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Items: 1 to 20 of 102

1.

Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice.

Schemmer J, Araúzo-Bravo MJ, Haas N, Schäfer S, Weber SN, Becker A, Eckert D, Zimmer A, Nettersheim D, Schorle H.

PLoS One. 2013 Aug 13;8(8):e71113. doi: 10.1371/journal.pone.0071113. eCollection 2013. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/579ac618-0ed0-4451-a4fc-10bad989024b.

2.

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line.

Krentz AD, Murphy MW, Zhang T, Sarver AL, Jain S, Griswold MD, Bardwell VJ, Zarkower D.

Dev Biol. 2013 May 1;377(1):67-78. doi: 10.1016/j.ydbio.2013.02.014. Epub 2013 Mar 6.

3.

The role of BLIMP1 and its putative downstream target TFAP2C in germ cell development and germ cell tumours.

Schäfer S, Anschlag J, Nettersheim D, Haas N, Pawig L, Schorle H.

Int J Androl. 2011 Aug;34(4 Pt 2):e152-8; discussion e158-9. doi: 10.1111/j.1365-2605.2011.01167.x. Epub 2011 May 12. Review.

PMID:
21564135
4.

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.

Murakami K, Günesdogan U, Zylicz JJ, Tang WWC, Sengupta R, Kobayashi T, Kim S, Butler R, Dietmann S, Surani MA.

Nature. 2016 Jan 21;529(7586):403-407. doi: 10.1038/nature16480. Epub 2016 Jan 11.

5.

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8. doi: 10.1073/pnas.0905431106. Epub 2009 Dec 10.

6.

Induction of mouse germ-cell fate by transcription factors in vitro.

Nakaki F, Hayashi K, Ohta H, Kurimoto K, Yabuta Y, Saitou M.

Nature. 2013 Sep 12;501(7466):222-6. doi: 10.1038/nature12417. Epub 2013 Aug 4.

PMID:
23913270
7.

Does mouse embryo primordial germ cell activation start before implantation as suggested by single-cell transcriptomics dynamics?

Gerovska D, Araúzo-Bravo MJ.

Mol Hum Reprod. 2016 Mar;22(3):208-25. doi: 10.1093/molehr/gav072. Epub 2016 Jan 5.

PMID:
26740066
8.

Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.

Cook MS, Munger SC, Nadeau JH, Capel B.

Development. 2011 Jan;138(1):23-32. doi: 10.1242/dev.057000. Epub 2010 Nov 29.

9.
10.

Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer.

Kulak MV, Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T, Price DH, Domann FE, Weigel RJ.

Oncogene. 2013 Aug 22;32(34):4043-51. doi: 10.1038/onc.2012.400. Epub 2012 Sep 10.

11.

Critical function of AP-2 gamma/TCFAP2C in mouse embryonic germ cell maintenance.

Weber S, Eckert D, Nettersheim D, Gillis AJ, Schäfer S, Kuckenberg P, Ehlermann J, Werling U, Biermann K, Looijenga LH, Schorle H.

Biol Reprod. 2010 Jan;82(1):214-23. doi: 10.1095/biolreprod.109.078717. Epub 2009 Sep 23.

PMID:
19776388
12.

Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest.

Sharma N, Kubaczka C, Kaiser S, Nettersheim D, Mughal SS, Riesenberg S, Hölzel M, Winterhager E, Schorle H.

Development. 2016 Mar 1;143(5):787-98. doi: 10.1242/dev.128553. Epub 2016 Jan 25.

13.

Transcription factor AP-2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage.

Cao Z, Carey TS, Ganguly A, Wilson CA, Paul S, Knott JG.

Development. 2015 May 1;142(9):1606-15. doi: 10.1242/dev.120238. Epub 2015 Apr 9.

14.

Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice.

Heaney JD, Anderson EL, Michelson MV, Zechel JL, Conrad PA, Page DC, Nadeau JH.

Development. 2012 May;139(9):1577-86. doi: 10.1242/dev.076851. Epub 2012 Mar 21.

15.

DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells.

Chen HH, Welling M, Bloch DB, Muñoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N.

Stem Cell Reports. 2014 Nov 11;3(5):892-904. doi: 10.1016/j.stemcr.2014.09.003. Epub 2014 Oct 11.

16.

Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.

Woodfield GW, Hitchler MJ, Chen Y, Domann FE, Weigel RJ.

Clin Cancer Res. 2009 Jun 1;15(11):3672-9. doi: 10.1158/1078-0432.CCR-08-2343. Epub 2009 May 19.

17.

Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells.

Panula S, Reda A, Stukenborg JB, Ramathal C, Sukhwani M, Albalushi H, Edsgärd D, Nakamura M, Söder O, Orwig KE, Yamanaka S, Reijo Pera RA, Hovatta O.

PLoS One. 2016 Oct 21;11(10):e0165268. doi: 10.1371/journal.pone.0165268. eCollection 2016.

18.

A tripartite transcription factor network regulates primordial germ cell specification in mice.

Magnúsdóttir E, Dietmann S, Murakami K, Günesdogan U, Tang F, Bao S, Diamanti E, Lao K, Gottgens B, Azim Surani M.

Nat Cell Biol. 2013 Aug;15(8):905-15. doi: 10.1038/ncb2798. Epub 2013 Jul 14.

19.

LIN28 is selectively expressed by primordial and pre-meiotic germ cells in the human fetal ovary.

Childs AJ, Kinnell HL, He J, Anderson RA.

Stem Cells Dev. 2012 Sep 1;21(13):2343-9. doi: 10.1089/scd.2011.0730. Epub 2012 Mar 6.

20.

NANOS3 function in human germ cell development.

Julaton VT, Reijo Pera RA.

Hum Mol Genet. 2011 Jun 1;20(11):2238-50. doi: 10.1093/hmg/ddr114. Epub 2011 Mar 19.

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