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Items: 1 to 20 of 87

1.

Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5.

Duguay BA, Smiley JR.

J Virol. 2013 Nov;87(21):11787-97. doi: 10.1128/JVI.02306-13. Epub 2013 Aug 28.

2.

Elimination of mitochondrial DNA is not required for herpes simplex virus 1 replication.

Duguay BA, Saffran HA, Ponomarev A, Duley SA, Eaton HE, Smiley JR.

J Virol. 2014 Mar;88(5):2967-76. doi: 10.1128/JVI.03129-13. Epub 2013 Dec 26.

3.

Herpes simplex virus UL12.5 targets mitochondria through a mitochondrial localization sequence proximal to the N terminus.

Corcoran JA, Saffran HA, Duguay BA, Smiley JR.

J Virol. 2009 Mar;83(6):2601-10. doi: 10.1128/JVI.02087-08. Epub 2009 Jan 7.

4.

The Exonuclease Activity of Herpes Simplex Virus 1 UL12 Is Required for Production of Viral DNA That Can Be Packaged To Produce Infectious Virus.

Grady LM, Szczepaniak R, Murelli RP, Masaoka T, Le Grice SFJ, Wright DL, Weller SK.

J Virol. 2017 Nov 14;91(23). pii: e01380-17. doi: 10.1128/JVI.01380-17. Print 2017 Dec 1.

5.

Herpes simplex virus eliminates host mitochondrial DNA.

Saffran HA, Pare JM, Corcoran JA, Weller SK, Smiley JR.

EMBO Rep. 2007 Feb;8(2):188-93. Epub 2006 Dec 22.

6.

Role of the nuclease activities encoded by herpes simplex virus 1 UL12 in viral replication and neurovirulence.

Fujii H, Mugitani M, Koyanagi N, Liu Z, Tsuda S, Arii J, Kato A, Kawaguchi Y.

J Virol. 2014 Feb;88(4):2359-64. doi: 10.1128/JVI.03621-13. Epub 2013 Dec 11.

7.

Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complex.

Balasubramanian N, Bai P, Buchek G, Korza G, Weller SK.

J Virol. 2010 Dec;84(24):12504-14. doi: 10.1128/JVI.01506-10. Epub 2010 Oct 13.

8.

The generation of oxidative stress-induced rearrangements in Saccharomyces cerevisiae mtDNA is dependent on the Nuc1 (EndoG/ExoG) nuclease and is enhanced by inactivation of the MRX complex.

Dzierzbicki P, Kaniak-Golik A, Malc E, Mieczkowski P, Ciesla Z.

Mutat Res. 2012 Dec;740(1-2):21-33. doi: 10.1016/j.mrfmmm.2012.12.004. Epub 2012 Dec 28.

PMID:
23276591
9.

The UL12 protein of herpes simplex virus 1 is regulated by tyrosine phosphorylation.

Fujii H, Kato A, Mugitani M, Kashima Y, Oyama M, Kozuka-Hata H, Arii J, Kawaguchi Y.

J Virol. 2014 Sep;88(18):10624-34. doi: 10.1128/JVI.01634-14. Epub 2014 Jul 2.

10.

EXOG, a novel paralog of Endonuclease G in higher eukaryotes.

Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G.

Nucleic Acids Res. 2008 Mar;36(4):1369-79. doi: 10.1093/nar/gkm1169. Epub 2008 Jan 10.

11.

The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism.

Schumacher AJ, Mohni KN, Kan Y, Hendrickson EA, Stark JM, Weller SK.

PLoS Pathog. 2012;8(8):e1002862. doi: 10.1371/journal.ppat.1002862. Epub 2012 Aug 9.

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15.

Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans.

Kieper J, Lauber C, Gimadutdinow O, UrbaƄska A, Cymerman I, Ghosh M, Szczesny B, Meiss G.

Protein Expr Purif. 2010 Sep;73(1):99-106. doi: 10.1016/j.pep.2010.04.001. Epub 2010 Apr 9.

PMID:
20382228
17.

Mammalian mitochondrial endonuclease G. Digestion of R-loops and localization in intermembrane space.

Ohsato T, Ishihara N, Muta T, Umeda S, Ikeda S, Mihara K, Hamasaki N, Kang D.

Eur J Biochem. 2002 Dec;269(23):5765-70.

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