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Items: 1 to 20 of 116


Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner.

Collette NM, Yee CS, Murugesh D, Sebastian A, Taher L, Gale NW, Economides AN, Harland RM, Loots GG.

Dev Biol. 2013 Nov 1;383(1):90-105. doi: 10.1016/j.ydbio.2013.08.015. Epub 2013 Aug 29.


Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb.

Nissim S, Allard P, Bandyopadhyay A, Harfe BD, Tabin CJ.

Dev Biol. 2007 Apr 1;304(1):9-21. Epub 2006 Dec 9.


Genetic evidence that SOST inhibits WNT signaling in the limb.

Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG.

Dev Biol. 2010 Jun 15;342(2):169-79. doi: 10.1016/j.ydbio.2010.03.021. Epub 2010 Mar 30.


Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3.

Bowers M, Eng L, Lao Z, Turnbull RK, Bao X, Riedel E, Mackem S, Joyner AL.

Dev Biol. 2012 Oct 1;370(1):110-24. doi: 10.1016/j.ydbio.2012.07.017. Epub 2012 Jul 25.


Wnt and BMP signaling cooperate with Hox in the control of Six2 expression in limb tendon precursor.

Yamamoto-Shiraishi Y, Kuroiwa A.

Dev Biol. 2013 May 15;377(2):363-74. doi: 10.1016/j.ydbio.2013.02.023. Epub 2013 Mar 13.


Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development.

Büscher D, Bosse B, Heymer J, Rüther U.

Mech Dev. 1997 Mar;62(2):175-82.


Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.

Quinn ME, Haaning A, Ware SM.

Hum Mol Genet. 2012 Apr 15;21(8):1888-96. doi: 10.1093/hmg/dds002. Epub 2012 Jan 10.


Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death.

Wong YL, Behringer RR, Kwan KM.

Dev Biol. 2012 Mar 1;363(1):247-57. doi: 10.1016/j.ydbio.2011.12.037. Epub 2012 Jan 3.


Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

te Welscher P, Zuniga A, Kuijper S, Drenth T, Goedemans HJ, Meijlink F, Zeller R.

Science. 2002 Oct 25;298(5594):827-30. Epub 2002 Sep 5.


Sp6 and Sp8 transcription factors control AER formation and dorsal-ventral patterning in limb development.

Haro E, Delgado I, Junco M, Yamada Y, Mansouri A, Oberg KC, Ros MA.

PLoS Genet. 2014 Aug 28;10(8):e1004468. doi: 10.1371/journal.pgen.1004468. eCollection 2014 Aug.


Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning.

Ahn Y, Sanderson BW, Klein OD, Krumlauf R.

Development. 2010 Oct;137(19):3221-31. doi: 10.1242/dev.054668. Epub 2010 Aug 19.


Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin.

Li J, Wang Q, Cui Y, Yang X, Li Y, Zhang X, Qiu M, Zhang Z, Zhang Z.

PLoS One. 2015 May 22;10(5):e0128006. doi: 10.1371/journal.pone.0128006. eCollection 2015.


Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.

McGlinn E, van Bueren KL, Fiorenza S, Mo R, Poh AM, Forrest A, Soares MB, Bonaldo Mde F, Grimmond S, Hui CC, Wainwright B, Wicking C.

Mech Dev. 2005 Nov;122(11):1218-33. Epub 2005 Aug 1.


Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.

Tu X, Rhee Y, Condon KW, Bivi N, Allen MR, Dwyer D, Stolina M, Turner CH, Robling AG, Plotkin LI, Bellido T.

Bone. 2012 Jan;50(1):209-17. doi: 10.1016/j.bone.2011.10.025. Epub 2011 Oct 30.


Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants.

Cao T, Wang C, Yang M, Wu C, Wang B.

Dev Biol. 2013 Jul 15;379(2):221-8. doi: 10.1016/j.ydbio.2013.04.025. Epub 2013 May 2.


Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.

Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C.

Nature. 2002 Aug 29;418(6901):979-83. Epub 2002 Aug 18.


Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites.

Borycki A, Brown AM, Emerson CP Jr.

Development. 2000 May;127(10):2075-87.


Role of Epiprofin, a zinc-finger transcription factor, in limb development.

Talamillo A, Delgado I, Nakamura T, de-Vega S, Yoshitomi Y, Unda F, Birchmeier W, Yamada Y, Ros MA.

Dev Biol. 2010 Jan 15;337(2):363-74. doi: 10.1016/j.ydbio.2009.11.007. Epub 2009 Nov 10.


Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells.

Collette NM, Yee CS, Hum NR, Murugesh DK, Christiansen BA, Xie L, Economides AN, Manilay JO, Robling AG, Loots GG.

Bone. 2016 Jul;88:20-30. doi: 10.1016/j.bone.2016.04.005. Epub 2016 Apr 19.

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