34(5):3159-63. doi: 10.1007/s13277-013-0885-x. Epub 2013 Jun 2.


Association of a let-7 KRAS rs712 polymorphism with the risk of breast cancer.

Huang X, Yang Y, Guo Y, Cao ZL, Cui ZW, Hu TC, Gao LB.

Genet Mol Res. 2015 Dec 14;14(4):16913-20. doi: 10.4238/2015.December.14.19.


A let-7 KRAS rs712 polymorphism increases colorectal cancer risk.

Pan XM, Sun RF, Li ZH, Guo XM, Zhang Z, Qin HJ, Xu GH, Gao LB.

Tumour Biol. 2014 Jan;35(1):831-5. doi: 10.1007/s13277-013-1114-3. Epub 2013 Aug 24.


Association between a functional polymorphism rs712 within let-7-binding site and risk of papillary thyroid cancer.

Jin H, Liang Y, Wang X, Zhu J, Sun R, Chen P, Nie X, Gao L, Zhang L.

Med Oncol. 2014 Oct;31(10):221. doi: 10.1007/s12032-014-0221-3. Epub 2014 Sep 9.


Association of rs712 polymorphism in Kras gene 3'-luntranslated region and cancer risk: a meta-analysis.

Zhao WH, Qu XF, Xing ZG, Zhao LQ, Qin L, Lv C.

J BUON. 2015 Jan-Feb;20(1):309-16. Review.


Significant association between Let-7-KRAS rs712 G > T polymorphism and cancer risk in the Chinese population: a meta-analysis.

Du XY, Hu YY, Xie C, Deng CY, Liu CY, Luo ZG, Niu YM, Shen M.

Oncotarget. 2017 Feb 21;8(8):13863-13871. doi: 10.18632/oncotarget.14672.


A variant in 3'-untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in patients with COPD.

Hu H, Zhang L, Teng G, Wu Y, Chen Y.

Int J Chron Obstruct Pulmon Dis. 2015 Aug 17;10:1641-9. doi: 10.2147/COPD.S83596. eCollection 2015.


An let-7 KRAS rs712 polymorphism increases hepatocellular carcinoma risk.

Xiong D, Song YP, Xiong W, Liang YD.

Genet Mol Res. 2015 Oct 30;14(4):14050-5. doi: 10.4238/2015.October.29.24.


A Functional Polymorphism in the Promoter of MiR-143/145 Is Associated With the Risk of Cervical Squamous Cell Carcinoma in Chinese Women: A Case-Control Study.

Liang Y, Sun R, Li L, Yuan F, Liang W, Wang L, Nie X, Chen P, Zhang L, Gao L.

Medicine (Baltimore). 2015 Aug;94(31):e1289. doi: 10.1097/MD.0000000000001289.


A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma.

Liu Y, Cai H, Liu J, Fan H, Wang Z, Wang Q, Shao M, Sun X, Diao J, Liu Y, Shi Y, Fan Q.

Biochem Biophys Res Commun. 2013 Mar 22;432(4):660-5. doi: 10.1016/j.bbrc.2013.02.024. Epub 2013 Feb 14.


A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk.

Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Muller RU, Straka E, Su L, Burki EA, Crowell RE, Patel R, Kulkarni T, Homer R, Zelterman D, Kidd KK, Zhu Y, Christiani DC, Belinsky SA, Slack FJ, Weidhaas JB.

Cancer Res. 2008 Oct 15;68(20):8535-40. doi: 10.1158/0008-5472.CAN-08-2129.


A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers.

Christensen BC, Moyer BJ, Avissar M, Ouellet LG, Plaza SL, McClean MD, Marsit CJ, Kelsey KT.

Carcinogenesis. 2009 Jun;30(6):1003-7. doi: 10.1093/carcin/bgp099. Epub 2009 Apr 20.


Association of miR-146a gene polymorphism with risk of nasopharyngeal carcinoma in the central-southern Chinese population.

Huang GL, Chen ML, Li YZ, Lu Y, Pu XX, He YX, Tang SY, Che H, Zou Y, Ding C, He Z.

J Hum Genet. 2014 Mar;59(3):141-4. doi: 10.1038/jhg.2013.135. Epub 2014 Jan 16.


Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases.

Kim M, Chen X, Chin LJ, Paranjape T, Speed WC, Kidd KK, Zhao H, Weidhaas JB, Slack FJ.

Cell Cycle. 2014;13(6):1030-40. doi: 10.4161/cc.27941. Epub 2014 Feb 3.


Cyclin D1 G870A polymorphism and risk of nasopharyngeal carcinoma: a case-control study and meta-analysis.

Liao D, Wu Y, Pu X, Chen H, Luo S, Li B, Ding C, Huang GL, He Z.

PLoS One. 2014 Nov 19;9(11):e113299. doi: 10.1371/journal.pone.0113299. eCollection 2014.


A functional polymorphism in MIR196A2 is associated with risk and progression of nasopharyngeal carcinoma in the Chinese population.

Li P, Yan H, Zhang H, Yu L, Wang Z, Zhai Y, Xia X, Zhang J, Zhang Y, Ma F, Huang W, Cai M, Cui Y, He F, Zhou G.

Genet Test Mol Biomarkers. 2014 Mar;18(3):149-55. doi: 10.1089/gtmb.2013.0400. Epub 2013 Dec 13.


Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab.

Kjersem JB, Ikdahl T, Guren T, Skovlund E, Sorbye H, Hamfjord J, Pfeiffer P, Glimelius B, Kersten C, Solvang H, Tveit KM, Kure EH.

BMC Cancer. 2012 Nov 20;12:534. doi: 10.1186/1471-2407-12-534.


Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).

Sha D, Lee AM, Shi Q, Alberts SR, Sargent DJ, Sinicrope FA, Diasio RB.

Clin Cancer Res. 2014 Jun 15;20(12):3319-27. doi: 10.1158/1078-0432.CCR-14-0069. Epub 2014 Apr 11.


Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.

Crowley EH, Arena S, Lamba S, Di Nicolantonio F, Bardelli A.

Hum Mutat. 2014 Feb;35(2):208-14. doi: 10.1002/humu.22487. Epub 2013 Dec 27.


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