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Items: 1 to 20 of 98

1.

Formal synthesis of (+)-madindoline A, a potent IL-6 inhibitor, utilizing enzymatic discrimination of quaternary carbon.

Shimizu K, Tomita M, Fuhshuku K, Sugai T, Shoji M.

Nat Prod Commun. 2013 Jul;8(7):897-901.

PMID:
23980418
2.

Short total synthesis of (+)-madindolines A and B.

Hirose T, Sunazuka T, Shirahata T, Yamamoto D, Harigaya Y, Kuwajima I, Omura S.

Org Lett. 2002 Feb 21;4(4):501-3.

PMID:
11843576
3.

Design, synthesis, and biological activities of madindoline analogues.

Yamamoto D, Sunazuka T, Hirose T, Kojima N, Kaji E, Omura S.

Bioorg Med Chem Lett. 2006 May 15;16(10):2807-11.

PMID:
16481161
4.

Synthesis of (+)-madindoline A and (+)-madindoline B.

Wan L, Tius MA.

Org Lett. 2007 Feb 15;9(4):647-50.

5.

Synthesis of (+/-)-madindolines and chemical models. Studies of chemical reactivity.

McComas CC, Perales JB, Van Vranken DL.

Org Lett. 2002 Jul 11;4(14):2337-40.

PMID:
12098241
6.

Madindoline, a novel inhibitor of IL-6 activity from Streptomyces sp. K93-0711. I. Taxonomy, fermentation, isolation and biological activities.

Hayashi M, Kim YP, Takamatsu S, Enomoto A, Shinose M, Takahashi Y, Tanaka H, Komiyama K, Omura S.

J Antibiot (Tokyo). 1996 Nov;49(11):1091-5.

7.
8.

Structure-activity relationship study of a series of novel oxazolidinone derivatives as IL-6 signaling blockers.

Singh S, Gajulapati V, Gajulapati K, Goo JI, Park YH, Jung HY, Lee SY, Choi JH, Kim YK, Lee K, Heo TH, Choi Y.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1282-6. doi: 10.1016/j.bmcl.2016.01.016.

PMID:
26810262
9.

Total syntheses of zaragozic acids A and C by a carbonyl ylide cycloaddition strategy.

Hirata Y, Nakamura S, Watanabe N, Kataoka O, Kurosaki T, Anada M, Kitagaki S, Shiro M, Hashimoto S.

Chemistry. 2006 Dec 4;12(35):8898-925.

PMID:
17106907
10.

Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130.

Hayashi M, Rho MC, Enomoto A, Fukami A, Kim YP, Kikuchi Y, Sunazuka T, Hirose T, Komiyama K, Omura S.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14728-33.

11.
12.

Tungsten-catalyzed heterocycloisomerization approach to 4,5-dihydro-benzo[b]furans and -indoles.

Fisher EL, Wilkerson-Hill SM, Sarpong R.

J Am Chem Soc. 2012 Jun 20;134(24):9946-9. doi: 10.1021/ja3045647.

PMID:
22663199
13.

Formal total synthesis of (+)-salicylihalamides A and B: a combined chiral pool and RCM strategy.

Yang K, Blackman B, Diederich W, Flaherty PT, Mossman CJ, Roy S, Ahn YM, Georg GI.

J Org Chem. 2003 Dec 26;68(26):10030-9.

PMID:
14682697
14.

Binding of madindoline A to the extracellular domain of gp130.

Saleh AZ, Greenman KL, Billings S, Van Vranken DL, Krolewski JJ.

Biochemistry. 2005 Aug 16;44(32):10822-7.

PMID:
16086584
15.

Synthesis and structural characterization of pincer type bicyclic diacyloxy- and diazaselenuranes.

Selvakumar K, Singh HB, Goel N, Singh UP, Butcher RJ.

Dalton Trans. 2011 Oct 14;40(38):9858-67. doi: 10.1039/c1dt10862j.

PMID:
21850325
17.

EDOTn and MIM, new peptide backbone protecting groups.

Isidro-Llobet A, Just-Baringo X, Alvarez M, Albericio F.

Biopolymers. 2008;90(3):444-9.

PMID:
17685396
18.

Chemoenzymatic formal synthesis of (-)- and (+)-epibatidine.

Boyd DR, Sharma ND, Kaik M, McIntyre PB, Stevenson PJ, Allen CC.

Org Biomol Chem. 2012 Apr 14;10(14):2774-9. doi: 10.1039/c2ob06904k.

PMID:
22367429
19.

A symmetry-based formal synthesis of zaragozic acid A.

Freeman-Cook KD, Halcomb RL.

J Org Chem. 2000 Sep 22;65(19):6153-9.

PMID:
10987953
20.

Stereoselective synthesis of a dioxa-bicyclo[3.2.1]octane SGLT2 inhibitor.

Mascitti V, Préville C.

Org Lett. 2010 Jul 2;12(13):2940-3. doi: 10.1021/ol100940w.

PMID:
20527898

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