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Items: 1 to 20 of 88

1.

Measuring interference of drug-like molecules with the respiratory chain: toward the early identification of mitochondrial uncouplers in lead finding.

Stock U, Matter H, Diekert K, Dörner W, Dröse S, Licher T.

Assay Drug Dev Technol. 2013 Sep;11(7):408-22. doi: 10.1089/adt.2012.463. Epub 2013 Aug 30.

2.

High resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system.

Hall A, Larsen AK, Parhamifar L, Meyle KD, Wu LP, Moghimi SM.

Biochim Biophys Acta. 2013 Oct;1827(10):1213-25. doi: 10.1016/j.bbabio.2013.07.001. Epub 2013 Jul 11.

3.

Structures of mitochondrial oxidative phosphorylation supercomplexes and mechanisms for their stabilisation.

Chaban Y, Boekema EJ, Dudkina NV.

Biochim Biophys Acta. 2014 Apr;1837(4):418-26. doi: 10.1016/j.bbabio.2013.10.004. Epub 2013 Oct 30. Review.

4.

Electrophysiology of respiratory chain complexes and the ADP-ATP exchanger in native mitochondrial membranes.

Watzke N, Diekert K, Obrdlik P.

Biochemistry. 2010 Dec 7;49(48):10308-18. doi: 10.1021/bi1011755. Epub 2010 Nov 11.

PMID:
20958090
5.

Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure.

Rhein V, Giese M, Baysang G, Meier F, Rao S, Schulz KL, Hamburger M, Eckert A.

PLoS One. 2010 Aug 24;5(8):e12359. doi: 10.1371/journal.pone.0012359.

7.

The higher level of organization of the oxidative phosphorylation system: mitochondrial supercomplexes.

Dudkina NV, Sunderhaus S, Boekema EJ, Braun HP.

J Bioenerg Biomembr. 2008 Oct;40(5):419-24. doi: 10.1007/s10863-008-9167-5. Epub 2008 Oct 7. Review.

8.

Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC complexes.

Vineetha VP, Soumya RS, Raghu KG.

Eur J Pharmacol. 2015 May 5;754:162-72. doi: 10.1016/j.ejphar.2015.02.036. Epub 2015 Mar 3.

PMID:
25746422
9.

Development of an assay for Complex I/Complex III of the respiratory chain using solid supported membranes and its application in mitochondrial toxicity screening in drug discovery.

Preissl S, Bick I, Obrdlik P, Diekert K, Gul S, Gribbon P.

Assay Drug Dev Technol. 2011 Apr;9(2):147-56. doi: 10.1089/adt.2010.0320. Epub 2010 Dec 6.

PMID:
21133681
10.

Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury.

Shaik ZP, Fifer EK, Nowak G.

Am J Physiol Renal Physiol. 2008 Feb;294(2):F423-32. Epub 2007 Dec 12.

11.

Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction.

Stanyer L, Jorgensen W, Hori O, Clark JB, Heales SJ.

Neurochem Int. 2008 Sep;53(3-4):95-101. doi: 10.1016/j.neuint.2008.06.004. Epub 2008 Jun 12.

PMID:
18598728
12.

Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol.

Jaña F, Faini F, Lapier M, Pavani M, Kemmerling U, Morello A, Maya JD, Jara J, Parra E, Ferreira J.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64. doi: 10.1016/j.taap.2013.06.005. Epub 2013 Jun 15.

PMID:
23777606
13.

Toxicity of copper on isolated liver mitochondria: impairment at complexes I, II, and IV leads to increased ROS production.

Hosseini MJ, Shaki F, Ghazi-Khansari M, Pourahmad J.

Cell Biochem Biophys. 2014 Sep;70(1):367-81. doi: 10.1007/s12013-014-9922-7.

PMID:
24691927
14.

Functional expression of oxidative phosphorylation proteins in the rod outer segment disc.

Panfoli I, Calzia D, Bruschi M, Oneto M, Bianchini P, Ravera S, Petretto A, Diaspro A, Candiano G.

Cell Biochem Funct. 2013 Aug;31(6):532-8. doi: 10.1002/cbf.2943. Epub 2013 Jan 16.

PMID:
23322616
15.

Nitric oxide compounds have different effects profiles on human articular chondrocyte metabolism.

de Andrés MC, Maneiro E, Martín MA, Arenas J, Blanco FJ.

Arthritis Res Ther. 2013;15(5):R115.

16.

Lipophilic triphenylphosphonium cations inhibit mitochondrial electron transport chain and induce mitochondrial proton leak.

Trnka J, Elkalaf M, Anděl M.

PLoS One. 2015 Apr 30;10(4):e0121837. doi: 10.1371/journal.pone.0121837. eCollection 2015.

17.

Biochemical analyses of the electron transport chain complexes by spectrophotometry.

Frazier AE, Thorburn DR.

Methods Mol Biol. 2012;837:49-62. doi: 10.1007/978-1-61779-504-6_4.

PMID:
22215540
18.

Structure and function of mitochondrial supercomplexes.

Dudkina NV, Kouril R, Peters K, Braun HP, Boekema EJ.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):664-70. doi: 10.1016/j.bbabio.2009.12.013. Epub 2009 Dec 28. Review.

19.

Mitochondrial medicine--molecular pathology of defective oxidative phosphorylation.

Fosslien E.

Ann Clin Lab Sci. 2001 Jan;31(1):25-67. Review.

PMID:
11314862
20.

A miniaturized homogenous assay of mitochondrial membrane potential.

Vongs A, Solly KJ, Kiss L, Macneil DJ, Rosenblum CI.

Assay Drug Dev Technol. 2011 Aug;9(4):373-81. doi: 10.1089/adt.2010.0301. Epub 2011 Feb 6.

PMID:
21294696

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