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Items: 1 to 20 of 86

1.

Neuregulin1beta1 antagonizes apoptosis via ErbB4-dependent activation of PI3-kinase/Akt in APP/PS1 transgenic mice.

Cui W, Tao J, Wang Z, Ren M, Zhang Y, Sun Y, Peng Y, Li R.

Neurochem Res. 2013 Nov;38(11):2237-46. doi: 10.1007/s11064-013-1131-z. Epub 2013 Aug 28.

PMID:
23982319
2.

Neuregulin1β1 protects oligodendrocyte progenitor cells from oxygen glucose deprivation injury induced apoptosis via ErbB4-dependent activation of PI3-kinase/Akt.

Xu C, Lv L, Zheng G, Li B, Gao L, Sun Y.

Brain Res. 2012 Jul 27;1467:104-12. doi: 10.1016/j.brainres.2012.05.044. Epub 2012 May 29.

PMID:
22659027
3.

Neuregulin-1 protects against neurotoxicities induced by Swedish amyloid precursor protein via the ErbB4 receptor.

Woo RS, Lee JH, Kim HS, Baek CH, Song DY, Suh YH, Baik TK.

Neuroscience. 2012 Jan 27;202:413-23. doi: 10.1016/j.neuroscience.2011.11.026. Epub 2011 Dec 13.

PMID:
22186019
4.

β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice.

Wei G, Chen YB, Chen DF, Lai XP, Liu DH, Deng RD, Zhou JH, Zhang SX, Li YW, Lii H, Liu LF, Wang Q, Nie H.

J Alzheimers Dis. 2013;33(3):863-80. doi: 10.3233/JAD-2012-120865.

PMID:
23064259
5.

Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/Bcl(XL)-regulated mitochondrial apoptotic pathway.

Zeng KW, Wang XM, Ko H, Kwon HC, Cha JW, Yang HO.

Eur J Pharmacol. 2011 Dec 15;672(1-3):45-55. doi: 10.1016/j.ejphar.2011.09.177. Epub 2011 Sep 29.

PMID:
21978835
6.

Neuregulin-1 exerts protective effects against neurotoxicities induced by C-terminal fragments of APP via ErbB4 receptor.

Ryu J, Yu HN, Cho H, Kim HS, Baik TK, Lee SJ, Woo RS.

J Pharmacol Sci. 2012;119(1):73-81.

7.

Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice.

Wang C, Zhang X, Teng Z, Zhang T, Li Y.

Eur J Pharmacol. 2014 Oct 5;740:312-20. doi: 10.1016/j.ejphar.2014.06.051. Epub 2014 Jul 17.

PMID:
25041840
8.

1,5-dicaffeoylquinic acid protects primary neurons from amyloid β 1-42-induced apoptosis via PI3K/Akt signaling pathway.

Xiao HB, Cao X, Wang L, Run XQ, Su Y, Tian C, Sun SG, Liang ZH.

Chin Med J (Engl). 2011 Sep;124(17):2628-35.

PMID:
22040415
9.

Upregulation of AKT attenuates amyloid-β-induced cell apoptosis.

Yin G, Li LY, Qu M, Luo HB, Wang JZ, Zhou XW.

J Alzheimers Dis. 2011;25(2):337-45. doi: 10.3233/JAD-2011-110104.

PMID:
21422525
10.

Valproic acid attenuates neuronal loss in the brain of APP/PS1 double transgenic Alzheimer's disease mice model.

Long Z, Zheng M, Zhao L, Xie P, Song C, Chu Y, Song W, He G.

Curr Alzheimer Res. 2013 Mar;10(3):261-9.

PMID:
23036022
11.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

12.

The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.

Li N, Liu GT.

Acta Pharmacol Sin. 2010 Mar;31(3):265-72. doi: 10.1038/aps.2010.3. Epub 2010 Feb 15.

13.

Puerarin protects differentiated PC12 cells from H₂O₂-induced apoptosis through the PI3K/Akt signalling pathway.

Zhang Q, Huang WD, Lv XY, Yang YM.

Cell Biol Int. 2012 May 1;36(5):419-26. doi: 10.1042/CBI20100900.

PMID:
22126839
14.

PI3K/Akt signaling pathway is required for neuroprotection of thalidomide on hypoxic-ischemic cortical neurons in vitro.

Zhang L, Qu Y, Tang J, Chen D, Fu X, Mao M, Mu D.

Brain Res. 2010 Oct 21;1357:157-65. doi: 10.1016/j.brainres.2010.08.007. Epub 2010 Aug 10.

PMID:
20705061
15.

Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt.

Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, Sawyer DB.

J Mol Cell Cardiol. 2003 Dec;35(12):1473-9.

PMID:
14654373
16.

Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region.

Zhong Z, Wang Y, Guo H, Sagare A, Fernández JA, Bell RD, Barrett TM, Griffin JH, Freeman RS, Zlokovic BV.

J Neurosci. 2010 Nov 17;30(46):15521-34. doi: 10.1523/JNEUROSCI.4437-10.2010.

17.

Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells.

Shi C, Wu F, Yew DT, Xu J, Zhu Y.

Apoptosis. 2010 Jun;15(6):715-27. doi: 10.1007/s10495-010-0492-x.

PMID:
20333467
18.

The protective effect of sonic hedgehog is mediated by the phosphoinositide [corrected] 3-kinase/AKT/Bcl-2 pathway in cultured rat astrocytes under oxidative stress.

Xia YP, Dai RL, Li YN, Mao L, Xue YM, He QW, Huang M, Huang Y, Mei YW, Hu B.

Neuroscience. 2012 May 3;209:1-11. doi: 10.1016/j.neuroscience.2012.02.019. Epub 2012 Feb 21. Erratum in: Neuroscience. 2012 Jun 28;213:201.

PMID:
22402346
19.

PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease.

O' Neill C.

Exp Gerontol. 2013 Jul;48(7):647-53. doi: 10.1016/j.exger.2013.02.025. Epub 2013 Mar 5. Review.

PMID:
23470275
20.

Akt-mediated survival of oligodendrocytes induced by neuregulins.

Flores AI, Mallon BS, Matsui T, Ogawa W, Rosenzweig A, Okamoto T, Macklin WB.

J Neurosci. 2000 Oct 15;20(20):7622-30.

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