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Items: 1 to 20 of 109

1.

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, Pan F, Zaiss DM, Coffer PJ.

Immunity. 2013 Aug 22;39(2):259-71. doi: 10.1016/j.immuni.2013.05.018.

2.

N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells.

Mor A, Keren G, Kloog Y, George J.

Eur J Immunol. 2008 Jun;38(6):1493-502. doi: 10.1002/eji.200838292.

3.

The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.

Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B.

Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006.

4.

Ablation of peroxiredoxin II attenuates experimental colitis by increasing FoxO1-induced Foxp3+ regulatory T cells.

Won HY, Jang EJ, Lee K, Oh S, Kim HK, Woo HA, Kang SW, Yu DY, Rhee SG, Hwang ES.

J Immunol. 2013 Oct 15;191(8):4029-37. doi: 10.4049/jimmunol.1203247. Epub 2013 Sep 18.

5.

Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.

Yang R, Qu C, Zhou Y, Konkel JE, Shi S, Liu Y, Chen C, Liu S, Liu D, Chen Y, Zandi E, Chen W, Zhou Y, Shi S.

Immunity. 2015 Aug 18;43(2):251-63. doi: 10.1016/j.immuni.2015.07.017. Epub 2015 Aug 11.

6.

"Default" generation of neonatal regulatory T cells.

Wang G, Miyahara Y, Guo Z, Khattar M, Stepkowski SM, Chen W.

J Immunol. 2010 Jul 1;185(1):71-8. doi: 10.4049/jimmunol.0903806. Epub 2010 May 24.

7.

Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis.

Feng T, Cao AT, Weaver CT, Elson CO, Cong Y.

Gastroenterology. 2011 Jun;140(7):2031-43. doi: 10.1053/j.gastro.2011.03.009. Epub 2011 Mar 17.

8.

DNA methylation controls Foxp3 gene expression.

Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J.

Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105.

9.

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

van Loosdregt J, Vercoulen Y, Guichelaar T, Gent YY, Beekman JM, van Beekum O, Brenkman AB, Hijnen DJ, Mutis T, Kalkhoven E, Prakken BJ, Coffer PJ.

Blood. 2010 Feb 4;115(5):965-74. doi: 10.1182/blood-2009-02-207118. Epub 2009 Dec 7.

10.

Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25- T lymphocytes.

Brillard E, Pallandre JR, Chalmers D, Ryffel B, Radlovic A, Seilles E, Rohrlich PS, Pivot X, Tiberghien P, Saas P, Borg C.

Exp Hematol. 2007 Mar;35(3):416-25.

PMID:
17309822
11.

A degrading view of regulatory T cells.

Laurence A, Belkaid Y, O'Shea JJ.

Immunity. 2013 Aug 22;39(2):201-3. doi: 10.1016/j.immuni.2013.08.017.

12.

Role of STAT3 in CD4+CD25+FOXP3+ regulatory lymphocyte generation: implications in graft-versus-host disease and antitumor immunity.

Pallandre JR, Brillard E, Créhange G, Radlovic A, Remy-Martin JP, Saas P, Rohrlich PS, Pivot X, Ling X, Tiberghien P, Borg C.

J Immunol. 2007 Dec 1;179(11):7593-604.

13.

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota.

Round JL, Mazmanian SK.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12204-9. doi: 10.1073/pnas.0909122107. Epub 2010 Jun 21.

14.

Canonical Wnt signaling negatively modulates regulatory T cell function.

van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ.

Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15.

15.

IκB(NS) protein mediates regulatory T cell development via induction of the Foxp3 transcription factor.

Schuster M, Glauben R, Plaza-Sirvent C, Schreiber L, Annemann M, Floess S, Kühl AA, Clayton LK, Sparwasser T, Schulze-Osthoff K, Pfeffer K, Huehn J, Siegmund B, Schmitz I.

Immunity. 2012 Dec 14;37(6):998-1008. doi: 10.1016/j.immuni.2012.08.023. Epub 2012 Nov 29.

16.

FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.

Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW.

J Clin Invest. 2015 Mar 2;125(3):1111-23. doi: 10.1172/JCI77088. Epub 2015 Feb 2. Erratum in: J Clin Invest. 2015 Aug 3;125(8):3304.

17.

Intravenous immunoglobulin attenuates airway inflammation through induction of forkhead box protein 3-positive regulatory T cells.

Massoud AH, Guay J, Shalaby KH, Bjur E, Ablona A, Chan D, Nouhi Y, McCusker CT, Mourad MW, Piccirillo CA, Mazer BD.

J Allergy Clin Immunol. 2012 Jun;129(6):1656-65.e3. doi: 10.1016/j.jaci.2012.02.050. Epub 2012 May 5.

PMID:
22564681
18.

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity.

Wang L, Kumar S, Dahiya S, Wang F, Wu J, Newick K, Han R, Samanta A, Beier UH, Akimova T, Bhatti TR, Nicholson B, Kodrasov MP, Agarwal S, Sterner DE, Gu W, Weinstock J, Butt TR, Albelda SM, Hancock WW.

EBioMedicine. 2016 Nov;13:99-112. doi: 10.1016/j.ebiom.2016.10.018. Epub 2016 Oct 15.

19.

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

Wang L, Liu Y, Han R, Beier UH, Thomas RM, Wells AD, Hancock WW.

Mol Cell Biol. 2013 Oct;33(20):4106-15. doi: 10.1128/MCB.00144-13. Epub 2013 Aug 26.

20.

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.

Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger EP, Reid SP, Levy DE, Bromberg JS.

J Immunol. 2009 Jan 1;182(1):259-73.

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