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Items: 1 to 20 of 292

1.

The herbal compound cryptotanshinone restores sensitivity in cancer cells that are resistant to the tumor necrosis factor-related apoptosis-inducing ligand.

Tse AK, Chow KY, Cao HH, Cheng CY, Kwan HY, Yu H, Zhu GY, Wu YC, Fong WF, Yu ZL.

J Biol Chem. 2013 Oct 11;288(41):29923-33. doi: 10.1074/jbc.M113.483909. Epub 2013 Aug 28.

3.

Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.

Sung B, Ravindran J, Prasad S, Pandey MK, Aggarwal BB.

J Biol Chem. 2010 Nov 12;285(46):35418-27. doi: 10.1074/jbc.M110.172767. Epub 2010 Sep 13. Retraction in: Sung B, Ravindran J, Prasad S, Pandey MK, Aggarwal BB. J Biol Chem. 2016 Aug 5;291(32):16923.

5.

Indomethacin sensitizes TRAIL-resistant melanoma cells to TRAIL-induced apoptosis through ROS-mediated upregulation of death receptor 5 and downregulation of survivin.

Tse AK, Cao HH, Cheng CY, Kwan HY, Yu H, Fong WF, Yu ZL.

J Invest Dermatol. 2014 May;134(5):1397-1407. doi: 10.1038/jid.2013.471. Epub 2013 Nov 8.

6.

ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.

Prasad S, Yadav VR, Ravindran J, Aggarwal BB.

Cancer Res. 2011 Jan 15;71(2):538-49. doi: 10.1158/0008-5472.CAN-10-3121. Epub 2010 Dec 2.

7.

Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.

Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF.

Chem Res Toxicol. 2015 Aug 17;28(8):1574-83. doi: 10.1021/acs.chemrestox.5b00150. Epub 2015 Jul 31.

PMID:
26203587
8.

Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation.

Chen L, Meng Y, Sun Q, Zhang Z, Guo X, Sheng X, Tai G, Cheng H, Zhou Y.

Cell Death Dis. 2016 Aug 11;7(8):e2334. doi: 10.1038/cddis.2016.234.

9.

Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner.

Moon DO, Asami Y, Long H, Jang JH, Bae EY, Kim BY, Choi YH, Kang CH, Ahn JS, Kim GY.

Toxicol In Vitro. 2013 Feb;27(1):257-63. doi: 10.1016/j.tiv.2012.09.001. Epub 2012 Sep 12.

PMID:
22982206
10.
11.

Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.

Sung B, Prasad S, Ravindran J, Yadav VR, Aggarwal BB.

Free Radic Biol Med. 2012 Nov 15;53(10):1977-87. doi: 10.1016/j.freeradbiomed.2012.08.012. Epub 2012 Aug 15.

12.

Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.

Taniguchi H, Yoshida T, Horinaka M, Yasuda T, Goda AE, Konishi M, Wakada M, Kataoka K, Yoshikawa T, Sakai T.

Cancer Res. 2008 Nov 1;68(21):8918-27. doi: 10.1158/0008-5472.CAN-08-1120.

13.

Cyclopamine sensitizes TRAIL-resistant gastric cancer cells to TRAIL-induced apoptosis via endoplasmic reticulum stress-mediated increase of death receptor 5 and survivin degradation.

Na YJ, Lee DH, Kim JL, Kim BR, Park SH, Jo MJ, Jeong S, Kim HJ, Lee SY, Jeong YA, Oh SC.

Int J Biochem Cell Biol. 2017 Aug;89:147-156. doi: 10.1016/j.biocel.2017.06.010. Epub 2017 Jun 15.

PMID:
28624529
14.

The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells.

Fujiwara J, Sowa Y, Horinaka M, Koyama M, Wakada M, Miki T, Sakai T.

Int J Oncol. 2012 May;40(5):1483-91. doi: 10.3892/ijo.2012.1353. Epub 2012 Feb 2. Erratum in: Int J Oncol. 2016 Feb;48(2):854.

PMID:
22328338
15.

Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.

Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T.

Mol Cancer Res. 2008 Dec;6(12):1852-60. doi: 10.1158/1541-7786.MCR-08-0012.

16.

Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.

Kim YH, Jung EM, Lee TJ, Kim SH, Choi YH, Park JW, Park JW, Choi KS, Kwon TK.

Free Radic Biol Med. 2008 Mar 15;44(6):1055-68. doi: 10.1016/j.freeradbiomed.2007.12.001. Epub 2007 Dec 8.

PMID:
18164688
17.

Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation.

Kim IY, Kang YJ, Yoon MJ, Kim EH, Kim SU, Kwon TK, Kim IA, Choi KS.

Neuro Oncol. 2011 Mar;13(3):267-79. doi: 10.1093/neuonc/noq195. Epub 2011 Feb 3.

18.
19.

Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway.

Kim JH, Park B, Gupta SC, Kannappan R, Sung B, Aggarwal BB.

Antioxid Redox Signal. 2012 Mar 1;16(5):413-27. doi: 10.1089/ars.2011.3982. Epub 2011 Dec 15. Erratum in: Antioxid Redox Signal. 2013 Jan 10;18(2):219-20.

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