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Items: 1 to 20 of 200

1.

Transcription factor C/EBPα-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia.

Katzerke C, Madan V, Gerloff D, Bräuer-Hartmann D, Hartmann JU, Wurm AA, Müller-Tidow C, Schnittger S, Tenen DG, Niederwieser D, Behre G.

Blood. 2013 Oct 3;122(14):2433-42. doi: 10.1182/blood-2012-12-472183. Epub 2013 Aug 23.

2.

C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations.

Pulikkan JA, Peramangalam PS, Dengler V, Ho PA, Preudhomme C, Meshinchi S, Christopeit M, Nibourel O, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G.

Blood. 2010 Dec 16;116(25):5638-49. doi: 10.1182/blood-2010-04-281600. Epub 2010 Oct 1.

3.

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia.

Pulikkan JA, Dengler V, Peramangalam PS, Peer Zada AA, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G.

Blood. 2010 Mar 4;115(9):1768-78. doi: 10.1182/blood-2009-08-240101. Epub 2009 Dec 22.

4.

Disruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.

Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Müller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G.

Nat Commun. 2017 Jun 29;8(1):46. doi: 10.1038/s41467-017-00032-6.

5.

Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML.

Pulikkan JA, Dengler V, Peer Zada AA, Kawasaki A, Geletu M, Pasalic Z, Bohlander SK, Ryo A, Tenen DG, Behre G.

Leukemia. 2010 May;24(5):914-23. doi: 10.1038/leu.2010.37. Epub 2010 Apr 8.

6.

E6AP, an E3 ubiquitin ligase negatively regulates granulopoiesis by targeting transcription factor C/EBPα for ubiquitin-mediated proteasome degradation.

Pal P, Lochab S, Kanaujiya JK, Kapoor I, Sanyal S, Behre G, Trivedi AK.

Cell Death Dis. 2013 Apr 18;4:e590. doi: 10.1038/cddis.2013.120.

7.

Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.

Hickey CJ, Schwind S, Radomska HS, Dorrance AM, Santhanam R, Mishra A, Wu YZ, Alachkar H, Maharry K, Nicolet D, Mrózek K, Walker A, Eiring AM, Whitman SP, Becker H, Perrotti D, Wu LC, Zhao X, Fehniger TA, Vij R, Byrd JC, Blum W, Lee LJ, Caligiuri MA, Bloomfield CD, Garzon R, Marcucci G.

Blood. 2013 Jan 3;121(1):159-69. doi: 10.1182/blood-2012-05-428573. Epub 2012 Oct 25.

8.

C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia.

Hughes JM, Legnini I, Salvatori B, Masciarelli S, Marchioni M, Fazi F, Morlando M, Bozzoni I, Fatica A.

Oncotarget. 2015 Jul 30;6(21):18534-44.

9.

Acetylation of C/EBPα inhibits its granulopoietic function.

Bararia D, Kwok HS, Welner RS, Numata A, Sárosi MB, Yang H, Wee S, Tschuri S, Ray D, Weigert O, Levantini E, Ebralidze AK, Gunaratne J, Tenen DG.

Nat Commun. 2016 Mar 23;7:10968. doi: 10.1038/ncomms10968.

10.

A C-terminal mutant of CCAAT-enhancer-binding protein α (C/EBPα-Cm) downregulates Csf1r, a potent accelerator in the progression of acute myeloid leukemia with C/EBPα-Cm.

Togami K, Kitaura J, Uchida T, Inoue D, Nishimura K, Kawabata KC, Nagase R, Horikawa S, Izawa K, Fukuyama T, Nakahara F, Oki T, Harada Y, Harada H, Aburatani H, Kitamura T.

Exp Hematol. 2015 Apr;43(4):300-8.e1. doi: 10.1016/j.exphem.2014.11.011. Epub 2014 Dec 20.

PMID:
25534203
11.

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

Pabst T, Mueller BU, Harakawa N, Schoch C, Haferlach T, Behre G, Hiddemann W, Zhang DE, Tenen DG.

Nat Med. 2001 Apr;7(4):444-51.

PMID:
11283671
12.

C/EBPalpha and the pathophysiology of acute myeloid leukemia.

Mueller BU, Pabst T.

Curr Opin Hematol. 2006 Jan;13(1):7-14. Review.

PMID:
16319681
13.

Regulation of the C/EBPα signaling pathway in acute myeloid leukemia (Review).

Song G, Wang L, Bi K, Jiang G.

Oncol Rep. 2015 May;33(5):2099-106. doi: 10.3892/or.2015.3848. Epub 2015 Mar 10. Review.

PMID:
25760953
14.

C/EBPα in normal and malignant myelopoiesis.

Friedman AD.

Int J Hematol. 2015 Apr;101(4):330-41. doi: 10.1007/s12185-015-1764-6. Epub 2015 Mar 10. Review.

15.

MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets.

Su R, Lin HS, Zhang XH, Yin XL, Ning HM, Liu B, Zhai PF, Gong JN, Shen C, Song L, Chen J, Wang F, Zhao HL, Ma YN, Yu J, Zhang JW.

Oncogene. 2015 Jun;34(25):3226-39. doi: 10.1038/onc.2014.274. Epub 2014 Sep 1.

PMID:
25174404
16.

Identification of the C/EBPα C-terminal tail residues involved in the protein interaction with GABP and their potency in myeloid differentiation of K562 cells.

Shimokawa T, Nunomura S, Fujisawa D, Ra C.

Biochim Biophys Acta. 2013 Nov;1829(11):1207-17. doi: 10.1016/j.bbagrm.2013.09.004. Epub 2013 Sep 27.

PMID:
24076158
17.

MicroRNA-661, a c/EBPalpha target, inhibits metastatic tumor antigen 1 and regulates its functions.

Reddy SD, Pakala SB, Ohshiro K, Rayala SK, Kumar R.

Cancer Res. 2009 Jul 15;69(14):5639-42. doi: 10.1158/0008-5472.CAN-09-0898. Epub 2009 Jul 7.

18.

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia.

Pabst T, Mueller BU, Zhang P, Radomska HS, Narravula S, Schnittger S, Behre G, Hiddemann W, Tenen DG.

Nat Genet. 2001 Mar;27(3):263-70.

PMID:
11242107
19.

The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression.

Kuo YY, Hou HA, Chen YK, Li LY, Chen PH, Tseng MH, Huang CF, Lee FY, Liu MC, Liu CW, Chou WC, Liu CY, Tang JL, Yao M, Tien HF.

Haematologica. 2014 Dec;99(12):1799-807. doi: 10.3324/haematol.2014.107821. Epub 2014 Sep 5.

20.

Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment.

Rangatia J, Vangala RK, Treiber N, Zhang P, Radomska H, Tenen DG, Hiddemann W, Behre G.

Mol Cell Biol. 2002 Dec;22(24):8681-94.

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