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Items: 1 to 20 of 86

1.

A Central role for mTOR in lipid homeostasis.

Lamming DW, Sabatini DM.

Cell Metab. 2013 Oct 1;18(4):465-9. doi: 10.1016/j.cmet.2013.08.002. Epub 2013 Aug 22. Review.

2.

Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects.

Cai H, Dong LQ, Liu F.

Trends Pharmacol Sci. 2016 Apr;37(4):303-17. doi: 10.1016/j.tips.2015.11.011. Epub 2015 Dec 14. Review.

3.

The Roles of mTOR Complexes in Lipid Metabolism.

Caron A, Richard D, Laplante M.

Annu Rev Nutr. 2015;35:321-48. doi: 10.1146/annurev-nutr-071714-034355. Review.

PMID:
26185979
4.

The role of mTOR in lipid homeostasis and diabetes progression.

Chakrabarti P, Kandror KV.

Curr Opin Endocrinol Diabetes Obes. 2015 Oct;22(5):340-6. doi: 10.1097/MED.0000000000000187. Review.

PMID:
26241026
5.

Hypothalamic mTOR: the rookie energy sensor.

Martínez de Morentin PB, Martinez-Sanchez N, Roa J, Ferno J, Nogueiras R, Tena-Sempere M, Dieguez C, Lopez M.

Curr Mol Med. 2014 Jan;14(1):3-21. Review.

PMID:
24236459
6.

DEPTOR-mTOR Signaling Is Critical for Lipid Metabolism and Inflammation Homeostasis of Lymphocytes in Human PBMC Culture.

Xie QB, Liang Y, Yang M, Yang Y, Cen XM, Yin G.

J Immunol Res. 2017;2017:5252840. doi: 10.1155/2017/5252840. Epub 2017 Feb 27.

7.

Influence of mTOR in energy and metabolic homeostasis.

Haissaguerre M, Saucisse N, Cota D.

Mol Cell Endocrinol. 2014 Nov;397(1-2):67-77. doi: 10.1016/j.mce.2014.07.015. Epub 2014 Aug 7. Review.

PMID:
25109278
8.

Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.

Kumar A, Lawrence JC Jr, Jung DY, Ko HJ, Keller SR, Kim JK, Magnuson MA, Harris TE.

Diabetes. 2010 Jun;59(6):1397-406. doi: 10.2337/db09-1061. Epub 2010 Mar 23.

9.

The multifaceted role of mTORC1 in the control of lipid metabolism.

Ricoult SJ, Manning BD.

EMBO Rep. 2013 Mar 1;14(3):242-51. doi: 10.1038/embor.2013.5. Epub 2012 Feb 12. Review.

10.

mTOR signaling in cellular and organismal energetics.

Albert V, Hall MN.

Curr Opin Cell Biol. 2015 Apr;33:55-66. doi: 10.1016/j.ceb.2014.12.001. Epub 2014 Dec 31. Review.

PMID:
25554914
11.

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.

Hagiwara A, Cornu M, Cybulski N, Polak P, Betz C, Trapani F, Terracciano L, Heim MH, Rüegg MA, Hall MN.

Cell Metab. 2012 May 2;15(5):725-38. doi: 10.1016/j.cmet.2012.03.015. Epub 2012 Apr 19.

12.

Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2).

Lamming DW, Demirkan G, Boylan JM, Mihaylova MM, Peng T, Ferreira J, Neretti N, Salomon A, Sabatini DM, Gruppuso PA.

FASEB J. 2014 Jan;28(1):300-15. doi: 10.1096/fj.13-237743. Epub 2013 Sep 26.

13.

Effects of inhibiting PI3K-Akt-mTOR pathway on lipid metabolism homeostasis in goose primary hepatocytes.

Liu DD, Han CC, Wan HF, He F, Xu HY, Wei SH, Du XH, Xu F.

Animal. 2016 Aug;10(8):1319-27. doi: 10.1017/S1751731116000380. Epub 2016 Mar 9.

PMID:
26956906
14.

Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.

Li Z, Xu G, Qin Y, Zhang C, Tang H, Yin Y, Xiang X, Li Y, Zhao J, Mulholland M, Zhang W.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13163-8. doi: 10.1073/pnas.1411571111. Epub 2014 Aug 25.

15.

Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling.

Zhang D, Tong X, Arthurs B, Guha A, Rui L, Kamath A, Inoki K, Yin L.

J Biol Chem. 2014 Sep 12;289(37):25925-35. doi: 10.1074/jbc.M114.567628. Epub 2014 Jul 25.

16.

mTOR signaling in growth control and disease.

Laplante M, Sabatini DM.

Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017. Review.

17.

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion.

Blanchard PG, Festuccia WT, Houde VP, St-Pierre P, Brûlé S, Turcotte V, Côté M, Bellmann K, Marette A, Deshaies Y.

J Lipid Res. 2012 Jun;53(6):1117-25. doi: 10.1194/jlr.M021485. Epub 2012 Mar 30.

18.

The role of mechanistic target of rapamycin (mTOR) complexes signaling in the immune responses.

Soliman GA.

Nutrients. 2013 Jun 19;5(6):2231-57. doi: 10.3390/nu5062231. Review.

19.

Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.

Liu M, Bai J, He S, Villarreal R, Hu D, Zhang C, Yang X, Liang H, Slaga TJ, Yu Y, Zhou Z, Blenis J, Scherer PE, Dong LQ, Liu F.

Cell Metab. 2014 Jun 3;19(6):967-80. doi: 10.1016/j.cmet.2014.03.018. Epub 2014 Apr 17.

20.

Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes.

Mullins GR, Wang L, Raje V, Sherwood SG, Grande RC, Boroda S, Eaton JM, Blancquaert S, Roger PP, Leitinger N, Harris TE.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17450-5. doi: 10.1073/pnas.1410530111. Epub 2014 Nov 24.

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