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Items: 1 to 20 of 89


Extracellular lipid metabolism influences the survival of ovarian cancer cells.

Kuwata S, Ohkubo K, Kumamoto S, Yamaguchi N, Izuka N, Murota K, Tsujiuchi T, Iwamori M, Fukushima N.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):280-4. doi: 10.1016/j.bbrc.2013.08.041. Epub 2013 Aug 21.


The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer.

Tanyi JL, Morris AJ, Wolf JK, Fang X, Hasegawa Y, Lapushin R, Auersperg N, Sigal YJ, Newman RA, Felix EA, Atkinson EN, Mills GB.

Cancer Res. 2003 Mar 1;63(5):1073-82.


Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells.

Mukherjee A, Wu J, Barbour S, Fang X.

J Biol Chem. 2012 Jul 20;287(30):24990-5000. doi: 10.1074/jbc.M112.340083. Epub 2012 Jun 3.


Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer.

Tanyi JL, Hasegawa Y, Lapushin R, Morris AJ, Wolf JK, Berchuck A, Lu K, Smith DI, Kalli K, Hartmann LC, McCune K, Fishman D, Broaddus R, Cheng KW, Atkinson EN, Yamal JM, Bast RC, Felix EA, Newman RA, Mills GB.

Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3534-45.


Activation of AMP-activated protein kinase is essential for lysophosphatidic acid-induced cell migration in ovarian cancer cells.

Kim EK, Park JM, Lim S, Choi JW, Kim HS, Seok H, Seo JK, Oh K, Lee DS, Kim KT, Ryu SH, Suh PG.

J Biol Chem. 2011 Jul 8;286(27):24036-45. doi: 10.1074/jbc.M110.209908. Epub 2011 May 20.


[Lysophosphatidic acid as a potential target for treatment and molecular diagnosis of epithelial ovarian cancers].

Tanyi J, Rigó J Jr.

Orv Hetil. 2009 Jun 14;150(24):1109-18. Review. Hungarian.


Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients.

Xu Y, Gaudette DC, Boynton JD, Frankel A, Fang XJ, Sharma A, Hurteau J, Casey G, Goodbody A, Mellors A, et al.

Clin Cancer Res. 1995 Oct;1(10):1223-32.


Roles of LPA in ovarian cancer development and progression.

Pua TL, Wang FQ, Fishman DA.

Future Oncol. 2009 Dec;5(10):1659-73. doi: 10.2217/fon.09.120. Review.


Lysophosphatidic acid is a major regulator of growth-regulated oncogene alpha in ovarian cancer.

Lee Z, Swaby RF, Liang Y, Yu S, Liu S, Lu KH, Bast RC Jr, Mills GB, Fang X.

Cancer Res. 2006 Mar 1;66(5):2740-8.


Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells.

Mukherjee A, Ma Y, Yuan F, Gong Y, Fang Z, Mohamed EM, Berrios E, Shao H, Fang X.

Neoplasia. 2015 Sep;17(9):723-34. doi: 10.1016/j.neo.2015.09.003.


Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells.

Hu YL, Albanese C, Pestell RG, Jaffe RB.

J Natl Cancer Inst. 2003 May 21;95(10):733-40.


Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells.

Ren J, Xiao YJ, Singh LS, Zhao X, Zhao Z, Feng L, Rose TM, Prestwich GD, Xu Y.

Cancer Res. 2006 Mar 15;66(6):3006-14.


[Expression of lysophosphatidic acid receptor in human ovarian cancer cell lines 3AO, SKOV3, OVCAR3 and its significance].

Wang P, Wu XH, Chen WX, Shan BE, Guo Q.

Di Yi Jun Yi Da Xue Xue Bao. 2005 Nov;25(11):1422-4, 1431. Chinese.


Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis.

Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB.

PLoS One. 2009;4(5):e5583. doi: 10.1371/journal.pone.0005583. Epub 2009 May 15.


Hypoxia enhances lysophosphatidic acid responsiveness in ovarian cancer cells and lysophosphatidic acid induces ovarian tumor metastasis in vivo.

Kim KS, Sengupta S, Berk M, Kwak YG, Escobar PF, Belinson J, Mok SC, Xu Y.

Cancer Res. 2006 Aug 15;66(16):7983-90.


Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.

Saunders JA, Rogers LC, Klomsiri C, Poole LB, Daniel LW.

Free Radic Biol Med. 2010 Dec 15;49(12):2058-67. doi: 10.1016/j.freeradbiomed.2010.10.663. Epub 2010 Oct 8.


Lysophosphatidic acid downregulates tissue inhibitor of metalloproteinases, which are negatively involved in lysophosphatidic acid-induced cell invasion.

Sengupta S, Kim KS, Berk MP, Oates R, Escobar P, Belinson J, Li W, Lindner DJ, Williams B, Xu Y.

Oncogene. 2007 May 3;26(20):2894-901. Epub 2006 Nov 27.


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