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Items: 1 to 20 of 90

1.

Enhanced cytotoxicity from deoxyguanosine-enriched T-oligo in prostate cancer cells.

Rankin AM, Forman L, Sarkar S, Faller DV.

Nucleic Acid Ther. 2013 Oct;23(5):311-21. doi: 10.1089/nat.2013.0420. Epub 2013 Aug 24.

2.

Telomere-homologous G-rich oligonucleotides sensitize human ovarian cancer cells to TRAIL-induced growth inhibition and apoptosis.

Sarkar S, Faller DV.

Nucleic Acid Ther. 2013 Jun;23(3):167-74. doi: 10.1089/nat.2012.0401. Epub 2013 May 2.

3.

Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells.

Rankin AM, Sarkar S, Faller DV.

J Cell Physiol. 2012 Jun;227(6):2586-94. doi: 10.1002/jcp.22997.

4.

T-oligo as an anticancer agent in colorectal cancer.

Wojdyla L, Stone AL, Sethakorn N, Uppada SB, Devito JT, Bissonnette M, Puri N.

Biochem Biophys Res Commun. 2014 Apr 4;446(2):596-601. doi: 10.1016/j.bbrc.2014.03.013. Epub 2014 Mar 12.

5.

Mechanism of Action of G-Quadruplex-Forming Oligonucleotide Homologous to the Telomere Overhang in Melanoma.

Chhabra G, Wojdyla L, Frakes M, Schrank Z, Leviskas B, Ivancich M, Vinay P, Ganapathy R, Ramirez BE, Puri N.

J Invest Dermatol. 2018 Apr;138(4):903-910. doi: 10.1016/j.jid.2017.11.021. Epub 2017 Dec 2.

PMID:
29203363
6.

Telomerase inhibitors and 'T-oligo' as cancer therapeutics: contrasting molecular mechanisms of cytotoxicity.

Rankin AM, Faller DV, Spanjaard RA.

Anticancer Drugs. 2008 Apr;19(4):329-38. doi: 10.1097/CAD.0b013e3282f5d4c2. Review.

PMID:
18454043
8.

T-oligo induces apoptosis in advanced prostate cancer cells.

Gnanasekar M, Thirugnanam S, Zheng G, Chen A, Ramaswamy K.

Oligonucleotides. 2009 Sep;19(3):287-92. doi: 10.1089/oli.2009.0179.

PMID:
19642913
9.

Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways.

Chen Y, Zheng L, Liu J, Zhou Z, Cao X, Lv X, Chen F.

Int Immunopharmacol. 2014 Aug;21(2):447-55. doi: 10.1016/j.intimp.2014.05.026. Epub 2014 Jun 3.

PMID:
24905636
10.

Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer.

Kregel S, Kiriluk KJ, Rosen AM, Cai Y, Reyes EE, Otto KB, Tom W, Paner GP, Szmulewitz RZ, Vander Griend DJ.

PLoS One. 2013;8(1):e53701. doi: 10.1371/journal.pone.0053701. Epub 2013 Jan 11.

11.

The effect of the TRF2 N-terminal and TRFH regions on telomeric G-quadruplex structures.

Pedroso IM, Hayward W, Fletcher TM.

Nucleic Acids Res. 2009 Apr;37(5):1541-54. doi: 10.1093/nar/gkn1081. Epub 2009 Jan 12.

13.

T-oligos inhibit growth and induce apoptosis in human ovarian cancer cells.

Sarkar S, Faller DV.

Oligonucleotides. 2011 Feb;21(1):47-53. doi: 10.1089/oli.2010.0259. Epub 2011 Jan 31.

14.

Telomere-based DNA damage responses: a new approach to melanoma.

Puri N, Eller MS, Byers HR, Dykstra S, Kubera J, Gilchrest BA.

FASEB J. 2004 Sep;18(12):1373-81.

PMID:
15333580
15.

Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides.

Li GZ, Eller MS, Hanna K, Gilchrest BA.

Exp Cell Res. 2004 Dec 10;301(2):189-200.

PMID:
15530855
16.

Telomeric DNA induces p53-dependent reactive oxygen species and protects against oxidative damage.

Lee MS, Yaar M, Eller MS, Rünger TM, Gao Y, Gilchrest BA.

J Dermatol Sci. 2009 Dec;56(3):154-62. doi: 10.1016/j.jdermsci.2009.08.008. Epub 2009 Nov 10.

17.

Highly fluorescent guanosine mimics for folding and energy transfer studies.

Dumas A, Luedtke NW.

Nucleic Acids Res. 2011 Aug;39(15):6825-34. doi: 10.1093/nar/gkr281. Epub 2011 May 6.

18.

L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.

Chung LC, Tsui KH, Feng TH, Lee SL, Chang PL, Juang HH.

Am J Physiol Cell Physiol. 2012 Feb 15;302(4):C676-85. doi: 10.1152/ajpcell.00180.2011. Epub 2011 Nov 23.

19.

Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment.

Weng D, Cunin MC, Song B, Price BD, Eller MS, Gilchrest BA, Calderwood SK, Gong J.

Breast Cancer Res. 2010;12(5):R71. doi: 10.1186/bcr2639. Epub 2010 Sep 16.

20.

Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells.

Kolhatkar V, Khambati H, Lote A, Shanine P, Insley T, Sen S, Munirathinam G, Král P, Kolhatkar R.

Pharm Res. 2015 Jan;32(1):196-210. doi: 10.1007/s11095-014-1455-7. Epub 2014 Aug 5.

PMID:
25092067

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