Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 108


Indometacin ameliorates high glucose-induced proliferation and invasion via modulation of e-cadherin in pancreatic cancer cells.

Han L, Peng B, Ma Q, Ma J, Li J, Li W, Duan W, Chen C, Liu J, Xu Q, Laporte K, Li Z, Wu E.

Curr Med Chem. 2013;20(33):4142-4152.


BMP2 accelerates the motility and invasiveness of gastric cancer cells via activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway.

Kang MH, Kim JS, Seo JE, Oh SC, Yoo YA.

Exp Cell Res. 2010 Jan 1;316(1):24-37. doi: 10.1016/j.yexcr.2009.10.010. Epub 2009 Oct 14.


Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3β, Snail1, and β-catenin in renal proximal tubule cells.

Lee YJ, Han HJ.

Am J Physiol Renal Physiol. 2010 May;298(5):F1263-75. doi: 10.1152/ajprenal.00475.2009. Epub 2009 Dec 16.


ERalpha signaling through slug regulates E-cadherin and EMT.

Ye Y, Xiao Y, Wang W, Yearsley K, Gao JX, Shetuni B, Barsky SH.

Oncogene. 2010 Mar 11;29(10):1451-62. doi: 10.1038/onc.2009.433. Epub 2010 Jan 18.


Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.

Xu Z, Zhang Y, Jiang J, Yang Y, Shi R, Hao B, Zhang Z, Huang Z, Kim JW, Zhang G.

BMC Cancer. 2010 Apr 27;10:161. doi: 10.1186/1471-2407-10-161.


Elevated Expression of Zinc Finger Protein 703 Promotes Cell Proliferation and Metastasis through PI3K/AKT/GSK-3β Signalling in Oral Squamous Cell Carcinoma.

Wang H, Deng X, Zhang J, Ou Z, Mai J, Ding S, Huo S.

Cell Physiol Biochem. 2017;44(3):920-934. doi: 10.1159/000485360. Epub 2017 Nov 24.


TNF-α induces epithelial-mesenchymal transition of renal cell carcinoma cells via a GSK3β-dependent mechanism.

Ho MY, Tang SJ, Chuang MJ, Cha TL, Li JY, Sun GH, Sun KH.

Mol Cancer Res. 2012 Aug;10(8):1109-19. doi: 10.1158/1541-7786.MCR-12-0160. Epub 2012 Jun 15.


PI3K/Akt-dependent phosphorylation of GSK3β and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration.

Liu J, Zhang Y, Xu R, Du J, Hu Z, Yang L, Chen Y, Zhu Y, Gu L.

Cell Signal. 2013 Feb;25(2):447-56. doi: 10.1016/j.cellsig.2012.10.012. Epub 2012 Oct 31.


Lipopolysaccharide induces lung fibroblast proliferation through Toll-like receptor 4 signaling and the phosphoinositide3-kinase-Akt pathway.

He Z, Gao Y, Deng Y, Li W, Chen Y, Xing S, Zhao X, Ding J, Wang X.

PLoS One. 2012;7(4):e35926. doi: 10.1371/journal.pone.0035926. Epub 2012 Apr 26.


Soluble epoxide hydrolase inhibition ameliorates proteinuria-induced epithelial-mesenchymal transition by regulating the PI3K-Akt-GSK-3β signaling pathway.

Liang Y, Jing Z, Deng H, Li Z, Zhuang Z, Wang S, Wang Y.

Biochem Biophys Res Commun. 2015 Jul 17-24;463(1-2):70-5. doi: 10.1016/j.bbrc.2015.05.020. Epub 2015 May 15.


The PI3K/Akt/mTOR signaling pathway mediates insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells.

Lau MT, Leung PC.

Cancer Lett. 2012 Dec 30;326(2):191-8. doi: 10.1016/j.canlet.2012.08.016. Epub 2012 Aug 21.


Inhibition of IGF-1 signaling by genistein: modulation of E-cadherin expression and downregulation of β-catenin signaling in hormone refractory PC-3 prostate cancer cells.

Lee J, Ju J, Park S, Hong SJ, Yoon S.

Nutr Cancer. 2012;64(1):153-62. doi: 10.1080/01635581.2012.630161. Epub 2011 Nov 18.


Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-κB pathway.

Li W, Ma J, Ma Q, Li B, Han L, Liu J, Xu Q, Duan W, Yu S, Wang F, Wu E.

Curr Med Chem. 2013;20(33):4185-4194.


miR-208-induced epithelial to mesenchymal transition of pancreatic cancer cells promotes cell metastasis and invasion.

Liu A, Shao C, Jin G, Liu R, Hao J, Song B, Ouyang L, Hu X.

Cell Biochem Biophys. 2014 Jun;69(2):341-6. doi: 10.1007/s12013-013-9805-3.


CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.

Zang M, Zhang B, Zhang Y, Li J, Su L, Zhu Z, Gu Q, Liu B, Yan M.

PLoS One. 2014 Nov 14;9(11):e112908. doi: 10.1371/journal.pone.0112908. eCollection 2014.


GSK-3β and vitamin D receptor are involved in β-catenin and snail signaling in high glucose-induced epithelial-mesenchymal transition of mouse podocytes.

Guo J, Xia N, Yang L, Zhou S, Zhang Q, Qiao Y, Liu Z.

Cell Physiol Biochem. 2014;33(4):1087-96. doi: 10.1159/000358678. Epub 2014 Apr 9.


Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion.

Shukla S, Maclennan GT, Hartman DJ, Fu P, Resnick MI, Gupta S.

Int J Cancer. 2007 Oct 1;121(7):1424-32.


Embelin-Induced Apoptosis of Human Prostate Cancer Cells Is Mediated through Modulation of Akt and β-Catenin Signaling.

Park N, Baek HS, Chun YJ.

PLoS One. 2015 Aug 7;10(8):e0134760. doi: 10.1371/journal.pone.0134760. eCollection 2015.


[High D-glucose alters PI3K and Akt signaling and leads to endothelial cell migration, proliferation and angiogenesis dysfunction].

Yu P, Yu DM, Qi JC, Wang J, Zhang QM, Zhang JY, Tang YZ, Xing QL, Li MZ.

Zhonghua Yi Xue Za Zhi. 2006 Dec 26;86(48):3425-30. Chinese.


Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein.

Sugita H, Kaneki M, Furuhashi S, Hirota M, Takamori H, Baba H.

Mol Cancer Res. 2010 Aug;8(8):1152-63. doi: 10.1158/1541-7786.MCR-09-0472. Epub 2010 Jul 27.

Supplemental Content

Support Center