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Items: 1 to 20 of 308

1.

NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke.

Wang Z, Wei X, Liu K, Zhang X, Yang F, Zhang H, He Y, Zhu T, Li F, Shi W, Zhang Y, Xu H, Liu J, Yi F.

Free Radic Biol Med. 2013 Dec;65:942-51. doi: 10.1016/j.freeradbiomed.2013.08.166. Epub 2013 Aug 24.

PMID:
23982049
2.

NOD2 is involved in the inflammatory response after cerebral ischemia-reperfusion injury and triggers NADPH oxidase 2-derived reactive oxygen species.

Liu H, Wei X, Kong L, Liu X, Cheng L, Yan S, Zhang X, Chen L.

Int J Biol Sci. 2015 Mar 25;11(5):525-35. doi: 10.7150/ijbs.10927. eCollection 2015.

3.
4.

NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.

Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F.

J Cereb Blood Flow Metab. 2014 Apr;34(4):660-7. doi: 10.1038/jcbfm.2013.242. Epub 2014 Jan 15.

5.

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice.

Jackman KA, Miller AA, De Silva TM, Crack PJ, Drummond GR, Sobey CG.

Br J Pharmacol. 2009 Feb;156(4):680-8. doi: 10.1111/j.1476-5381.2008.00073.x. Epub 2009 Jan 23.

6.

Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence.

Zheng JL, Li GZ, Chen SZ, Wang JJ, Olson JE, Xia HJ, Lazartigues E, Zhu YL, Chen YF.

CNS Neurosci Ther. 2014 May;20(5):452-9. doi: 10.1111/cns.12233. Epub 2014 Mar 2.

7.

Activation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of reactive oxygen species and calpain activation.

Guemez-Gamboa A, Estrada-Sánchez AM, Montiel T, Páramo B, Massieu L, Morán J.

J Neuropathol Exp Neurol. 2011 Nov;70(11):1020-35. doi: 10.1097/NEN.0b013e3182358e4e.

PMID:
22002428
8.

Release of mitochondrial apoptogenic factors and cell death are mediated by CK2 and NADPH oxidase.

Kim GS, Jung JE, Narasimhan P, Sakata H, Yoshioka H, Song YS, Okami N, Chan PH.

J Cereb Blood Flow Metab. 2012 Apr;32(4):720-30. doi: 10.1038/jcbfm.2011.176. Epub 2011 Dec 7.

9.

NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.

Li N, Li B, Brun T, Deffert-Delbouille C, Mahiout Z, Daali Y, Ma XJ, Krause KH, Maechler P.

Diabetes. 2012 Nov;61(11):2842-50. doi: 10.2337/db12-0009. Epub 2012 Aug 28.

10.

Alterations in the time course of expression of the Nox family in the brain in a rat experimental cerebral ischemia and reperfusion model: effects of melatonin.

Li H, Wang Y, Feng D, Liu Y, Xu M, Gao A, Tian F, Zhang L, Cui Y, Wang Z, Chen G.

J Pineal Res. 2014 Aug;57(1):110-9. doi: 10.1111/jpi.12148. Epub 2014 Jun 16.

PMID:
24867613
11.

Calpain activation induced by glucose deprivation is mediated by oxidative stress and contributes to neuronal damage.

Páramo B, Montiel T, Hernández-Espinosa DR, Rivera-Martínez M, Morán J, Massieu L.

Int J Biochem Cell Biol. 2013 Nov;45(11):2596-604. doi: 10.1016/j.biocel.2013.08.013. Epub 2013 Aug 29.

PMID:
23994487
12.

Inhibition of gp91(phox) contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia.

Tang X, Liu KJ, Ramu J, Chen Q, Li T, Liu W.

Brain Res. 2010 Aug 12;1348:174-80. doi: 10.1016/j.brainres.2010.05.082. Epub 2010 Jun 11.

13.

Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke.

De Silva TM, Brait VH, Drummond GR, Sobey CG, Miller AA.

PLoS One. 2011;6(12):e28393. doi: 10.1371/journal.pone.0028393. Epub 2011 Dec 2.

14.

Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide.

Brait VH, Jackman KA, Walduck AK, Selemidis S, Diep H, Mast AE, Guida E, Broughton BR, Drummond GR, Sobey CG.

J Cereb Blood Flow Metab. 2010 Jul;30(7):1306-17. doi: 10.1038/jcbfm.2010.14. Epub 2010 Feb 10.

15.

Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini.

Falkowski MA, Thomas DD, Groblewski GE.

J Biol Chem. 2010 Nov 12;285(46):35558-66. doi: 10.1074/jbc.M110.146597. Epub 2010 Sep 9.

16.

Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury.

Braunersreuther V, Montecucco F, Asrih M, Pelli G, Galan K, Frias M, Burger F, Quinderé AL, Montessuit C, Krause KH, Mach F, Jaquet V.

J Mol Cell Cardiol. 2013 Nov;64:99-107. doi: 10.1016/j.yjmcc.2013.09.007. Epub 2013 Sep 16. Erratum in: J Mol Cell Cardiol. 2014 Jan;66:189. Ashri, Mohammed [corrected to Asrih, Mohamed].

PMID:
24051369
17.

Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain.

Park L, Anrather J, Girouard H, Zhou P, Iadecola C.

J Cereb Blood Flow Metab. 2007 Dec;27(12):1908-18. Epub 2007 Apr 11.

PMID:
17429347
18.

Deficiency in the voltage-gated proton channel Hv1 increases M2 polarization of microglia and attenuates brain damage from photothrombotic ischemic stroke.

Tian DS, Li CY, Qin C, Murugan M, Wu LJ, Liu JL.

J Neurochem. 2016 Oct;139(1):96-105. doi: 10.1111/jnc.13751. Epub 2016 Sep 9.

19.

Genetic deficiency of β2-containing nicotinic receptors attenuates brain injury in ischemic stroke.

Liu Q, Tang Z, Gan Y, Wu W, Kousari A, La Cava A, Shi FD.

Neuroscience. 2014 Jan 3;256:170-7. doi: 10.1016/j.neuroscience.2013.10.049. Epub 2013 Oct 30.

PMID:
24184117
20.

Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia.

Urao N, Inomata H, Razvi M, Kim HW, Wary K, McKinney R, Fukai T, Ushio-Fukai M.

Circ Res. 2008 Jul 18;103(2):212-20. doi: 10.1161/CIRCRESAHA.108.176230. Epub 2008 Jun 26.

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